Results 101 to 110 of about 30,781 (201)

GENETICS OF CLOPIDOGREL RESISTANCE: RECENT DATA

, 2015
Antiplatelet therapy is one of the most importance in therapy of patients with injured coronary, cerebral and peripheral arteries. The standard of acute coronary syndrome patients treatment is double antiplatelet therapy: acetylsalicylic acid with ...
D. A. Sychev, K. B. Mirzaev, D. A. Andreev   +2 more
core   +1 more source

Clopidogrel resistance in patients with acute coronary syndrome

Терапевтический архив, 2010
Aim: to reveal the frequency of clopidogrel resistance in patients with acute coronary syndrome (ACS) and its impact on prognosis in these patients. Subjects and methods. Seventy-five clopidogrel-treated patients with ACS were followed up.
N S Frolova, R M Shakhnovich, O V Sirotkina, A B Dobrovolsky, M Ya Ruda   +4 more
doaj  

The development of type 2 diabetes amongst sibling pairs in the South‐South region of Nigeria: The effect of genetics, environment and lifestyle

Diabetic Medicine, Volume 43, Issue 6, June 2026.
Abstract Introduction Type 2 diabetes is a complex condition with a multifactorial pathogenesis. The pathogenesis is considered to be polygenic due to complex interactions between genetic/epigenetic and environmental factors. The aim of this study is to determine the genetic, environmental and lifestyle factors associated with the development of type 2
Sunny Chinenye, Ibi Erekosima, Adrian H. Heald, Gesiye Bozimo, Simon G. Anderson, Samuel Seidu, Kariba Akhidue, Adaeze Ugwu, Chioma Unachukwu, Ibitrokoemi Korubo, Kingsley Chukwuemeka Patrick‐Iwuanyanwu, Victoria Gomba, Uwoma Batubo, Victoria Akanatei, Victor Ken‐Uba, Iyeopu Siminialayi, Sokiprim Akoko, Justin Ideozu, Hamilton Opurum   +18 more
wiley   +1 more source

Sex‐Specific Associations of Inflammatory Biomarkers With All‐Cause and Cardiovascular Mortality Across Glycaemic Status: A Prospective UK Biobank Study

Diabetes, Obesity and Metabolism, Volume 28, Issue 6, Page 4728-4740, June 2026.
ABSTRACT Aims To explore sex‐specific heterogeneity in the prognostic discrimination of inflammatory markers for mortality across different glycaemic states. Methods This prospective cohort study included 450 438 participants from the UK Biobank (median follow‐up: 15.3 years), stratified by sex and glycaemic status.
Yawen Zhang, Menghan Li, Manrong Xu, Yun Shen, Lianxi Li, Gang Hu   +5 more
wiley   +1 more source

The Effect of CYP2C19 and Nongenetic Factors on Clopidogrel Responsiveness in the MENA Region: A Systematic Review

Clinical and Applied Thrombosis/Hemostasis, 2019
Clopidogrel is the cornerstone antiplatelet used in the treatment and prevention of thrombotic events. Some studies examined the effect of CYP2C19 polymorphism and nongenetic factors on clopidogrel response in the Middle East and North Africa (MENA ...
Zainab Ali Msc, Hazem Elewa PhD
doaj   +1 more source

Oral antiplatelet therapy and platelet inhibition: An experience from a tertiary care center

Indian Heart Journal, 2016
Aims and objectives: Although clopidogrel combined with aspirin is the most commonly used dual drug combination to avert thrombotic events in patients with coronary artery disease, the poor responsiveness to clopidogrel remains a concern.
Jamshed J. Dalal, Aarti Digrajkar, Alap Gandhi   +2 more
doaj   +1 more source

Overcoming Clopidogrel Resistance: Discovery of Vicagrel as a Highly Potent and Orally Bioavailable Antiplatelet Agent

, 2016
A series of optically active 2-hydroxytetrahydrothienopyridine derivatives were designed and synthesized as prodrugs of clopidogrel thiolactone in order to overcome clopidogrel resistance. The final compounds were evaluated for their inhibitory effect on
Yanchun Gong (2093536), Fang Yuan (96264), Jiaqi Shan (2093527), Yaoqiu Zhu (1982086), Bo Jiao (1982083), Boyu Zhang (354009), Fusheng Lv (2093533), Hongbin Sun (113935), Weiyi Zheng (2093530), Xiaowei Qi (1677340)   +9 more
core   +1 more source

Multiple Recurrent Stent Thrombosis in a Patient with Coexisting Clopidogrel Resistance and Increased Anticardiolipin Antibodies: A Case Report

Case Reports in Medicine, 2010
The antiphospholipid syndrome (APS) is a common cause of both arterial and venous thrombosis. While studies exist demonstrating the role of APS in coronary artery bypass graft failure, its role in stent thrombosis is less clearly documented.
Erik H. Middlebrooks, Mukta Panda
doaj   +1 more source

Effect of proton pump inhibitors on platelet inhibition activity of clopidogrel in Chinese patients with percutaneous coronary intervention

Vascular Health and Risk Management, 2011
Joanne Kwan1, Wah Wah Htun2, Yili Huang3, Wilson Ko3, Tak W Kwan31Boston University, Boston, MA, USA; 2Lutheran Medical Center, Brooklyn, NY, USA; 3Beth Israel Medical Center, New York, NY, USABackground: The purpose of this study was to examine the ...
Kwan T, Kwan, Huang, Htun, Ko
doaj  

CYP2C19*2 polymorphism and clopidogrel resistance [PDF]

Archivos de cardiolog�a de M�xico (English ed. Internet), 2021
Beuy, Joob, Viroj, Wiwanitkit
openaire   +2 more sources