Results 111 to 120 of about 39,017 (214)

Clopidogrel resistance in patients with acute coronary syndrome

open access: yesТерапевтический архив, 2010
Aim: to reveal the frequency of clopidogrel resistance in patients with acute coronary syndrome (ACS) and its impact on prognosis in these patients. Subjects and methods. Seventy-five clopidogrel-treated patients with ACS were followed up.
N S Frolova   +4 more
doaj  

Effects of the atorvastatin and clopidogrel combination therapy on statin bioavailability and platelet function of patients with stable coronary disease [PDF]

open access: yes, 2010
BACKGROUND: Atorvastatin 80 mg is recommended in patients with coronary artery disease to reduce cardiovascular events, however, there is controversy regarding the pharmacokinetic interactions between high doses of statins and the concomitant use of ...
Barbosa, Simone Pinto de Melo   +12 more
core   +2 more sources

Serotonin reuptake inhibitors and cardiovascular disease [PDF]

open access: yes, 2005
Selective serotonin re-uptake inhibiting drugs (SSRIs) are widely used for endogenous depression. In addition to depleting the nerve terminals of serotonin they also lower blood platelet serotonin levels.
Belcher, P.R.   +2 more
core   +1 more source

Aspirin and clopidogrel resistance: methodological challenges and opportunities

open access: yesVascular Health and Risk Management, 2010
Armen Yuri GasparyanClinical Research Unit, Russell’s Hall Hospital, Dudley Group of Hospitals NHS Foundation Trust, West Midlands, UKAbstract: Antiplatelet drug resistance is one of the urgent issues in current cardiovascular medicine.
Armen Yuri Gasparyan
doaj  

The Effect of CYP2C19 and Nongenetic Factors on Clopidogrel Responsiveness in the MENA Region: A Systematic Review

open access: yesClinical and Applied Thrombosis/Hemostasis, 2019
Clopidogrel is the cornerstone antiplatelet used in the treatment and prevention of thrombotic events. Some studies examined the effect of CYP2C19 polymorphism and nongenetic factors on clopidogrel response in the Middle East and North Africa (MENA ...
Zainab Ali Msc, Hazem Elewa PhD
doaj   +1 more source

Oral antiplatelet therapy and platelet inhibition: An experience from a tertiary care center

open access: yesIndian Heart Journal, 2016
Aims and objectives: Although clopidogrel combined with aspirin is the most commonly used dual drug combination to avert thrombotic events in patients with coronary artery disease, the poor responsiveness to clopidogrel remains a concern.
Jamshed J. Dalal   +2 more
doaj   +1 more source

A Pilot Study of Value of Information Analysis to Support Research Recommendations for the National Institute for Health and Clinical Excellence [PDF]

open access: yes
Background - This project developed as a result of the activities of the Research Teams at the Centre for Health Economics, University of York, and ScHARR at the University of Sheffield in the methods and application of decision analysis and value of ...
Alan Wailoo   +7 more
core  

Multiple Recurrent Stent Thrombosis in a Patient with Coexisting Clopidogrel Resistance and Increased Anticardiolipin Antibodies: A Case Report

open access: yesCase Reports in Medicine, 2010
The antiphospholipid syndrome (APS) is a common cause of both arterial and venous thrombosis. While studies exist demonstrating the role of APS in coronary artery bypass graft failure, its role in stent thrombosis is less clearly documented.
Erik H. Middlebrooks, Mukta Panda
doaj   +1 more source

Effect of proton pump inhibitors on platelet inhibition activity of clopidogrel in Chinese patients with percutaneous coronary intervention

open access: yesVascular Health and Risk Management, 2011
Joanne Kwan1, Wah Wah Htun2, Yili Huang3, Wilson Ko3, Tak W Kwan31Boston University, Boston, MA, USA; 2Lutheran Medical Center, Brooklyn, NY, USA; 3Beth Israel Medical Center, New York, NY, USABackground: The purpose of this study was to examine the ...
Kwan T, Kwan, Huang, Htun, Ko
doaj  

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