Results 91 to 100 of about 30,781 (201)
Stent thrombosis (ST) is considered as a multifactorial problem which is mostly occurs due to clopidogrel resistance. It may be due to some CYP450 enzyme deficiencies which play role in clopidogrel metabolism. Therefore the aim of this study is to detect
GÜNEY, AHMET İLTER
core +2 more sources
ABSTRACT Background Unfractionated heparin (UFH) remains the standard anticoagulant during percutaneous coronary intervention (PCI), with guidelines recommending a target activated clotting time (ACT) of ≥250 s. However, despite receiving a standardized bolus dose, many patients fail to achieve this target.
Manh Cuong Vu +9 more
wiley +1 more source
ABSTRACT Severe coronary calcification is a common challenge in percutaneous coronary intervention, often resulting in suboptimal stent expansion. Intravascular lithotripsy (IVL) employs acoustic pressure waves to fracture calcified plaques and increase procedural success.
Liang‐cai Guo +3 more
wiley +1 more source
ABSTRACT Background High‐intensity statins are standard therapy after percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS), yet tolerability concerns and residual cardiovascular risk remain important challenges. Moderate‐intensity statin therapy combined with ezetimibe has emerged as a potential alternative, although its ...
Emad Uddin Sajid +12 more
wiley +1 more source
The final flowchart categorizes subjects into two groups: the control group (n = 60) undergoing OPCABG alone and the combined cardiocerebrovascular revascularization group (n = 57). ABSTRACT Objectives The impact of simultaneous coronary artery bypass grafting (CABG) with cerebral revascularization versus CABG alone on perioperative complications and ...
Bo Li +10 more
wiley +1 more source
BACKGROUND: Clopidogrel is a widely used antithrombotic agent that inhibits the platelet P2Y(12) adenosine diphosphate (ADP) receptor. There is increasing interest in 'clopidogrel resistance'.
Frelinger, Andrew L. III +8 more
core +1 more source
Prevalence of clopidogrel resistance evaluated by the VASP method
BACKGROUND: Despite oral antiplatelet treatment a certain number of patients suffer adverse events while on therapy. Whether patients demonstrating low platelet inhibition in vitro are at increased risk for adverse events is unknown.
Dahl, Karine Haug
core
Clopidogrel is a prodrug that has to be converted to an active metabolite by hepatic cytochrome P450 (CYP) isoenzymes to inhibit platelet aggregation. Individual variability of platelet inhibition by clopidogrel suggests a possibility for genetic factors
이정명 +6 more
core +1 more source
Effect of original and generic clopidogrel on prognosis in relation to different gene polymorphisms
AIM. To analyze the influence of clinical and pharmacogenetic factors on the risk of resistance to original or generic clopidogrel and that of cardiovascular events (CVE) during 12 months of follow-up. MATERIALS AND METHODS.
D F Mesitskaia +4 more
doaj
ABSTRACT Background and Aim In an aging population, stroke is a leading cause of morbidity and mortality. More than 80% of stroke cases in the elderly are ischemic strokes. Stroke is the sixth most common cause of disability globally and the second most common cause after ischemic heart disease (IHD).
Sohailuddin Mohammad +10 more
wiley +1 more source

