Results 181 to 190 of about 759,664 (294)

Targeting RAGE with Nanobodies for Molecular Imaging of Cancers and Alzheimer's Disease

Advanced Biology, EarlyView.
RAGE‐specific nanobodies were isolated via phage display and characterized by ELISA, cell ELISA, and SPR. In vivo imaging in renal carcinoma and Alzheimer's disease mouse models demonstrated that NbF8, the highest‐affinity clone, selectively targeted RAGE‐overexpressing tumors and brain tissues, highlighting its potential as a molecular imaging agent ...
Guangfeng Liang, Fujing Wang, Wei Xiong, Guangwei Shi, Junling Yuan, Yang Li, Hongyan Zhang, Yanmei Xing, Shan Jin, Kongjun Yang, Zhongliang Dai, Jichao Sun, Zhijie Li, Jianhong Wang   +13 more
wiley   +1 more source

Evaluating protein complexes between human aquaporin and calmodulin using biomolecular fluorescence complementation. [PDF]

Sci Rep
Glas J, Landén J, Hedfalk K.
europepmc   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

Protocol for fast antibiotic resistance-based gene editing of mammalian cells with CRISPR-Cas9. [PDF]

STAR Protoc
Adarska P, Fox E, Heyza J, Barnaba C, Schmidt J, Bottanelli F.   +5 more
europepmc   +1 more source

Positional Cloning and the Molecular Basis of Immunodeficiency

Annals of Medicine, 1995
C. I. E. Smith, Leif Hammarström
openaire   +2 more sources

Intersection Between Local Anesthetics and Cancer Biology: What Now? Where Are We Going?

Advanced Biology, EarlyView.
Local anesthetics (LAs), widely used in anesthesia, may also play a role in cancer treatment by inhibiting tumor growth, reducing metastasis, and enhancing immune responses. They modulate key pathways like AKT/mTOR and RAS/ERK while affecting angiogenesis and tumor innervation and the immune response.
Eduardo Nunez‐Rodriguez, Hao Zhang, Dhananjay Sah, Juan P. Cata   +3 more
wiley   +1 more source

Genetic Identification of Brazilian Mammalian Hosts of <i>Trypanosoma cruzi</i>: Improving Blood Meal Source Discrimination in Vector-Borne Transmission. [PDF]

Pathogens
Oliveira QM, Pessanha TS, Iñiguez AM.
europepmc   +1 more source

Structurally Colored Physically Unclonable Functions with Ultra‐Rich and Stable Encoding Capacity

Advanced Functional Materials, Volume 35, Issue 12, March 18, 2025.
This study reports a design strategy for generating bright‐field resolvable physically unclonable functions with extremely rich encoding capacity coupled with outstanding thermal and chemical stability. The optical response emerges from thickness‐dependent structural color formation in ZnO features, which are fabricated by physical vapor deposition ...
Abidin Esidir, Miaoning Ren, Sami Pekdemir, Mustafa Kalay, Nilgun Kayaci, Nail Gunaltay, Hakan Usta, Xian Huang, Mustafa Serdar Onses   +8 more
wiley   +1 more source

Cloning, heterologous expression, and expression analysis of SinSyn7 gene from Sinomenium acutum. [PDF]

PLoS One
Chen J, Chen X, Zhang L, Huang S, Chen X, Huang X, Yang H.   +6 more
europepmc   +1 more source

Bioorthogonal Engineering of Cellular Microenvironments Using Isonitrile Ligations

Advanced Functional Materials, EarlyView.
Highly selective chemistries are required for fabrication and post‐cross–linking modification of cell‐encapsulating hydrogels used in tissue engineering applications. Isonitrile ligation reactions represent a promising class of bioorthogonal chemistries for engineering hydrogel‐based cellular microenvironments. Isonitrile‐based hydrogels are stable and
Ping Zhou, Lauren Brown, Christopher M. Madl   +2 more
wiley   +1 more source