Results 181 to 190 of about 822,631 (292)

Rapid assembly of functional modules for generating human artificial chromosome constructs compatible with epigenetic centromere seeding. [PDF]

Chromosome Res
Birchak GJ, Gibson DG, Allu PK, Kashyap P, Glass JI, Black BE.   +5 more
europepmc   +1 more source

Molecular Cloning of Neuropathy Target Esterase [PDF]

Toxicology Letters, 1996
Michael Lush, David Read, Paul Glynn
openaire   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

CloneCoordinate: Open-Source Software for Collaborative DNA Construction. [PDF]

ACS Synth Biol
Jeon E, Shen Z, Christ S, Qi E, Fan I, Lee N, Morgan O, Ohl M, Millson D, Laker M, Pierson A, Villegas Garcia E, Zhang Y, Choi A, Iyengar A, Kim R, Lee J, Niedeck L, Oeien V, Rashid M, Seetharaman N, Singh A, Soble D, Yu J, Yu K, Berdy S, Chang E, Kitazono R, Ortiz S, Taylor D, Thuronyi B.   +30 more
europepmc   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Identification and analysis of a novel A allele with a c.565A > G variant on the ABO*A1.02 allele leading to subtype A: A case report. [PDF]

Medicine (Baltimore)
Lu W, Mo C, Zhong J, Zhang Y, Li L.
europepmc   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Effects of <i>VeA</i> Gene on the Growth, Pigment and Citrinin Synthesis of <i>Monascus ruber</i> M7. [PDF]

Microorganisms
Kuang L, Ma P, He X, Wang L, Xie Q, He Y, Tan H.   +6 more
europepmc   +1 more source

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source

Study on the High-Efficiency Expression of Horseradish Peroxidase in <i>Pichia pastoris</i>. [PDF]

Molecules
Wang Y, Jing Y, Li W, Wang Y, Li F, Qiu Y, Rao B.   +6 more
europepmc   +1 more source