Results 51 to 60 of about 169,996 (318)

Outcomes Associated With Clopidogrel-Aspirin Use in Minor Stroke or Transient Ischemic Attack: A Pooled Analysis of Clopidogrel in High-Risk Patients With Acute Non-Disabling Cerebrovascular Events (CHANCE) and Platelet-Oriented Inhibition in New TIA and Minor Ischemic Stroke (POINT) Trials.

open access: yesJAMA Neurology, 2019
Importance Dual antiplatelet therapy with clopidogrel and aspirin is effective for secondary prevention after minor ischemic stroke or transient ischemic attack (TIA).
Yuesong Pan   +13 more
semanticscholar   +1 more source

Comparison Between Ticagrelor and Clopidogrel in Elderly Patients With an Acute Coronary Syndrome

open access: yesCirculation, 2020
Supplemental Digital Content is available in the text. Background: The comparative efficacy and safety of ticagrelor versus clopidogrel in older patients with myocardial infarction (MI) has received limited study.
K. Szummer   +8 more
semanticscholar   +1 more source

Clopidogrel: A multifaceted affair [PDF]

open access: yesThe Journal of Clinical Pharmacology, 2014
AbstractClopidogrel has been the therapy of choice, combined with aspirin, against platelet aggregation in patients at risk of suffering a vascular thrombotic event. Not all patients respond equally to clopidogrel, an observation that has led to searching for a test that, in the clinical setting, could predict patients' “resistance” to therapy.
Antonio Tugores   +1 more
openaire   +4 more sources

Emerging Strategies for Platelet‐Modified Nanoparticles in Targeted Tumor Therapy

open access: yesAdvanced NanoBiomed Research, EarlyView.
This review highlights innovative strategies using platelet‐modified nanoparticles to target tumors more precisely. By mimicking platelet functions, these biomimetic carriers improve tumor homing, enhance drug delivery, and reduce immune clearance.
Chunyu Bai   +5 more
wiley   +1 more source

Clopidogrel in Orthopaedic patients: a review of current practice in Scotland

open access: yesThrombosis Journal, 2007
Background Clopidogrel bisulfate is an antiplatelet agent used to prevent ischaemic events in patients with vascular disease. Current guidelines recommend withholding clopidogrel for 7 days pre-operatively.
Bramley Diane   +2 more
doaj   +1 more source

Influence of genetic polymorphisms in P2Y12 receptor signaling pathway on antiplatelet response to clopidogrel in coronary heart disease

open access: yesBMC Cardiovascular Disorders, 2022
Backgrounds Remarkable interindividual variability in clopidogrel response is observed, genetic polymorphisms in P2RY12 and its signal pathway is supposed to affect clopidogrel response in CHD patients.
Yan-Jiao Zhang   +6 more
doaj   +1 more source

Antiphospholipid Syndrome: An Antibody‐Mediated Disease With Emerging Therapeutic Opportunities

open access: yesArthritis &Rheumatology, EarlyView.
Antiphospholipid syndrome (APS) is an autoimmune thromboinflammatory disease characterized by vascular thrombosis, pregnancy morbidity, and other manifestations driven by antiphospholipid autoantibodies. In this review, we present a clinical case that illustrates some diagnostic and therapeutic challenges in managing severe, relapsing APS ...
Thalia G. Newman, Jason S. Knight
wiley   +1 more source

Upper gastrointestinal lesions in patients receiving clopidogrel anti-platelet therapy

open access: yesJournal of the Formosan Medical Association, 2012
Clopidogrel is associated with a high incidence of upper gastrointestinal bleeding in high-risk patients. However, the characteristic upper gastrointestinal lesions in symptomatic clopidogrel users remain unclear.
Tzung-Jiun Tsai   +14 more
doaj   +1 more source

An Idiosyncratic Reaction to Clopidogrel [PDF]

open access: yesThe Permanente Journal, 2015
Clopidogrel is an irreversible antiplatelet agent belonging to the thienopyridine group that acts to antagonize the adenosine diphosphate P2Y12 receptor on platelets. It thus inhibits the activation of platelet glycoprotein GPIIb/IIIa complex, which is essential for fibrinogen—platelet complex formation.
Kapila, Aaysha   +6 more
openaire   +4 more sources

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