Clopidogrel Resistance in Ischemic Stroke Patients. [PDF]
Ann Indian Acad NeurolStroke remained the second leading cause of death globally in 2019. The antiplatelet drug clopidogrel is used to keep blood clots from forming in people who have experienced a stroke. Although most people find clopidogrel to be safe and beneficial, there is inevitably a range in how each patient responds.
Lavanya S +4 more
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Clopidogrel resistance: The way forward
Indian Heart Journal, 2014 Clopidogrel, a second generation thienopyridine has been the mainstay of ACS (Acute Coronary Syndrome) treatment for more than a decade. Clopidogrel Resistance has been associated with increased mortality in ACS patients with an increase in number of ...
Shuvanan Ray
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Abstract 078: Managing Clopidogrel Resistance in Neurointervention: Surveying Current Approaches
Stroke: Vascular and Interventional Neurology, 2023 Introduction Due to the variability in patient responses to clopidogrel, adjusting antiplatelet regimen based on platelet function testing has become a widespread practice to reduce thromboembolic complications in neurointervention.
Hyun Woo Kim +6 more
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Managing Clopidogrel Resistance in Neurointervention: Surveying Current Approaches [PDF]
Stroke: Vascular and Interventional NeurologyBackground Because of the variability in patient responses to clopidogrel and to reduce the risk of thromboembolic complications, adjusting the antiplatelet regimen based on platelet function testing has become a widespread practice in neurointervention.
Hyun Woo Kim +7 more
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Cyp2C19*2 Polymorphism Related to Clopidogrel Resistance in Patients With Coronary Heart Disease, Especially in the Asian Population: A Systematic Review and Meta-Analysis [PDF]
Frontiers in Genetics, 2020 In recent years, the relationship between Cyp2C19*2 gene polymorphism and clopidogrel resistance reflected by platelet function assay has been studied extensively, but there is no clear conclusion yet.
Ying Sun +4 more
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Clopidogrel resistance and genetic factors
Türk Kardiyoloji Derneği Arşivi, 2013 Dual antiplatelet therapy combining aspirin and clopidogrel is the standart care for patients WHO ave ACS or undergoing PCI according to guidelines.Itss well established that the antiplatelet response to clopidogrel varies widely among patients.Patients ...
Alev Arat Özkan
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The Correlation Between MDR1 Gene Polymorphism and Clopidogrel Resistance in People of the Hui and Han Nationalities. [PDF]
Clin Appl Thromb Hemost, 2022 Zhang J +5 more
europepmc +3 more sources
Comparison of Clopidogrel and Ticlopidine/Ginkgo Biloba in Patients With Clopidogrel Resistance and Carotid Stenting [PDF]
Frontiers in Neurology, 2019 Background and Purpose: Patients undergoing carotid artery stenting (CAS) who show low responsiveness to clopidogrel may have a higher risk of peri-procedural embolic events.
Jong-Won Chung +10 more
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Aspirin and Clopidogrel Resistance [PDF]
Mayo Clinic Proceedings, 2006 Despite aspirin's and clopidogrel's proven benefit in reducing cardiovascular (CV) events, recurrent CV events still occur in patients receiving antiplatelet therapy. Many of these patients are resistant or only partially responsive to the antiplatelet effects of aspirin and clopidogrel, as determined by standard platelet assays.
Daniel Fosburgh
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Clopidogrel “resistance” [PDF]
Thrombosis and Haemostasis, 2004 Although platelets lack nuclei and are the smallest circulating human cells, they play an integral and complex role in the process of thrombosis, both physiological and pathophysiological. Activation and aggregation of platelets play a central role in the propagation of intracoronary thrombi after (1) spontaneous atherosclerotic plaque disruption that ...
Karsten, Schrör +2 more
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