Clostridioides difficile Flagella
International Journal of Molecular SciencesClostridioides difficile is an important pathogen for humans with a lead in nosocomial infection, but it is also more and more common in communities. Our knowledge of the pathology has historically been focused on the toxins produced by the bacteria that remain its major virulence factors.
Jean-Christophe Marvaud +3 more
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Antibiotics, 2019 Background: Oral vancomycin is a first line treatment for an initial episode of Clostridioides difficile infection. However, the comparative efficacy of different dosing regimens is lacking evidence in the current literature. Methods: We searched PubMed,
Chia-Yu Chiu +3 more
doaj +1 more source
Identification of a Novel Regulator of Clostridioides difficile Cortex Formation
mSphere, 2021 The Centers for Disease Control has designated Clostridioides difficileC.
Megan H. Touchette +6 more
doaj +1 more source
Dietary Prebiotics Modulate Omeprazole‐Induced Alterations in the Gut Microbial Signature
Molecular Nutrition &Food Research, EarlyView.Dietary prebiotic sources such as blueberries and strawberries may help improve proton pump inhibitor (PPI)‐induced gut dysbiosis. These berries represent a promising nutritional strategy for mitigating PPI‐associated gut dysbiosis and inflammation. ABSTRACT Proton pump inhibitors (PPIs) are commonly used to treat heartburn and acid‐related disorders ...
Molly Jenee Buccola +11 more
wiley +1 more source
Response: Commentary: Probing Genomic Aspects of the Multi-Host Pathogen Clostridium perfringens Reveals Significant Pangenome Diversity, and a Diverse Array of Virulence Factors [PDF]
, 1998 Official Student Newspaper Issue is 20 pages ...
Hall, Lindsay J., Kiu, Raymond
core +20 more sources
Expanding Our Grasp of Two-Component Signaling in \u3ci\u3eClostridioides difficile\u3c/i\u3e [PDF]
, 2023 The intestinal pathogen Clostridioides difficile encodes roughly 50 TCS, but very few have been characterized in terms of their activating signals or their regulatory roles. A. G. Pannullo, B. R. Zbylicki, and C. D. Ellermeier (J Bacteriol 205:e00164-23,
Alvarez, Orlando Berumen +1 more
core +1 more source
mSphere, 2021 Diarrheal samples from patients taking laxatives are typically rejected for Clostridioides difficileC ...
Sarah Tomkovich +9 more
doaj +1 more source
Whole genome metagenomic analysis of the gut microbiome of differently fed infants identifies differences in microbial composition and functional genes, including an absent CRISPR/Cas9 gene in the formula-fed cohort [PDF]
, 2019 Background: Advancements in sequencing capabilities have enhanced the study of the human microbiome. There are limited studies focused on the gastro-intestinal (gut) microbiome of infants, particularly the impact of diet between breast-fed (BF) versus ...
Cox, Courtney +3 more
core +2 more sources
Imaging of Abdominal Complications in Children With Acute Lymphoblastic Leukaemia
Journal of Medical Imaging and Radiation Oncology, EarlyView.ABSTRACT Acute lymphoblastic leukaemia (ALL) is the most common paediatric malignancy and remains one of the most common causes of cancer‐related death in children and adolescents. Five‐year overall survival rates now exceed 90% with current multidrug chemotherapeutic regimens. This improvement, coupled with the toxicity of chemotherapy, has led to the
Luke R. Holmes +2 more
wiley +1 more source
Clostridioides difficile: A diagnostic intervention
Antimicrobial Stewardship & Healthcare Epidemiology, 2022 Background:Clostridioides difficile infection (CDI) is a leading cause of healthcare-associated infection and is associated with increased morbidity and mortality. Multiple strategies have been implemented to optimize the diagnostic accuracy of CDI testing algorithms. However, overdiagnosis of C. difficile colonization remains a challenge especially in
Majd Alsoubani +3 more
openaire +2 more sources