Results 11 to 20 of about 8,788 (204)
Treatment of Xanthoma disseminatum - a systematic literature review. [PDF]
J Dtsch Dermatol GesSummary Xanthoma disseminatum is a rare disease from the spectrum of non‐Langerhans cell histiocytoses, which can be categorized into three types and is sometimes associated with systemic involvement. Due to the its rarity, there are no standardized treatment guidelines for this disease, making treatment in everyday clinical practice more difficult ...
Hansen-Abeck I +4 more
europepmc +2 more sources
Dispersion-Enhanced Nitrogen-Centered Photocatalysis of the Direct Hydrogen Atom Transfer. [PDF]
Angew Chem Int Ed EnglNitrogen‐centered acridine photocatalysts for direct hydrogen atom transfer have been developed, leveraging dispersion interactions to enhance photocatalytic activity. This approach enables diverse functionalization reactions of strong C─H bonds even under cryogenic conditions and provides a new strategy for boosting the efficiency of direct HAT ...
Zhang J +16 more
europepmc +3 more sources
Treatment of lactating sows with clofibrate as a synthetic agonist of PPARalpha does not influence milk fat content and gains of litters [PDF]
, 1944 BACKGROUND: In rats, it has been observed that treatment with activators of peroxisome proliferator-activated receptor a (PPARalpha) disturbs metabolic adaptations during lactation, which in turn lead to a reduction of milk fat content and gains of ...
Gessner, Denise K. +8 more
core +2 more sources
Benefit of Clofibrate on indirect hyperbilirubinemia in newborn
Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2018 Background: hyperbilirubinemia develop in all newborns and resolves within the first several weeks after birth. Clofibrate is planned for management of indirect hyperbilirubinemia Aim: to evaluate Benefit of Clofibrate on indirect hyperbilirubinemia in ...
Baha D. Moohy Alosy
doaj +1 more source
Regulation of genes involved in carnitine homeostasis by PPARa across different species (rat, mouse, pig, cattle, chicken, and human) [PDF]
, 2012 Recent studies in rodents convincingly demonstrated that PPAR-alpha is a key regulator of genes involved in carnitine homeostasis, which serves as a reasonable explanation for the phenomenon that energy deprivation and fibrate treatment, both of which ...
Egeri, Leonie +4 more
core +1 more source
Cellular Physiology and Biochemistry, 2013 Background and Aims: Clofibrate, an established PPARα ligand, has recently been shown to have anticancer activity yet its mechanisms of action remain to be characterized.
Shuai Wang +3 more
doaj +1 more source
New Aspects of Thromboangiitis obliterans (von Winiwarter-Buerger's Disease) [PDF]
, 1984 The existence of thromboangiitis obliterans as a clinical entity has been a matter of debate for many years. In contrast to other immunovasculitides there is no organ involvement while peripheral vessels are affected.
Berlit, Peter +3 more
core +1 more source
Apoptosis induced by clofibrate in Yoshida AH-130 hepatoma cells
Journal of Lipid Research, 2003 Clofibrate is a hypolipidemic drug belonging to the peroxisome proliferator (42) family. PPs are well-recognized hepatocarcinogens, though only for rodents and not for humans.
Rosa A. Canuto +8 more
doaj +1 more source
Silent Dangers in Elderly Pharmacotherapy: The Interplay of Polypharmacy, Multimorbidity, and Drug Interactions. [PDF]
J Eval Clin PractABSTRACT Background Pharmacological therapy in older persons is inherently complex due to the interplay of age‐related physiological changes, multimorbidity, and polypharmacy. These factors increase the vulnerability of elderly patients to drug interactions and adverse drug reactions.
Ngcobo NN.
europepmc +2 more sources
Molecules, 2019 Myocardial infarction (MI) initiates an inflammatory response that promotes both beneficial and deleterious effects. The early response helps the myocardium to remove damaged tissue; however, a prolonged later response brings cardiac remodeling ...
Luz Ibarra-Lara +9 more
doaj +1 more source