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Human allantoicase gene: cDNA cloning, genomic organization and chromosome localization
Gene, 2000Uric-acid-degrading enzymes (uricase, allantoinase, allantoicase, ureidoglycolate lyase and urease) were lost during vertebrate evolution and the causes for this loss are still unclear. We have recently cloned the first vertebrate allantoicase cDNA from the amphibian Xenopus laevis.
VIGETTI, DAVIDE +4 more
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Cloning and Characterization of Two Human Polyspecific Organic Cation Transporters
DNA and Cell Biology, 1997Previously we cloned a polyspecific transporter from rat (rOCT1) that is expressed in renal proximal tubules and hepatocytes and mediates electrogenic uptake of organic cations with different molecular structures. Recently a homologous transporter from rat kidney (rOCT2) was cloned but not characterized in detail. We report cloning and characterization
V, Gorboulev +9 more
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Molecular and Functional Characteristics of Cloned Human Organic Cation Transporters
2005Within the last 5 years the organic cation transport field has moved from tissue and cellular levels to a molecular level of investigation. As we gain a better understanding of the genes and proteins responsible for the multiple mechanisms of organic cation transport, we can begin to apply this knowledge to pharmaceutical and drug discovery research ...
M J, Dresser, L, Zhang, K M, Giacomini
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From organism behaviour to molecular mechanisms
Nature Reviews Molecular Cell Biology, 2021Prachee Avasthi
exaly
EUCARYOTIC GENOME ORGANIZATION: CLONING AND BEYOND
1977Bernard Weisblum, Jerry L. Slightom
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