Effect of original and generic clopidogrel on prognosis in relation to different gene polymorphisms
AIM. To analyze the influence of clinical and pharmacogenetic factors on the risk of resistance to original or generic clopidogrel and that of cardiovascular events (CVE) during 12 months of follow-up. MATERIALS AND METHODS.
D F Mesitskaia +4 more
doaj
Clopidogrel resistance in patients with ST-elevation myocardial infarction is associated with high body mass index [PDF]
Ingebjørg Seljeflot +5 more
openalex +1 more source
The importance of tests applied to evaluate the effectiveness of antiplatelet therapy in patients with recurrent coronary stent thrombosis [PDF]
Background. Stent thrombosis is potentially lethal complication with huge economic burden. The role of insufficient response to antiplatelet therapy is still unclear reason for its occurrence. Case report.
Cikota Bojana +10 more
core +1 more source
Association of clopidogrel resistance with ethnicity in Pakistan.
Nawaz Usman +5 more
openalex +2 more sources
Clopidogrel resistance in patients with acute coronary syndrome
Aim: to reveal the frequency of clopidogrel resistance in patients with acute coronary syndrome (ACS) and its impact on prognosis in these patients. Subjects and methods. Seventy-five clopidogrel-treated patients with ACS were followed up.
N S Frolova +4 more
doaj
Clopidogrel Pharmacogenetics, resistance to antiplatelet therapy in ischemic stroke by Epigenome Wide Association Study (EWAS). [PDF]
Curs 2012-2013Clopidogrel is a widely used antiplatelet drug used in preventing vascular events after suffering a first stoke. Genome-wide association studies (GWAS) has not been able to establish a clear association between polymorphisms and recurrence.
Gallego Fàbrega, Cristina
core
Oral antiplatelet therapy and platelet inhibition: An experience from a tertiary care center
Aims and objectives: Although clopidogrel combined with aspirin is the most commonly used dual drug combination to avert thrombotic events in patients with coronary artery disease, the poor responsiveness to clopidogrel remains a concern.
Jamshed J. Dalal +2 more
doaj +1 more source
Role of Cytochrome p450 in Clopidogrel Resistance in Indonesian Stroke Patients
Rakhmad Hidayat +8 more
openalex +2 more sources
Aspirin and clopidogrel resistance: methodological challenges and opportunities
Armen Yuri GasparyanClinical Research Unit, Russell’s Hall Hospital, Dudley Group of Hospitals NHS Foundation Trust, West Midlands, UKAbstract: Antiplatelet drug resistance is one of the urgent issues in current cardiovascular medicine.
Armen Yuri Gasparyan
doaj
Clopidogrel is the cornerstone antiplatelet used in the treatment and prevention of thrombotic events. Some studies examined the effect of CYP2C19 polymorphism and nongenetic factors on clopidogrel response in the Middle East and North Africa (MENA ...
Zainab Ali Msc, Hazem Elewa PhD
doaj +1 more source

