Results 31 to 40 of about 971 (151)
Resistance to clopidogrel: A review of the evidence
Current available data show that about 4% to 30% of patients treated with conventional doses of clopidogrel do not display adequate antiplatelet response. Clopidogrel resistance is a widely used term that remains to be clearly defined. So far, it has been used to reflect failure of clopidogrel to achieve its antiaggregatory effect.
Thuy Anh Nguyen+2 more
openaire +3 more sources
Abstract 078: Managing Clopidogrel Resistance in Neurointervention: Surveying Current Approaches
Introduction Due to the variability in patient responses to clopidogrel, adjusting antiplatelet regimen based on platelet function testing has become a widespread practice to reduce thromboembolic complications in neurointervention.
Hyun Woo Kim+6 more
doaj +1 more source
Can We Override Clopidogrel Resistance? [PDF]
Clopidogrel, a thienopyridine antiplatelet agent, has been used alone or in association with aspirin to prevent vascular complications in atherothrombotic patients. It is also, in combination with aspirin, the key treatment to prevent stent thrombosis in patients who have undergone percutaneous coronary intervention.
Jean-Sébastien Hulot+7 more
openaire +3 more sources
Rakhmad Hidayat,1– 3 Al Rasyid,2,3 Salim Harris,2,3 Alida Harahap,2 Herqutanto,2 Melva Louisa,2 Erlin Listiyaningsih,4 Aldy Safruddin Rambe,5 Tonny Loho6 1Doctoral Program in Medical Sciences Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia;
Hidayat R+8 more
doaj
Diabetes mellitus and clopidogrel “resistance”
In our Department arrives a 75-year-old patient with hypertension, diabetes mellitus (DM) treated with hypoglycaemic drugs, dyslipidaemia and ischaemic heart disease post-acute myocardial infarction treated with triple coronary artery bypass surgery and subsequent percutaneous transluminal coronary angioplasty (PTCA).
Massarelli, Laura+3 more
openaire +4 more sources
Clopidogrel “Resistance”: Where are We Now? [PDF]
SUMMARYAntiplatelet therapy with aspirin and clopidogrel in PCI patients, though effective, is still associated with thrombotic complications. These are multifactorial in origin, but partially attributable to “clopidogrel resistance.” However, how best to identify and manage “clopidogrel resistance” remains unclear.
Zeshan Qureshi, Alex Hobson
openaire +3 more sources
Clopidogrel, a drug belonging to the thienopyridine class of antiplatelet agents, has been utilized either as a standalone medication or in combination with aspirin for averting vascular complications in patients afflicted with atherothrombotic conditions.
B. V. Raghavendra+4 more
openaire +1 more source
Objective – to study the result of light transmission aggregometry with ADP for platelet reactivity before and after clopidogrel administration before extra-intracranial stenting. Materials and methods.
D.V. Shchehlov+3 more
doaj +1 more source
Clopidogrel resistance — The cardiologist's perspective
Platelet activation and aggregation play a major role in the pathogenesis of acute coronary syndromes. While clopidogrel has convincingly been shown to reduce atherothrombotic events in patients with acute coronary syndromes, and following percutaneous coronary interventions (PCI), a significant portion of patients continue to suffer cardiovascular ...
Shlomi Matetzky, Hanoch Hod, Paul Fefer
openaire +3 more sources
Ilaprazole and Clopidogrel Resistance in Acute Stroke Patients
Clopidogrel, an antiplatelet agent used for secondary prevention of cerebrovascular diseases, is often taken with proton pump inhibitors (PPIs). Generally, the combined use of clopidogrel and PPIs causes adverse drug–drug interactions. VerifyNow is a quick and convenient method to confirm clopidogrel resistance (CR), which compromises adequate ...
In Hwan Lim+3 more
openaire +3 more sources