Results 261 to 270 of about 184,561 (308)

Whole-organism clone tracing using single-cell sequencing

Nature, 2018
Embryonic development is a crucial period in the life of a multicellular organism, during which limited sets of embryonic progenitors produce all cells in the adult body. Determining which fate these progenitors acquire in adult tissues requires the simultaneous measurement of clonal history and cell identity at single-cell resolution, which has been a
Alemany, Anna, Florescu, Maria, Baron, Chloé S., Peterson-Maduro, Josi, van Oudenaarden, Alexander   +4 more
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The Organization and Evolution of Cloned Globin Genes

1980
The globin genes represent a complex set of sequences that are expressed in a coordinate fashion during the development of red blood cells. while this complex family of genes may consist of as many as ten to fourteen members [34], three of these genes have now been cloned and their entire nucleotide sequence determined. As was initially observed in the
P, Leder, D A, Konkel, Y, Nishioka, A, Leder, D H, Hamer, M, Kaehler   +5 more
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Cloning, expression, and genomic organization of mouse mp29 gene

Biochemical and Biophysical Research Communications, 2002
Human p29 has been demonstrated in the yeast two-hybrid method and in vitro GST pull-down assay to associate with GCIP, a cyclin D interacting protein. In this study, we describe the cloning and genomic structure of the mouse homologue, mp29. The overall mouse mp29 amino acid sequence is highly identical (91%) to human p29.
Mau Sun, Chang, Chiung Ya, Chen, Hung I, Yeh, Chi Chen, Fan, Chang Jen, Huang, Yuh Cheng, Yang   +5 more
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Behavior Cloning by a Self-Organizing Decision Tree

2007 IEEE International Conference on Integration Technology, 2007
It is hard to define a state space or the proper reward function in reinforcement learning to make the robot act as expected. In this paper, we demonstrate the expected behavior for a robot Then a RL-based decision tree approach which decides to split according to long-term evaluations, instead of a top-down greedy strategy which finds out the ...
Kao-Shing Hwang, Yu-Jen Chen, Tsan-Hui Yang   +2 more
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Genetic organization and cloning of kirsten murine sarcoma virus DNA

Biochemical and Biophysical Research Communications, 1982
Summary The Kirsten murine sarcoma virus genome is a recombinant molecule derived from the Kirsten murine leukemia virus genome and sequences transduced from a normal rat cell. We show here that leukemia virus derived sequences comprise the 5′ terminal 0.5 kilobasepairs (kbp) and the 3′ terminal 1.2 kbp of the linear 6.5 kbp sarcoma virus DNA.
J D, Norton, R J, Avery
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Taiwan cobra chymotrypsin inhibitor: cloning, functional expression and gene organization

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2005
A cDNA encoding chymotrypsin inhibitor was constructed from the cellular RNA isolated from the venom glands of Naja atra (Taiwan cobra). The resultant amino acid sequence showed that the mature protein is comprised of 57 amino acid residues with six cysteine residues. Cloned protein was expressed and isolated from the inclusion bodies of E.
Yun-Ching, Cheng, Fang-Jiun, Yan, Long-Sen, Chang   +2 more
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Cloning, Genomic Organization, and Tissue Distribution of Human Ssf-1

Biochemical and Biophysical Research Communications, 2000
During the screening of a human placenta cDNA library, realized in order to isolate the P2Y(11) coding sequence, an unrelated cDNA was cloned. We identified a 1422 bp open reading frame encoding a human protein displaying 40% amino acid identity with the Saccharomyces cerevisiae Ssf-1, a protein involved in the second step of mRNA splicing.
Suarez Gonzalez, Nathalie, Boeynaems, Jean-Marie, Communi, Didier   +2 more
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Gene cloning in organisms other than E. coli.

Current topics in microbiology and immunology, 1982
Cloning Vectors Derived from Plasmids and Phage of Bacillus.- Use of Plasmids from Staphylococcus aureus for Cloning of DNA in Bacillus subtilis.- Vectors for Gene Cloning in Pseudomonas and Their Applications.- Host: Vector Systems for Gene Cloning in Pseudomonas.- Gene Cloning in Streptomyces.- Gene Cloning in Neurospora crassa.- Vectors for Cloning ...
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Implication of therapeutic cloning for organ transplantation.

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2005
Replacement of damaged myocardium with electrically functional, contracting syncytium with a balanced blood supply remains a key goal for the treatment of hearts damaged by coronary heart disease or other disorders. Stem cell therapy offers a potential solution.
J, Hescheler, M, Wartenberg, D, Wenzel, B K W, Roell, Zhongju, Lu, Y, Xia, F, Dönmez, F C, Ling, H, Acker, E, Kolossov, S, Kazemi, P, Sasse, A, Raible, H, Bohlen, W, Bloch, H, Sauer, A, Welz, B K, Fleischmann   +17 more
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Human serine racemase: moleular cloning, genomic organization and functional analysis

Gene, 2000
High levels of D-serine are found in mammalian brain, where it is an endogenous agonist of the strichinine-insensitive site of N-methyl D-aspartate type of glutamate receptors. D-serine is enriched in protoplasmic astrocytes that occur in gray matter areas of the brain and was shown to be synthesized from L-serine.
J, De Miranda, A, Santoro, S, Engelender, H, Wolosker   +3 more
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