Results 261 to 270 of about 1,771,671 (365)
Improved methods for genetic manipulation of the alkaliphile Halalkalibacterium halodurans. [PDF]
Front MicrobiolWencker FDR, Lyon SE, Breaker RR.
europepmc +1 more source
Advanced Science, EarlyView.This study develops lipid nanoparticles (LNPs) combining cationic and ionizable lipids for efficient cytosolic protein delivery. Optimized LNPs deliver functional proteins, including antibodies, enzymes, and Cas9, with high serum stability and albumin‐mediated endocytosis.
Lanfang Ren +6 more
wiley +1 more source
Subtractive proteomics and reverse-vaccinology approaches for novel drug targets and designing a chimeric vaccine against <i>Ruminococcus gnavus</i> strain RJX1120. [PDF]
Front ImmunolDingding H +7 more
europepmc +1 more source
Identification and Application of a Novel Patulin Degrading Enzyme From Meyerozyma guilliermondii
Advanced Science, EarlyView.Patulin (PAT), a hazardous mycotoxin, threatens human health. A novel yeast‐derived short‐chain dehydrogenase/reductase effectively degrades PAT into nontoxic ascladiol via catalytic triad activity. The biological detoxification process has no significant effect on the quality of fresh pear juice.
Yu Zhang +7 more
wiley +1 more source
Molecular Diagnostics in the Postgenomic Era. [PDF]
Bioengineering (Basel)Korać P, Matulić M.
europepmc +1 more source
Advanced Science, EarlyView.This study proposes a novel HCC therapy using CA‐4S2@ES‐Cu nanomedicines to amplify cuproptosis, enhancing chemotherapy and immunotherapy. CA‐4 and ES‐Cu synergistically inhibit tumor growth, induce immune responses, and reverse the immunosuppressive microenvironment, offering an effective multidimensional therapeutic strategy for HCC treatment ...
Yingjie Zeng +16 more
wiley +1 more source