Results 121 to 130 of about 168,874 (243)
International Journal of Dermatology, Volume 65, Issue 10, Page 2001-2004, October 2026.ABSTRACT Interest in the gut microbiome as a therapeutic target for treating alopecia areata (AA) has grown considerably. However, existing evidence remains limited and inconsistent. Currently, there is insufficient evidence to recommend microbiome‐directed testing and therapies to patients with AA.
Eric McMullen +9 more
wiley +1 more source
Characterization of High-Linezolid-MIC Clostridioides difficile Isolated from a Chinese Hospital: First Genomic Evidence of Cfr(B) Transmission and Tn6218 Association [PDF]
Xuyan Fu,1,* Xiajing Bi,2,* Tao Lv,1 Yunbo Chen1 1State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and ...
Bi X, Fu X, Lv T, Chen Y
core
The current riboswitch landscape in Clostridioides difficile
International audienceRiboswitches are 5′ RNA regulatory elements that are capable of binding to various ligands, such as small metabolites, ions and tRNAs, leading to conformational changes and affecting gene transcription or translation.
Soutourina, Olga +2 more
core +1 more source
Veterinary Dermatology, Volume 37, Issue 5, Page 735-744, October 2026.Background: Faecal microbiota transplantation (FMT) is an established therapy for gastrointestinal disease, yet its role in canine atopic dermatitis (cAD) remains unclear. Hypothesis/Objectives: We hypothesised that adjunctive FMT improves clinical severity and reduces symptomatic medication use in dogs with cAD.
Vera Felten +9 more
wiley +1 more source
The FASEB Journal, Volume 40, Issue 17, 15 September 2026.Dietary components shape the gut microbiome, which modifies bile acids through transformations. The resulting bile acid pool is sensed by host receptors to regulate immunity, metabolism, and intestinal function. Targeted bile acid measurements provide a unifying readout to study diet‐microbiome interactions and to develop next‐generation dietary ...
Jason Dichter
wiley +1 more source
Synthesis of Glycopeptide Antibiotic Peptide Substrates Using Knorr‐Pyrazole Chemistry
ChemMedChem, Volume 21, Issue 17, 14 September 2026.The glycopeptide antibiotics (GPAs) are important clinical antibiotics. While chemoenzymatic synthesis of more hydrophilic GPAs like vancomycin has aided our understanding of GPA crosslinking, hydrophobic GPAs remain underexplored. Here, we show that modified Knorr‐pyrazole chemistry improves access to hydrophobic peptidyl‐CoAs, with such substrates ...
Jemma Gullick +4 more
wiley +1 more source
Background.Antimicrobial susceptibility testing (AST) is not routinely performed for Clostridioides difficile and data evaluating minimum inhibitory concentrations (MICs) are limited.
core +2 more sources
Pediatric Blood &Cancer, Volume 73, Issue 9, September 2026.ABSTRACT Pediatric supportive care clinical trials often involve multiple clinically important outcomes, complicating trial interpretation. Hierarchical composite endpoints (HCEs) provide a framework to integrate key outcomes according to clinical importance.
Willem H. Collier +11 more
wiley +1 more source
Clinical Case Reports, Volume 14, Issue 9, September 2026.ABSTRACT Antimalarial cardiotoxicity may mimic lupus myocarditis in systemic lupus erythematosus. We report a 53‐year‐old woman with chronic antimalarial exposure, myocardial injury, biventricular dysfunction, electrical abnormalities, low lupus activity, and no myocardial edema.
Diego Armando Pérez Covo +9 more
wiley +1 more source
Clostridioides difficile in chicken fresh meat at retail in France
International audienceFoodborne transmission of Clostridioides difficile is strongly suspected, particularly through poultry fresh meat products. In this study, C. difficile was detected in 1.5% of chicken thighs (n = 271) but in none of the cutlets (n =
Reboul, Guillaume +7 more
core +1 more source