Comparative genomics of endophytic fungi Apiospora malaysiana with related ascomycetes indicates adaptation attuned to lifestyle choices with potential sustainable cellulolytic activity. [PDF]
Kant S+7 more
europepmc +1 more source
Co‐Selection of Low Cadmium Accumulation and High Yield During Tomato Improvement
This study finds that large‐fruited tomatoes accumulate less cadmium (Cd) compared to wild tomatoes and cherry tomatoes. This is because, during the improvement process of tomato, the low‐Cd allele LCT1A and the large fruit allele fw3.2T are closely linked, leading to a co‐selection event.
Xingyu Zhang+11 more
wiley +1 more source
Optimization of handmade cloning enhances pregnancy rates and live calf production in cattle. [PDF]
Su R+8 more
europepmc +1 more source
Therapeutic Repair of Sperm Quality Decline Caused by Polytetrafluoroethylene
Exposure to PTFE (teflon), a commonly used microplastic in non‐stick cookware, significantly reduces sperm quality in both humans and mice. Specifically, PTFE induces the disruption of sperm cytoskeleton and F‐actin assembly through targeting SKAP2 in haploid spermatid.
Shiming Gan+15 more
wiley +1 more source
Development of a versatile synthetic microbe for the concurrent degradation of organic pollutants. [PDF]
Su C, Jiang S, Dai J.
europepmc +1 more source
Targeting eRNAs from TNFα‐associated super‐enhancers with ASOs effectively reduces TNFα expression and inflammatory responses in both mouse models and patient‐derived immune cells. The conserved nature of these regulatory regions between species highlights the potential of eRNA‐targeted approaches as a therapeutic strategy for chronic inflammatory ...
Minjeong Cho+12 more
wiley +1 more source
Automation-aided construction and characterization of Bacillus subtilis PrsA strains for the secretion of amylases. [PDF]
Hamburger F+6 more
europepmc +1 more source
βFaar selectively targets and inhibits the GTPase activity of the RAB18 protein, thereby reducing LD volume. Conversely, βFaar promotes nuclear translocation of the transcription factor IRF4 in inguinal white adipose tissue (iWAT), facilitating the browning of white adipose tissue and attenuating body fat accumulation.
Yue Yang+13 more
wiley +1 more source
Discovering methylated DNA motifs in bacterial nanopore sequencing data with MIJAMP. [PDF]
Tidwell AK+4 more
europepmc +1 more source