Results 21 to 30 of about 169,996 (318)

Effect of Genotype-Guided Oral P2Y12 Inhibitor Selection vs Conventional Clopidogrel Therapy on Ischemic Outcomes After Percutaneous Coronary Intervention: The TAILOR-PCI Randomized Clinical Trial.

Journal of the American Medical Association (JAMA), 2020
Importance After percutaneous coronary intervention (PCI), patients with CYP2C19*2 or *3 loss-of-function (LOF) variants treated with clopidogrel have increased risk of ischemic events.
N. Pereira, M. Farkouh, D. So, R. Lennon, N. Geller, V. Mathew, M. Bell, J. Bae, M. Jeong, Ivan J. Chavez, Paul Gordon, J. Abbott, C. Cagin, L. Baudhuin, Yi-Ping Fu, S. Goodman, S. Goodman, Ahmed A Hasan, E. Iturriaga, A. Lerman, M. Sidhu, J. Tanguay, Liewei Wang, R. Weinshilboum, R. Welsh, Y. Rosenberg, K. Bailey, C. Rihal   +27 more
semanticscholar   +1 more source

Risk of hypoglycemia associated with repaglinide combined with clopidogrel, a retrospective cohort study

Journal of Pharmaceutical Health Care and Sciences, 2020
Background Repaglinide is widely prescribed to reduce postprandial hyperglycemia and elevated glycated hemoglobin (HbA1c) levels associated with type 2 diabetes, and clopidogrel is a thienopyridine antiplatelet agent and widely used in cardiovascular and
Yuuki Akagi, Akiko Iketaki, Haruna Kimura, Yuki Matsudaira, Takami Yoshida, Takahiro Nishimura, Yohei Kawano, Yasunari Mano, Erina Shigematsu, Makoto Ujihara   +9 more
doaj   +1 more source

Clopidogrel-induced pneumonia [PDF]

BMJ Case Reports, 2021
A 75-year-old man was admitted to our hospital with progressive dyspnoea on effort and cough. Three months before presentation, he had undergone percutaneous coronary intervention for unstable angina. At that time, he began taking aspirin (100 mg daily) and clopidogrel (75 mg daily).
Yoshitaka Tomoda, Chinami Nagasawa, Yukikazu Awaya, Takashi Miyajima   +3 more
openaire   +3 more sources

Aspirin with or without Clopidogrel after Transcatheter Aortic-Valve Implantation.

New England Journal of Medicine, 2020
BACKGROUND The effect of single as compared with dual antiplatelet treatment on bleeding and thromboembolic events after transcatheter aortic-valve implantation (TAVI) in patients who do not have an indication for long-term anticoagulation has not been ...
J. Brouwer, V. Nijenhuis, R. Delewi, R. Hermanides, W. Holvoet, C. Dubois, P. Frambach, B. de Bruyne, G. V. van Houwelingen, J. van der Heyden, P. Toušek, F. van der Kley, I. Buysschaert, C. Schotborgh, B. Ferdinande, P. van der Harst, J. Roosen, J. Peper, Frederick W F Thielen, L. Veenstra, D. R. Chan Pin Yin, M. Swaans, B. Rensing, A. W. van ’t Hof, L. Timmers, J. Kelder, P. Stella, J. Baan, J. T. ten Berg   +28 more
semanticscholar   +1 more source

The Role of Genetic Polymorphism and Other Factors on Clopidogrel Resistance (CR) in an Asian Population with Coronary Heart Disease (CHD)

Molecules, 2021
Clopidogrel is a widely-used antiplatelet drug. It is important for the treatment and prevention of coronary heart disease. Clopidogrel can effectively reduce platelet activity and therefore reduce stent thrombosis.
Mohammed Ahmed Akkaif, N. Daud, A. Sha’aban, M. L. Ng, M. A. S. Abdul Kader, D. Noor, B. Ibrahim   +6 more
semanticscholar   +1 more source

Validation of a method for quantitation of the clopidogrel active metabolite, clopidogrel, clopidogrel carboxylic acid, and 2-oxo-clopidogrel in feline plasma [PDF]

Journal of Veterinary Cardiology, 2017
The clopidogrel active metabolite (CAM) is unstable and challenging to quantitate. The objective was to validate a new method for stabilization and quantitation of CAM, clopidogrel, and the inactive metabolites clopidogrel carboxylic acid and 2-oxo-clopiodgrel in feline plasma.Two healthy cats administered clopidogrel to demonstrate assay in vivo ...
Janne G. Lyngby, Michael H. Court, Pamela M. Lee   +2 more
openaire   +3 more sources

Anticoagulation with or without Clopidogrel after Transcatheter Aortic-Valve Implantation.

New England Journal of Medicine, 2020
BACKGROUND The roles of anticoagulation alone or with an antiplatelet agent after transcatheter aortic-valve implantation (TAVI) have not been well studied.
V. Nijenhuis, J. Brouwer, R. Delewi, R. Hermanides, W. Holvoet, C. Dubois, P. Frambach, B. de Bruyne, G. V. van Houwelingen, J. van der Heyden, P. Toušek, F. van der Kley, I. Buysschaert, C. Schotborgh, B. Ferdinande, P. van der Harst, J. Roosen, J. Peper, Frederick W F Thielen, L. Veenstra, D. R. Chan Pin Yin, M. Swaans, B. Rensing, A. W. van ’t Hof, L. Timmers, J. Kelder, P. Stella, J. Baan, J. T. ten Berg   +28 more
semanticscholar   +1 more source

Atorvastatin and Clopidogrel [PDF]

Circulation, 2003
To the Editor: I would like to comment on the recent editorial by Serebruany et al1 in which the study results by Lau et al2 are discussed. It is argued that these results, which are suggestive of a clinically relevant interaction between clopidogrel and atorvastatin, are in conflict with those published previously by Serebruany et al.3 According to ...
openaire   +3 more sources

Clopidogrel and proton pump inhibitor (PPI) interaction: separate intake and a non-omeprazole PPI the solution?

European Journal of Medical Research, 2010
Background Dual therapy with aspirin and clopidogrel increases the risk of gastrointestinal bleeding. Therefore, co-therapy with a proton pump inhibitor (PPI) is recommended by most guidelines.
Kenngott S, Olze R, Kollmer M, Bottheim H, Laner A, Holinski-Feder E, Gross M   +6 more
doaj   +1 more source

Effect of 1-Month Dual Antiplatelet Therapy Followed by Clopidogrel vs 12-Month Dual Antiplatelet Therapy on Cardiovascular and Bleeding Events in Patients Receiving PCI: The STOPDAPT-2 Randomized Clinical Trial.

Journal of the American Medical Association (JAMA), 2019
Importance Very short mandatory dual antiplatelet therapy (DAPT) after percutaneous coronary intervention (PCI) with a drug-eluting stent may be an attractive option.
Hirotoshi Watanabe, T. Domei, T. Morimoto, M. Natsuaki, H. Shiomi, T. Toyota, M. Ohya, S. Suwa, K. Takagi, M. Nanasato, Yoshiki Hata, Masahiro Yagi, N. Suematsu, Takafumi Yokomatsu, I. Takamisawa, M. Doi, T. Noda, H. Okayama, Yoshitane Seino, T. Tada, H. Sakamoto, K. Hibi, M. Abe, K. Kawai, K. Nakao, K. Ando, K. Tanabe, Y. Ikari, K. Hanaoka, Y. Morino, K. Kozuma, K. Kadota, Y. Furukawa, Y. Nakagawa, Takeshi Kimura   +34 more
semanticscholar   +1 more source