Results 51 to 60 of about 943 (131)
ABSTRACT Background The utility of hematological ratios in immune‐mediated hemolytic anemia (IMHA) in dogs has seldom been investigated. Hypothesis Hematological ratios are associated with disease severity and outcome in dogs with IMHA. Animals Two hundred and six client‐owned dogs with non‐associative IMHA.
Antoine A. Duclos+6 more
wiley +1 more source
Contribution of Hepatic Cytochrome P450 3A4 Metabolic Activity to the Phenomenon of Clopidogrel Resistance [PDF]
Wei C. Lau+8 more
openalex +3 more sources
A study on the impact of CYP2C19 genotype and platelet reactivity assay on patients undergoing PCI
Background: A thorough understanding of the patient's genotype and their functional response to a medication is necessary for improving event free survival.
P.C. Rath+9 more
doaj +1 more source
Immunoregulatory mechanisms of the arachidonic acid pathway in cancer
The central role of the arachidonic acid (AA) pathway in anticancer immunity. Enzymes and metabolites of the AA pathway can play both immunosuppressive and immunostimulatory roles in the tumor microenvironment. Therefore, their tailored targeting could be beneficial as a standalone therapy or in combination with current cancer immunotherapy.
Maria Tredicine+3 more
wiley +1 more source
Objective: The aims of this study were to determine whether the detection of preoperative clopidogrel resistance in patients undergoing cardiac surgery while using clopidogrel could play a guiding role in the prediction of postoperative excessive ...
Mehmet Kizilay+5 more
doaj +1 more source
Effect of original and generic clopidogrel on prognosis in relation to different gene polymorphisms
AIM. To analyze the influence of clinical and pharmacogenetic factors on the risk of resistance to original or generic clopidogrel and that of cardiovascular events (CVE) during 12 months of follow-up. MATERIALS AND METHODS.
D F Mesitskaia+4 more
doaj
Clopidogrel resistance and genetic factors
Dual antiplatelet therapy combining aspirin and clopidogrel is the standart care for patients WHO ave ACS or undergoing PCI according to guidelines.Itss well established that the antiplatelet response to clopidogrel varies widely among patients.Patients ...
Alev Arat Özkan
doaj +1 more source
Clopidogrel resistance in patients with acute coronary syndrome
Aim: to reveal the frequency of clopidogrel resistance in patients with acute coronary syndrome (ACS) and its impact on prognosis in these patients. Subjects and methods. Seventy-five clopidogrel-treated patients with ACS were followed up.
N S Frolova+4 more
doaj
Background and Purpose: Patients undergoing carotid artery stenting (CAS) who show low responsiveness to clopidogrel may have a higher risk of peri-procedural embolic events.
Jong-Won Chung+10 more
doaj +1 more source
The Role of Genetic Polymorphism and Other Factors on Clopidogrel Resistance (CR) in an Asian Population with Coronary Heart Disease (CHD) [PDF]
Mohammed Ahmed Akkaif+6 more
openalex +1 more source