Results 81 to 90 of about 194,027 (161)

Clostridium difficile has a single sortase, SrtB, that can be inhibited by small-molecule inhibitors. [PDF]

, 2014
BACKGROUND: Bacterial sortases are transpeptidases that covalently anchor surface proteins to the peptidoglycan of the Gram-positive cell wall. Sortase protein anchoring is mediated by a conserved cell wall sorting signal on the anchored protein ...
Valiente, Esmeralda, Donahue, Elizabeth H, Major, Meriel R, Perrior, Trevor R, Firth-Clark, Stuart, Dawson, Lisa F, Littler, Eddy, Wren, Brendan W   +7 more
core   +1 more source

Examination of the Prevalence, Genetic Diversity and Antibiotic Resistance of Clostridium Difficile (Clostridioides difficile) in Semi-Cooked Ready-to-Eat Products in the Sale Centers of Isfahan Province, Iran [PDF]

تحقیقات نظام سلامت
Background: Clostridium difficile (Clostridioides difficile) is known as one of the main causes of pseudomembranous colitis and is considered an important enteropathogen in humans.
Parvin Ghorbani, Ebrahim Rahimi, Amir Shakerian, Zahra Esfandiari   +3 more
doaj  

Elucidating human gut microbiota interactions that robustly inhibit diverse Clostridioides difficile strains across different nutrient landscapes

Nature Communications
The human gut pathogen Clostridioides difficile displays substantial inter-strain genetic variability and confronts a changeable nutrient landscape in the gut. We examined how human gut microbiota inter-species interactions influence the growth and toxin
Jordy Evan Sulaiman, Jaron Thompson, Yili Qian, Eugenio I. Vivas, Christian Diener, Sean M. Gibbons, Nasia Safdar, Ophelia S. Venturelli   +7 more
doaj   +1 more source

Incidence of Clostridioides difficile infection at a Saudi Tertiary Academic Medical Center and compliance with IDSA/SHEA, ACG, and ESCMID guidelines for treatment over a 10-year period

Journal of Infection and Public Health, 2020
Background: Limited data currently exist on the incidence of Clostridioides difficile infection (CDI) in Saudi Arabia. Compliance with CDI treatment guidelines is prudent for proper management of the infection and preventing recurrence. Methods: This was
Nouf A. Aljafel, Hadeel H. Al-Shaikhy, Maram A. Alnahdi, Abrar K. Thabit   +3 more
doaj   +1 more source

Inflammatory Bowel Disease: Mechanisms and Therapeutic Advances

MedComm, Volume 7, Issue 9, September 2026.
Inflammatory bowel disease (IBD), encompassing ulcerative colitis and Crohn's disease, is a rising, multifactorial chronic disorder driven by dysregulated mucosal immunity in genetically susceptible individuals and influenced by environmental and microbial factors.
Andrea Papait, Anna Cargnoni, Franco Scaldaferri, Loris Lopetuso, Antonietta Rosa Silini, Ornella Parolini   +5 more
wiley   +1 more source

Microbial Signals in Cancer: Dissecting Host–Microbiota–Tumor Interactions and Potential Therapeutic Strategy

MedComm, Volume 7, Issue 9, September 2026.
Microbial signals from gut and tumor‐resident bacteria, fungi, viruses, and bacteriophages reshape immune and metabolic networks within the tumor microenvironment, thereby influencing cancer progression, treatment response. Therapeutic modulations, including dietary interventions, probiotics, antibiotics, fecal microbiota transplantation, engineered ...
Juan Lu, Mengjuan Xuan, Liang Yu, Zhongyang Xie, Qingfei Chu, Shihui Wei, Tuokai Wang, Chen Xue, Lanjuan Li   +8 more
wiley   +1 more source

Ausbruchsuntersuchungen bei Clostridium (Clostridioides) difficile [PDF]

, 2018
Clostridium difficile (neue Taxonomie Clostridioides difficile) kann neben leichten klinischen Verläufen auch schwerwiegende Infektionen verursachen. Im Krankenhausumfeld und anderen Einrichtungen des Gesundheitswesens, aber auch Alten- und Pflegeheimen ...
Gärtner, Barbara, Berger, Fabian, Mellmann, Alexander, Müller, Lutz von   +3 more
core   +1 more source

Structural and Functional Insights into the Delivery Systems of Bacillus and Clostridial Binary Toxins

Toxins
Pathogenic Bacillus and clostridial (i.e., Clostridium and Clostridioides) bacteria express a diverse repertoire of effector proteins to promote disease.
Spiridon E. Sevdalis, Kristen M. Varney, Mary E. Cook, Joseph J. Gillespie, Edwin Pozharski, David J. Weber   +5 more
doaj   +1 more source

Clostridioides difficile (formerly known as Clostridium difficile) [PDF]

Clostridioides difficile (also known as C. diff ) is a bacterium that causes diarrhea and colitis (an inflammation of the colon). C. diff infection can be life-threatening.CS316107-APublication date from document properties.Cdiff-Factsheet-P ...

core  

National Surveillance for Clostridioides difficile Infection, Sweden, 2009–2016

Emerging Infectious Diseases, 2018
We report results from a national surveillance program for Clostridioides difficile infection (CDI) in Sweden, where CDI incidence decreased by 22% and the proportion of multidrug-resistant isolates decreased by 80% during 2012–2016.
Kristina Rizzardi, Torbjörn Norén, Olov Aspevall, Barbro Mäkitalo, Michael Toepfer, Åsa Johansson, Thomas Åkerlund   +6 more
doaj   +1 more source