Results 91 to 100 of about 168,874 (243)

Imaging of Abdominal Complications in Children With Acute Lymphoblastic Leukaemia

Journal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Acute lymphoblastic leukaemia (ALL) is the most common paediatric malignancy and remains one of the most common causes of cancer‐related death in children and adolescents. Five‐year overall survival rates now exceed 90% with current multidrug chemotherapeutic regimens. This improvement, coupled with the toxicity of chemotherapy, has led to the
Luke R. Holmes, Rishi S. Kotecha, Derek J. Roebuck   +2 more
wiley   +1 more source

Incidence of hospital-acquired toxin-producing clostridioides difficile infection between the pre-pandemic (2017–2019) and pandemic (2020–2022): a retrospective cohort study

Archives of Public Health
Background In 2020, the World Health Organization declared SARS-CoV-2 a global public health emergency. Healthcare systems were forced to reorganize care delivery and implement wide-ranging infection control strategies. Among hospital-acquired infections,
Raquel García Rodríguez, María José Pereira Rodríguez, Alejandra Pilar García López, Fabián Freijedo Fariñas, Angela Nogueira Gómez   +4 more
doaj   +1 more source

Quantification of Clostridioides (Clostridium) difficile in feces of calves of different age and determination of predominant Clostridioides difficile ribotype 033 relatedness and transmission between family dairy farms using multilocus variable-number tandem-repeat analysis

BMC Veterinary Research, 2018
Background Community acquired Clostridioides (Clostridium) difficile infection (CA-CDI) is a significant health problem in human and veterinary medicine. Animals are often considered as potential reservoirs for CA-CDI.
Petra Bandelj, Céline Harmanus, Rok Blagus, Marko Cotman, Ed J. Kuijper, Matjaz Ocepek, Modest Vengust   +6 more
doaj   +1 more source

Clostridioides difficile pathogenesis and control

Nature Reviews Microbiology
Clostridioides difficile infection (CDI) continues to be a notable burden worldwide, both in terms of patient mortality and morbidity, and the economic costs associated with treatment, diagnosis and management. The epidemiology of C. difficile has changed markedly over the decades, with high CDI rates driven by clinical pressures exacerbated by the ...
Chilton, C.H., Viprey, V., Normington, C., Moura, I.B., Buckley, A.M., Freeman, J., Davies, K., Wilcox, M.H.   +7 more
openaire   +3 more sources

Clostridioides difficile (formerly known as Clostridium difficile) [PDF]

Clostridioides difficile (also known as C. diff ) is a bacterium that causes diarrhea and colitis (an inflammation of the colon). C. diff infection can be life-threatening.CS316107-APublication date from document properties.Cdiff-Factsheet-P ...

core  

Review Article: Immune Effector Cell‐Mediated Enterocolitis Following CAR‐T Cell Therapy—Clinical Features, Pathophysiology and Management

Alimentary Pharmacology &Therapeutics, EarlyView.
Immune effector cell‐mediated enterocolitis is an emerging complication of CAR‐T therapy. This review summarizes its epidemiology, pathophysiology, diagnosis, endoscopic and histopathologic features, and evidence‐based management, emphasizing early recognition, multidisciplinary intervention, and step‐up therapy.
John A. Damianos, Yi Lin, Zongming Eric Chen, Kenneth J. C. Lim, Navreet M. Chowla   +4 more
wiley   +1 more source

Gut microbiota as a novel therapeutic target for eating disorders and obesity

British Journal of Pharmacology, EarlyView.
The graphical abstract highlights the bidirectional interaction between the gut microbiota and central homeostatic and hedonic mechanisms regulating food intake, which contributes to overweight and obesity. It also illustrates emerging microbiota‐based biomarkers and therapeutic strategies (including prebiotics, probiotics, postbiotics, synbiotics and ...
Solveiga Samulėnaitė, Victor Mathis, Emmanuel Darcq, Aurelijus Burokas, Elena Martín‐García, Rafael Maldonado   +5 more
wiley   +1 more source

Lactoferrin-Loaded Alginate Microparticles to Target Clostridioides difficile Infection [PDF]

, 2019
Some forms of bovine lactoferrin (bLf) are effective in delaying Clostridioides difficile growth and preventing toxin production. However, therapeutic use of bLf may be limited by protein stability issues.
Śpiewak, Klaudyna, Brindell, Małgorzata, Heeg, Daniela, Alexander, Cameron, Braim, Shwana, Monaghan, Tanya, Śpiewakb, Klaudyna, Brindell, Malgorzata   +7 more
core   +1 more source

A publicly accessible database for Clostridioides difficile genome sequences supports tracing of transmission chains and epidemics [PDF]

, 2020
Clostridioides difficile is the primary infectious cause of antibiotic-associated diarrhea. Local transmissions and international outbreaks of this pathogen have been previously elucidated by bacterial whole-genome sequencing, but comparative genomic ...
Blaschitz, Marion, von Müller, Lutz, García-Fernández, Sergio, Indra, Alexander, Meier-Kolthoff, Jan P., Lawley, Trevor D, Steglich, Matthias, Seyboldt, Christian, del Campo, Rosa, Kohl, Thomas A, Kumar, Nitin, Lawley, Trevor D., Lawley, Trevor, Meier-Kolthoff, Jan P, Frentrup, Martinique, Kohl, Thomas A., Göker, Markus, Zimmermann, Ortrud, Achtman, Mark, Bunk, Boyke, Groß, Uwe, Spröer, Cathrin, Zhou, Zhemin, Cantón, Rafael, Niemann, Stefan, Meier-Kolthoff, Jan, Riedel, Thomas, Klawonn, Frank, Nübel, Ulrich, Overmann, Jörg   +29 more
core   +1 more source

Tigecycline combination therapy for fulminant Clostridioides difficile infection: an Australian experience

Internal Medicine Journal, EarlyView.
Abstract Background Recent European Society of Clinical Microbiology and Infection and Australasian Society of Infectious Diseases Clostridioides difficile infection (CDI) management guidelines endorse the addition of intravenous tigecycline in patients who are progressing to fulminant infection.
Emma Bishop, Tanya Ravipati, Steven Mileto, Eugene Athan, Dena Lyras, Ravindranath Tiruvoipati   +5 more
wiley   +1 more source