Results 111 to 120 of about 171,697 (237)

Antimicrobial resistance surveillance of Clostridioides difficile in Australia, 2015-18

, 2021
Background Clostridioides difficile was listed as an urgent antimicrobial resistance (AMR) threat in a report by the CDC in 2019. AMR drives the evolution of C. difficile and facilitates its emergence and spread. The C.
Hemphill, Christine, Lahra, Monica, Putsathit, Papanin, George, Narelle, Prendergast, Louise, Hong, Stacey, Korman, Tony M., McGlinchey, Andrew, McDougall, Rodney, Weldhagen, Gerhard F., Robson, Jennifer, Knight, Daniel R., Moore, Casey V., Waring, Lynette, Wilson, Richard M., Kotsanas, Despina, Riley, Thomas V., Huntington, Peter G., Wehrhahn, Michael C., Nimmo, Graeme R., Kotsanas, D, McDougall, R, Robson, J, Hong, S, Nimmo, GR, Hemphill, C, Putsathit, P, McGlinchey, A, Moore, CV, Huntington, PG, Lahra, M, George, N, Prendergast, L, et al., Korman, TM, Christine Hemphill, Jennifer Robson, Narelle George, Monica Lahra, Daniel R Knight, Despina Kotsanas, Papanin Putsathit, Casey V Moore, Michael C Wehrhahn, Andrew McGlinchey, Tony M Korman, Graeme R Nimmo, Gerhard F Weldhagen, Rodney McDougall, Louise Prendergast, Peter G Huntington, Thomas V Riley, Lynette Waring, Stacey Hong, Richard M Wilson   +54 more
core   +1 more source

Whole genome sequence analysis reveals limited diversity among Clostridioides difficile ribotype 027 and 078 isolates collected in 22 hospitals in Berlin and Brandenburg, Germany

Antimicrobial Resistance and Infection Control
Background Clostridioides difficile infections (CDI) present significant health risks and are among the most important nosocomial infections. Ribotype (RT) 027 poses a particular risk due to its proposed “hypervirulence”. Traditionally, C.
Esther E. Dirks, Vanessa Pfiffer, Genevieve Sohl, Fabian K. Berger, Ina Friesen, Johannes Friesen, Ralf Ignatius, Johannes Elias, Alexander Mellmann, Mardjan Arvand   +9 more
doaj   +1 more source

Medication Use and Risk of Microscopic Colitis: A Propensity‐Matched Analysis of US Adults ≥ 50 Years (2014–2024)

Alimentary Pharmacology &Therapeutics, EarlyView.
Commonly prescribed NSAIDs, PPIs and SSRIs were associated with a higher risk of microscopic colitis after propensity score matching, whereas ACE inhibitors, ARBs and statins showed no significant association. ABSTRACT Background The association between medications—including non‐steroidal anti‐inflammatory drugs (NSAIDs), proton pump inhibitors (PPIs ...
Yassine Kilani, Farah Heis, Andrew Dugaesescu, Youssef Hafez, Shadi Hamdeh, Wissam Kiwan, Mahmoud Y. Madi   +6 more
wiley   +1 more source

Gut microbiota as a novel therapeutic target for eating disorders and obesity

British Journal of Pharmacology, EarlyView.
The graphical abstract highlights the bidirectional interaction between the gut microbiota and central homeostatic and hedonic mechanisms regulating food intake, which contributes to overweight and obesity. It also illustrates emerging microbiota‐based biomarkers and therapeutic strategies (including prebiotics, probiotics, postbiotics, synbiotics and ...
Solveiga Samulėnaitė, Victor Mathis, Emmanuel Darcq, Aurelijus Burokas, Elena Martín‐García, Rafael Maldonado   +5 more
wiley   +1 more source

Clostridioides Difficile Infection

Diseases of the Colon & Rectum, 2020
Linda, Ferrari, Alessandro, Fichera
openaire   +5 more sources

Trends and regional variation in antibiotic prescribing by dentists in Finland, 2012–2025: A register‐based study

European Journal of Oral Sciences, EarlyView.
Abstract This nationwide register‐based study aimed to investigate trends and regional variation in the number of antibiotic prescriptions issued by dentists in Finland from 2012 to 2025. Data on reimbursed outpatient antibiotic prescriptions dispensed by Finnish pharmacies were used.
Terhi Laitala, Emma Aarnio, Katariina Tuomilinna, Eero Raittio, Jukka Leinonen   +4 more
wiley   +1 more source

Contribution of MALDI‐TOF mass spectrometry and machine learning including deep learning techniques for the detection of virulence factors of Clostridioides difficile strains

Microbial Biotechnology
Clostridioides difficile (CD) infections are defined by toxins A (TcdA) and B (TcdB) along with the binary toxin (CDT). The emergence of the ‘hypervirulent’ (Hv) strain PR 027, along with PR 176 and 181, two decades ago, reshaped CD infection ...
Alexandre Godmer, Quentin Giai Gianetto, Killian Le Neindre, Valentine Latapy, Mathilda Bastide, Muriel Ehmig, Valérie Lalande, Nicolas Veziris, Alexandra Aubry, Frédéric Barbut, Catherine Eckert   +10 more
doaj   +1 more source

Tigecycline combination therapy for fulminant Clostridioides difficile infection: an Australian experience

Internal Medicine Journal, EarlyView.
Abstract Background Recent European Society of Clinical Microbiology and Infection and Australasian Society of Infectious Diseases Clostridioides difficile infection (CDI) management guidelines endorse the addition of intravenous tigecycline in patients who are progressing to fulminant infection.
Emma Bishop, Tanya Ravipati, Steven Mileto, Eugene Athan, Dena Lyras, Ravindranath Tiruvoipati   +5 more
wiley   +1 more source

Mechanisms of Clostridioides difficile glucosyltransferase toxins and their roles in pathology: insights and emerging therapeutic strategies

Frontiers in Cellular and Infection Microbiology
Clostridioides difficile infection (CDI) is a significant cause of antibiotic-associated diarrhea and pseudomembranous colitis, manifesting as mild diarrhea, fulminant colitis, and even death.
Xin Wen, Xue Liu, Kai Wan, Hong Liu, Cheng Zhang, Xi Zhang, Qin Wen   +6 more
doaj   +1 more source

Epidemiological characteristics of infections caused by bacteria Clostridioides difficile toxins [PDF]

Srpski Arhiv za Celokupno Lekarstvo
Introduction/Objective. Clostridioides difficile is one of the most common infectious agents and an important cause of infections among hospitalized patients, often resulting in severe and potentially fatal outcomes.
Koprivica Marko, Đekić-Malbaša Jelena
doaj   +1 more source