Results 81 to 90 of about 248,407 (299)

A Novel Hybrid CNN-AIS Visual Pattern Recognition Engine

, 2015
Machine learning methods are used today for most recognition problems. Convolutional Neural Networks (CNN) have time and again proved successful for many image processing tasks primarily for their architecture.
A Borji, A Krizhevsky, E Hart, F Lauer, G Dudek, LN Castro De, N Pinto, S Knerr, T Serre, Y LeCun, Y Shao   +10 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Evolution of RAS Mutational Status in Liquid Biopsies During First-Line Chemotherapy for Metastatic Colorectal Cancer

Frontiers in Oncology, 2020
Treatment options for patients with metastatic colorectal cancer (mCRC) are limited. This particularly affects the largest group of patients with RAS mutations, who are considered ineligible for therapy with antiEGFR antibodies.
Susanne Klein-Scory, Ingo Wahner, Marina Maslova, Yosef Al-Sewaidi, Michael Pohl, Thomas Mika, Swetlana Ladigan, Roland Schroers, Alexander Baraniskin, Alexander Baraniskin   +9 more
doaj   +1 more source

Advances in mass clonal propagation of Eucalyptus urophylla x E. grandis in Congo [PDF]

, 2008
La technique mise au point en 1978 à Pointe-Noire, au Congo, pour bouturer les clones d'eucalyptus hybrides naturels Eucalyptus PF1 et E. 12 ABL x E. saligna s'est avérée inadaptée au bouturage des hybrides artificiels E. urophyla x E. grandis. En effet,
Mankessi, François, Marien, Jean-Noël, Monteuuis, Olivier, Saya, Aubin Rachel, Toto, Mélanie   +4 more
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Application of Artificial Intelligence in Prediction of Road Freight Transportation

Promet (Zagreb), 2017
Road freight transport often requires the prediction of volume. Such knowledge is necessary to capture trends in the industry and support decision making by large and small trucking companies.
Bogna Mrowczynska, Maria Ciesla, Aleksander Krol, Aleksander Sladkowski   +3 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Clonal Expansion in Cardiovascular Pathology

JACC: Basic to Translational Science
Summary: Clonal expansion refers to the proliferation and selection of advantageous “clones” that are better suited for survival in a Darwinian manner.
Alexander Lin, BEng (Hons), Mairi Brittan, PhD, Andrew H. Baker, PhD, Stefanie Dimmeler, PhD, Edward A. Fisher, MD, PhD, Judith C. Sluimer, PhD, Ashish Misra, PhD   +6 more
doaj   +1 more source

EQML- An Evolutionary Qualitative Model Learning Framework [PDF]

, 2006
Postprin
Coghill, George MacLeod, Pang, Wei
core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source