Results 61 to 70 of about 746,964 (209)

Transient down-regulation of beta1 integrin subtypes on kidney carcinoma cells is induced by mechanical contact with endothelial cell membranes [PDF]

, 2007
Adhesion molecules of the integrin beta1 family are thought to be involved in the malignant progression renal cell carcinoma (RCC). Still, it is not clear how they contribute to this process.
Achiwa H, Anastassiou G, Blattner SM, Brenner W, Dufour S, Hegerfeldt Y, Hii CS, Markovic-Lipkovski J, Perlino E, Seftor RE, Yamada S   +10 more
core   +1 more source

Generation of hypoimmunogenic universal iPS cells through HLA-type gene knockout

Experimental and Molecular Medicine
Hypoimmunogenic universal induced pluripotent stemn (iPS) cells were generated through the targeted disruption of key genes, including human leukocyte antigen (HLA)-A, HLA-B and HLA-DR alpha (DRA), using the CRISPR–Cas9 system.
Juryun Kim, Yoojun Nam, Doyeong Jeon, Yujin Choi, SeonJu Choi, Chang Pyo Hong, Siyoung Kim, Hyerin Jung, Narae Park, Yeowon Sohn, Yeri Alice Rim, Ji Hyeon Ju   +11 more
doaj   +1 more source

Characterization of HTLV-1 Infectious Molecular Clone Isolated from Patient with HAM/TSP and Immortalization of Human Primary T-Cell Lines

Viruses
Human T-cell leukemia virus (HTLV-1) is the etiological agent of lymphoproliferative diseases such as adult T-cell leukemia and T-cell lymphoma (ATL) and a neurodegenerative disease known as HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM ...
Marcia Bellon, Pooja Jain, Christophe Nicot   +2 more
doaj   +1 more source

Alterations in integrin expression modulates invasion of pancreatic cancer cells

Journal of Experimental & Clinical Cancer Research, 2009
Background Factors mediating the invasion of pancreatic cancer cells through the extracellular matrix (ECM) are not fully understood. Methods In this study, sub-populations of the human pancreatic cancer cell line, MiaPaCa-2 were established which ...
Crown John, Clynes Martin, Walsh Naomi, O'Donovan Norma   +3 more
doaj   +1 more source

miR-513b-5p inhibits the proliferation and promotes apoptosis of retinoblastoma cells by targeting TRIB1

Open Medicine, 2021
MicroRNAs are involved in the pathogenesis of various human malignant tumors. This study aims to explore the role of miR-513b-5p in the malignant proliferation of retinoblastoma (RB) cells and its potential molecular mechanisms.
Zhang Li-Juan, Wang Fang, Qi Pei-Yan, Zhou Wei-Yan, Wang Bing   +4 more
doaj   +1 more source

From monoclonal antibody to gene for a neuron-specific glycoprotein in Drosophila [PDF]

, 1985
A monoclonal antibody (MAb24B10), derived from mice immunized with Drosophila retina, exclusively stains photoreceptor cells in the retina and their axonal projections to the optic ganglia. The antigen (Ag24B10) is a 160-kDa glycoprotein comprising about
Benzer, Seymour, Venkatesh, T. R., Zipursky, S. L.   +2 more
core  

A molecular basis for selective antagonist destabilization of dopamine D3 receptor quaternary organization [PDF]

, 2017
The dopamine D3 receptor (D3R) is a molecular target for both first-generation and several recently-developed antipsychotic agents. Following stable expression of this mEGFP-tagged receptor, Spatial Intensity Distribution Analysis indicated that a ...
Caltabiano, Gianluigi, Jiménez-Rosés, Mireia, Marsango, Sara, Millan, Mark J., Milligan, Graeme, Pediani, John D., Ward, Richard J.   +6 more
core   +2 more sources

Aldehyde dehydrogenase 1A1 and gelsolin identified as novel invasion-modulating factors in conditioned medium of pancreatic cancer cells [PDF]

, 2008
Conditioned medium (CM) from clonal sub-populations of the pancreatic cancer cell line, MiaPaCa-2 with differing invasive abilities, were examined for their effect on in vitro invasion.
Alban, Albini, Altmeyer, Bendtsen, Bhave, Chaponnier, Collard, Cunningham, Dosaka-Akita, Faivre, Ferlay, Goggins, Han, Holdenrieder, Jelski, Jelski, Jemal, Koya, Kulasingam, Kumar, Kuramitsu, Kwiatkowski, Kwiatkowski, Lee, Lundin, Martin, Martin Clynes, Michael Henry, Moreb, Naomi Walsh, Negm, Ni, Norma O'Donovan, Noske, Okano, Orchekowski, Paul Dowling, Paula Meleady, Safi, Sagawa, Shieh, Sladek, Tanaka, Tanaka, Tanudji, Tempero, Thompson, Thor, Wang, Winston, Yin, Yoshida   +51 more
core   +3 more sources

Cloning of Canine Osteosarcoma Cells.

Journal of Veterinary Medical Science, 1995
Six clonal cells were established from a canine osteosarcoma cell line (POS) by a limiting dilution method using feeder cells. Whereas histology of mass developed in nude mice by transplantation of POS cells revealed various cell types, clonal cells were morphologically consistent in size and shape.
K, Nozaki, K, Okuyama, T, Kadosawa, H, Nakayama, N, Goto, N, Sasaki, A, Takeuchi   +6 more
openaire   +3 more sources

Positional and functional mapping of a neuroblastoma differentiation gene on chromosome 11 [PDF]

, 2005
Background: Loss of chromosome 11q defines a subset of high-stage aggressive neuroblastomas. Deletions are typically large and mapping efforts have thus far not lead to a well defined consensus region, which hampers the identification of positional ...
De Preter, K, Vandesompele, J, Menten, B, Carr, P, Fiegler, H, Edsjö, Anders,, Carter, NP, Yigit, N, Waelput, W, Van Roy, N, Bader, S, Påhlman, Sven,, Speleman, F, Lund University.   +13 more
core   +3 more sources