Results 131 to 140 of about 143,361 (253)

Metagenomic, metabolomic, and lipidomic shifts associated with fecal microbiota transplantation for recurrent Clostridioides difficile infection

Msphere
Recurrent C. difficile infection (rCDI) is an urgent public health threat, for which the last resort and lifesaving treatment is a fecal microbiota transplant (FMT).
Arthur S. McMillan, Guozhi Zhang, Michael K. Dougherty, Sarah K. McGill, A. S. Gulati, E. Baker, C. Theriot   +6 more
semanticscholar   +1 more source

Structural and functional insight into the interaction of Clostridioides difficile toxin B and FZD7

Cell Reports
Summary: The G protein-coupled receptors of the Frizzled (FZD) family, in particular FZD1,2,7, are receptors that are exploited by Clostridioides difficile toxin B (TcdB), the major virulence factor responsible for pathogenesis associated with ...
Julia Kinsolving, Julien Bous, Pawel Kozielewicz, Sara Košenina, Rawan Shekhani, Lukas Grätz, Geoffrey Masuyer, Yuankai Wang, Pål Stenmark, Min Dong, Gunnar Schulte   +10 more
doaj   +1 more source

COVID-19 and Clostridioides difficile Coinfection Analysis in the Intensive Care Unit

Antibiotics
Since the emergence of SARS-CoV-2 in late 2019, the global mortality attributable to COVID-19 has reached 6,972,152 deaths according to the World Health Organization (WHO).
M. Stoian, Adina Andone, A. Boeriu, S. Bândilă, D. Dobru, S. Laszlo, Dragoș Corău, Emil-Marian Arbănași, Eliza Russu, A. Stoian   +9 more
semanticscholar   +1 more source

MEAT PIES: Mammalian Meat Allergy in Patients Investigated for Gastrointestinal Symptoms

JGH Open, Volume 10, Issue 6, June 2026.
ABSTRACT Background Alpha‐gal syndrome (AGS), an IgE‐mediated allergy to galactose‐α‐1,3‐galactose acquired via tick bites, often presents with a delayed gastrointestinal (GI) phenotype without anaphylaxis. We evaluated a local diagnostic guideline in a Far North Queensland gastroenterology outpatient clinic.
Elias Bitzer, Peter Bourke, Shihaz Hussain   +2 more
wiley   +1 more source

INHIBITORII POMPEI DE PROTONI ȘI RISCUL INFECȚIEI CU CLOSTRIDIOIDES DIFFICILE

Buletinul Academiei de Ştiinţe a Moldovei: Ştiinţe Medicale
Infecția cu Clostridioides difficile a fost evidențiată ca o problemă majoră de sănătate publică, inclusiv ca una din cele mai frecvente infecții asociate asistenței medicale.
Nicolae BACINSCHI , Ina GUȚU, Alexandru IAROVOI, Maria MIHALACHI-ANGHEL, Tatiana RAKOVSKAIA   +4 more
doaj   +1 more source

Gut Microbiota as a Key Modulator in the Pathophysiology of Sepsis: SURVEIL Project

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
Longitudinal profiling of 132 hospitalized patients reveals that age, colonization status, and sepsis interact to shape gut microbiota diversity and composition. Sepsis is associated with reduced alpha diversity, beta‐diversity shifts, functional predictions (methanogenesis, nitrate/sulfate respiration), and partial MDR overlap with bloodstream ...
Chiara Bazzano, Alice Caramaschi, Nadia Massa, Silvio Collani, Marta Mellai, Nadia Barizzone, Andrea Rocchetti, Paolo Bottino, Maria Simona Caroppo, Valeria Bonato, Rosanna Vaschetto, Sara Scaglione, Alessia Francese, Narges Gholami, Claudio Caria, Paola Bianchi, Cristiano Lauritano, Luigi Castello, Annalisa Roveta, Antonio Maconi, Stefano Andreoni, Sandra Dalfonso, Elisa Bona   +22 more
wiley   +1 more source

A Real-World Study on the Clinical Characteristics, Outcomes, and Relationship between Antibiotic Exposure and Clostridioides difficile Infection

Antibiotics
Clostridioides difficile is a Gram-positive bacteria that causes nosocomial infections, significantly impacting public health. In the present study, we aimed to describe the clinical characteristics, outcomes, and relationship between antibiotic exposure
B. Vintilă, A. Arseniu, C. Morgovan, Anca Butuca, V. Bîrluțiu, C. Dobrea, L. Rus, S. Ghibu, A. Bereanu, Rares Arseniu, Ioana Roxana Codru, Mihai Sava, Felicia Gabriela Gligor   +12 more
semanticscholar   +1 more source

Production of Multiple Variants of the Antimicrobial Sactipeptide Gnavucin D by the Human Gut Isolate Mediterraneibacter gnavus HB038

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
Gnavucin D, a novel antibacterial sactipeptide produced by Mediterraneibacter gnavus HB038, exhibits activity against multiple pathogens, including Clostridium perfringens, Streptococcus agalactiae, Bacillus cereus, and vancomycin‐resistant Enterococcus.
Mengfan Ding, Felipe Miceli de Farias, Paula M. O'Connor, Xiaohui Huang, Fiona C. Ross, Elaine C. Kennedy, Colin P. Hawkes, Colin Hill, Catherine Stanton, Reynolds Paul Ross   +9 more
wiley   +1 more source

Divergent Resilience of Bacterial and Fungal Gut Microbiota After Colorectal Surgery: Insights From a Prospective Longitudinal Cohort Study

MedComm, Volume 7, Issue 6, June 2026.
Patients undergoing colorectal surgery (n = 59) were sampled before and after surgery to investigate perioperative microbiome dynamics. Using 16S rRNA and ITS2 genes amplicon sequencing, bacterial diversity significantly decreased postoperatively, while fungal communities remained resilient.
Simon Wetzel, Eva Kohnert, Roman Huber, Alexander Müller, Agnes Knott, Lampros Kousoulas, Clemens Kreutz, Mohamed Tarek Badr, Ann‐Kathrin Lederer   +8 more
wiley   +1 more source

The Expanding Landscape of Microbiota Medicine: Indications, Therapeutic Modalities, and the Path Towards Integrative Microbiome‐Targeting Healthcare

Microbiota Medicine Research, Volume 1, Issue 2, Page 63-89, June 2026.
ABSTRACT The growing recognition of the microbiome’s role in human health has propelled the emergence of microbiota medicine—a new discipline integrating microbiology, multi‐omics, and clinical science. Advances in sequencing, data integration, and interventions such as fecal microbiota transplantation (FMT) have transitioned the field from ...
Min Dai, Yisha Lin, Renyou Gan, Xiaotao Shen, Shin Young Park, Sunjae Lee, Qi Su   +6 more
wiley   +1 more source