Results 241 to 250 of about 437,074 (308)

Advances in gene cloning and functional genomics approaches for wheat (Triticum aestivum L.) improvement. [PDF]

Plant Genome
Gudi S, Razzaq K, Singh J, Mendoza LDR, Khan M, Gupta R, Gill U.   +6 more
europepmc   +1 more source

Hierarchical Flux‐Protection Engineering Stabilizes Oxidation‐Prone Metabolic Nodes for High‐Level Curcumin Biosynthesis

Advanced Science, EarlyView.
Flux‐protection engineering stabilizes an oxidation‐prone L‐DOPA node in engineered E. coli by combining acid‐adapted chassis evolution, respiratory‐chain modulation, enzyme‐level flux matching, and pH–DO control. Carbon is redirected from oxidative browning to productive biosynthesis, enabling 1075.2 mg/L curcumin and demonstrating transferability to ...
Jianbin Chen, Qihang Chen, Shurong Zhang, Yajuan Su, Xiaoyi Zou, Ke Wang, Shike Liu, Qian He, Liang Zhang, Weizhu Zeng, Jingwen Zhou   +10 more
wiley   +1 more source

Design of a novel epitope-based tetravalent subunit vaccine against dengue virus: An immunoinformatic approach. [PDF]

PLoS One
Ferdousy TJ, Hasan Miraz MM, Al Arian T, Afif Ullah M, Risat MTH, Akter MA, Kundu S, Sarkar BK, Sarkar AP, Khalipha ABR, Kundu SK.   +10 more
europepmc   +1 more source

An Unbiased Geometry‐Resolved Membrane Platform for Proteome‐Scale Discovery of Membrane Curvature Sensors

Advanced Science, EarlyView.
A novel geometry‐resolved membrane platform provides a seamlessly integrated pipeline for studying curvature‐sensing proteins. By linking shotgun proteomics with quantitative imaging, this approach enables both the unbiased discovery and rigorous validation of novel sensors across the entire curvature range—positive, negative, and zero.
Takumi Komikawa, Rikuto Kawakami, Kunanon Chattrairat, Tatsuya Niwa, Taiga Ajiri, Takao Yasui, Masayoshi Tanaka   +6 more
wiley   +1 more source

Evaluation of Vibrio natriegens as a fast-growing alternative host for plasmid DNA production. [PDF]

Microb Cell Fact
Möller LS, Monteiro GA, Prazeres DMF, Silva-Santos AR.   +3 more
europepmc   +1 more source

Lyssavirus Nucleoprotein Induces GPAT4‐Mediated CYB5R1 Depalmitoylation to Suppress Ferroptosis and Promote Viral Replication

Advanced Science, EarlyView.
Lipid metabolism plays a vital role in viral infections. Here, we reveal that the lyssavirus N protein regulates GPAT4 to induce lipid droplet biogenesis, restricting CYB5R1 palmitoylation and reducing ferroptosis susceptibility to ultimately promote viral replication.
Jianqing Zhao, Chuan Liang, Pingping Chen, Meixin Sun, Zhen F. Fu, Ling Zhao, Ming Zhou   +6 more
wiley   +1 more source

Carbapenem-resistant and other multidrug-resistant organisms in a South Indian tertiary care centre: A laboratory-based study. [PDF]

Indian J Med Res
Kumar AS, Singh SK, John MS, H S, Mohan N, Sebastain IA, S V.   +6 more
europepmc   +1 more source

Detection of bacterial gene expression elements on Tobacco mosaic virus RNA using cDNA analysis. [PDF]

PLoS One
Nishimiya Y.
europepmc   +1 more source

Ligify 2.0: a web server for predicted small molecule biosensors. [PDF]

Nucleic Acids Res
d'Oelsnitz S, Zhao NN, Talla P, Jeong J, Love JD, Springer M, Silver PA.   +6 more
europepmc   +1 more source