Results 91 to 100 of about 2,233,111 (188)

Table_1_Comparison of Clopidogrel and Ticlopidine/Ginkgo Biloba in Patients With Clopidogrel Resistance and Carotid Stenting.docx

, 2019
Background and Purpose: Patients undergoing carotid artery stenting (CAS) who show low responsiveness to clopidogrel may have a higher risk of peri-procedural embolic events.
Oh Young Bang (135041), Mi Ji Lee (2813992), Man-Seok Park (112585), Jun Lee (36618), Kyung-Yul Lee (6093818), Jong-Won Chung (2813989), Suk Jae Kim (135028), Sang Min Sung (6275354), Pyoung Jeon (763023), Jaechun Hwang (6275351), Keon Ha Kim (763021)   +10 more
core   +1 more source

Is Preoperative Clopidogrel Resistance a Predictor of Bleeding and Risks in Patients Undergoing Emergency CABG Surgery?

Brazilian Journal of Cardiovascular Surgery
Objective: The aims of this study were to determine whether the detection of preoperative clopidogrel resistance in patients undergoing cardiac surgery while using clopidogrel could play a guiding role in the prediction of postoperative excessive ...
Mehmet Kizilay, Zeynep Aslan, Unsal Vural, Ahmet Yavuz Balci, Ahmet Arif Aglar, Sahin Yilmaz   +5 more
doaj   +1 more source

Effect of original and generic clopidogrel on prognosis in relation to different gene polymorphisms

Терапевтический архив, 2014
AIM. To analyze the influence of clinical and pharmacogenetic factors on the risk of resistance to original or generic clopidogrel and that of cardiovascular events (CVE) during 12 months of follow-up. MATERIALS AND METHODS.
D F Mesitskaia, Iu M Nikitina, O V Lomakin, D Iu Shchekochikhin, F Iu Kopylov   +4 more
doaj  

GENETICS OF CLOPIDOGREL RESISTANCE: RECENT DATA [PDF]

, 2015
Antiplatelet therapy is one of the most importance in therapy of patients with injured coronary, cerebral and peripheral arteries. The standard of acute coronary syndrome patients treatment is double antiplatelet therapy: acetylsalicylic acid with ...
D. A. Sychev, K. B. Mirzaev, D. A. Andreev   +2 more
core   +1 more source

Clopidogrel resistance in patients with acute coronary syndrome

Терапевтический архив, 2010
Aim: to reveal the frequency of clopidogrel resistance in patients with acute coronary syndrome (ACS) and its impact on prognosis in these patients. Subjects and methods. Seventy-five clopidogrel-treated patients with ACS were followed up.
N S Frolova, R M Shakhnovich, O V Sirotkina, A B Dobrovolsky, M Ya Ruda   +4 more
doaj  

The Effect of CYP2C19 and Nongenetic Factors on Clopidogrel Responsiveness in the MENA Region: A Systematic Review

Clinical and Applied Thrombosis/Hemostasis, 2019
Clopidogrel is the cornerstone antiplatelet used in the treatment and prevention of thrombotic events. Some studies examined the effect of CYP2C19 polymorphism and nongenetic factors on clopidogrel response in the Middle East and North Africa (MENA ...
Zainab Ali Msc, Hazem Elewa PhD
doaj   +1 more source

Supranational surveillance of antimicrobial resistance: The legacy of the last decade and proposals for the future

, 2010
Antimicrobial resistance among clinically important bacteria is widely acknowledged as a major global public health threat. A decade ago, several supranational surveillance initiatives were introduced. Few of them are still ongoing, and only one features
CORNAGLIA, Giuseppe, Giske CG, European Study Group on Antimicrobial Resistance Surveillance   +2 more
core   +1 more source

Multiple Recurrent Stent Thrombosis in a Patient with Coexisting Clopidogrel Resistance and Increased Anticardiolipin Antibodies: A Case Report

Case Reports in Medicine, 2010
The antiphospholipid syndrome (APS) is a common cause of both arterial and venous thrombosis. While studies exist demonstrating the role of APS in coronary artery bypass graft failure, its role in stent thrombosis is less clearly documented.
Erik H. Middlebrooks, Mukta Panda
doaj   +1 more source

Evidence that pre-existent variability in platelet response to ADP accounts for 'clopidogrel resistance'

, 2012
BACKGROUND: Clopidogrel is a widely used antithrombotic agent that inhibits the platelet P2Y(12) adenosine diphosphate (ADP) receptor. There is increasing interest in 'clopidogrel resistance'.
Frelinger, Andrew L. III, Lau, W. C., Barnard, Marc R., Linden, Matthew Dean, Furman, Mark I., Fox, Marsha L., Michelson, Alan D., Li, YouFu, McLaughlin, Thomas J.   +8 more
core   +1 more source

Relation of genetic polymorphisms in the cytochrome P450 gene with clopidogrel resistance after drug-eluting stent implantation in Koreans

, 2009
Clopidogrel is a prodrug that has to be converted to an active metabolite by hepatic cytochrome P450 (CYP) isoenzymes to inhibit platelet aggregation. Individual variability of platelet inhibition by clopidogrel suggests a possibility for genetic factors
이정명, 최동훈, 박성하, 김중선, 심지영, 장양수, 고영국   +6 more
core   +1 more source