Results 51 to 60 of about 82,588 (312)

Innovative transdermal drug delivery systems: Benefits, challenges, and emerging application

BMEMat, EarlyView.
The graphical abstract illustrates the diverse nanostructures employed in transdermal drug delivery systems, highlighting their unique mechanisms to penetrate the intricate layers of skin. It provides a detailed representation of the skin's complex anatomy, emphasizing the challenges posed by its barrier properties.
Syed Waqas Ali Shah, Xingxing Li, Hao Yuan, Huiling Shen, Shaohao Quan, Guifang Pan, Muhammad Ishfaq, Abid Ullah Shah, Hanhan Xie, Jundong Shao   +9 more
wiley   +1 more source

Gabapentin versus Clonidine Premedication for Haemodynamic Stability and Postoperative Analgesia in Laparoscopic Cholecystectomy: A Randomised Double-blind Control Study [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Laparoscopic cholecystectomy is associated with haemodynamic stress responses and significant postoperative pain due to CO2 insufflation and peritoneal irritation.
Mahima Manchanda, Seema Tikku Sharma, Kanika Sachdeva, Gurpreet Kaur Atwal, Neha Mehra   +4 more
doaj   +1 more source

Clonidine for management of chronic pain: A brief review of the current evidences

Saudi Journal of Anaesthesia, 2014
Clonidine, an alpha-2 adrenergic receptor agonist, has well-established role in acute perioperative pain management. However, recently it has found increasing use in chronic pain conditions as well. In this review, we systematically searched and analyzed
Anil Kumar, S. Maitra, P. Khanna, D. Baidya   +3 more
semanticscholar   +1 more source

Pharmacologic pitfalls in heart failure: A guide to drugs that may cause or exacerbate heart failure. A European Journal of Heart Failure expert consensus document

European Journal of Heart Failure, EarlyView.
Main categories of harmful drugs in heart failure. CCB, calcium channel blocker; DPP4i, dipeptidyl peptidase‐4 inhibitor; HER2‐TT, human epidermal growth factor receptor 2‐targeted therapy; NSAID, non‐steroidal anti‐inflammatory drug; TKI, tyrosine kinase inhibitor; TZD, thiazolidinedione; VEGF Inh, vascular endothelial growth factor inhibitor.
Amr Abdin, Johann Bauersachs, Magdy Abdelhamid, Suleman Aktaa, Hussam Al Ghorani, Antonio Bayes‐Genis, Jan Biegus, Michael Böhm, Javed Butler, Nicolas Girerd, Marco Metra, Wilfried Mullens, Hadi Skouri, Muthiah Vaduganathan, Seif El Hadidi, Giuseppe M.C. Rosano, Gianluigi Savarese   +16 more
wiley   +1 more source

Sciatic lateral popliteal block with clonidine alone or clonidine plus 0.2% ropivacaine: effect on the intra-and postoperative analgesia for lower extremity surgery in children: a randomized prospective controlled study

BMC Anesthesiology, 2012
Background The effect of adding clonidine to local anesthetics for nerve or plexus blocks remains unclear. Most of the studies in adults have demonstrated the positive effects of clonidine on intra- and postoperative analgesia when used as an adjunctive ...
Petroheilou Kalliopi, Livanios Stavros, Zavras Nikolaos, Hager John, Fassoulaki Argyro   +4 more
doaj   +1 more source

Systematic review: Safety and efficacy of atomoxetine in children and adolescents with autism spectrum disorder

JCPP Advances, EarlyView.
This systematic review aimed to assess the current evidence on the efficacy and safety of Atomoxetine in common clinical symptoms of autism spectrum disorder (ASD) for children and adolescents. With limited studies available, there is a need for more high‐power studies for the use of Atomoxetine in children and adolescents with autism spectrum disorder.
Nihit Gupta, Daniel Boyes, Hunter Hanlon‐Taylor, Mayank Gupta   +3 more
wiley   +1 more source

Effect of Oral Clonidine Premedication on Induction Dose of Propofol and Perioperative Haemodynamic Parameters in Patients Undergoing Laparoscopic Cholecystectomy: A Double-blinded Randomised Controlled Study [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Clonidine increases the effects of anaesthesia and possesses antihypertensive qualities. During laparoscopic cholecystectomy, pneumoperitoneum is created by inflating Carbon Dioxide (CO2), which stimulates autonomic pathways, resulting in ...
Dheer Singh, Rakesh Bahadur Singh, Matendra Singh Yadav, Amit Kumar Singh, Purva Kumrawat, Chandra Bhushan Yadav   +5 more
doaj   +1 more source

Intravenous dexmedetomidine versus clonidine for prolongation of bupivacaine spinal anesthesia and analgesia: A randomized double-blind study

Journal of Anaesthesiology Clinical Pharmacology, 2013
Background: Alpha2-adrenergic agonists have synergistic action with local anesthetics and may prolong the duration of sensory, motor blockade and postoperative analgesia obtained with spinal anesthesia.
V. S. Reddy, Nawaz Ahmed Shaik, Balaji Donthu, Venkata Krishna Reddy Sannala, Venkatsiva Jangam   +4 more
semanticscholar   +1 more source

Differences in patterns of attention deficit/hyperactivity disorder medication use in US children

JCPP Advances, EarlyView.
Abstract Background Understanding attention deficit/hyperactivity disorder (ADHD) medication patterns is crucial for optimizing treatment outcomes. There are limited data on racial, ethnic, gender and socioeconomic treatment differences across longitudinal national samples.
Jennie E. Ryan, Alexander Weigard, Sean Esteban McCabe, Timothy E. Wilens, Philip T. Veliz   +4 more
wiley   +1 more source

The effect of clonidine as preanesthetic medication in children

Iranian South Medical Journal, 2003
Separation of children from their parents at the time of transfer to operating room commonly cause severe anxiety which can induce undesired physiologic and psychologic Sequalea. For the purpose of sedation different pharmacologic and non pharmacological
Behzad Maghsoodi, Seyed Ahmad Rakeie, Seyed Ziaoldin Behin Aeen   +2 more
doaj