Results 111 to 120 of about 248,407 (299)

Mass production and quality control of teak clones for tropical plantations : the Yayasan Sabah Group and CIRAD joint project as a case study [PDF]

open access: yes, 2007
L'attrait pour des clones de teck qui peuvent être plantés sous forme monospécifique ou en association avec d'autres espèces végétales (agroforesterie) devient de plus en plus évident dans de nombreux pays.
Baillères, Henri   +3 more
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Molecular cancer prevention: Intercepting disease

open access: yesMolecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco   +2 more
wiley   +1 more source

Toward the Development of Garlic Varieties: The First Attempts

open access: yesAgronomy
Despite garlic (Allium sativum L.) being recognized as the second most important species in the Allium genus, a limited number of varieties are available worldwide.
Ricardo Julián Licea-Moreno   +2 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Molecular Analysis by Microsatellite Markers of Goji Plants (Lycium barbarum L.) Grown in Central Italy Reveal Genetic Distinction from Both L. barbarum and L. chinense Species

open access: yesPlants
Lycium barbarum L. is a shrub native to China. It produces berries that are high in nutraceutical value. Its commercial appeal has led to the development of new plantations in Italy over recent decades.
Letizia Poggioni   +7 more
doaj   +1 more source

Optimal routes scheduling for municipal waste disposal garbage trucks using evolutionary algorithm and artificial immune system [PDF]

open access: yesTransport Problems, 2011
This paper describes an application of an evolutionary algorithm and an artificial immune systems to solve a problem of scheduling an optimal route for waste disposal garbage trucks in its daily operation.
Bogna MRÓWCZYŃSKA
doaj  

Possible mass production options for Acacia mangium plantations in Sabah (Malaysia) [PDF]

open access: yes, 1992
Acacia mangium est considéré comme une espèce majeure de reboisement au Sahab pour ses capacités à réhabiliter les sites dégradés et sa croissance remarquable.
Monteuuis, Olivier, Nasi, Robert
core  

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