BMC Infectious DiseasesBackground Recurrent Clostridioides difficile infection is most effectively treated with faecal microbiota transplantation. Swedish and European guidelines suggest faecal microbiota transplantation after a first or second recurrence, respectively.
Måns Stefansson +5 more
doaj +1 more source
\u3ci\u3eClostridioides difficile\u3c/i\u3e Infection Study Models and Prospectives for Probing the Microbe-Host Interface [PDF]
Clostridioides difficile infection (CDI) is an urgent public health threat with a high rate of recurrence and limited treatment options. In vivo models have been indispensable in understanding CDI pathophysiology and establishing treatment protocols and ...
Courson, David S. +2 more
core +1 more source
A Review of Therapies for Clostridioides difficile Infection
AntibioticsClostridioides difficile is an urgent public health threat that affects approximately half a million patients annually in the United States. Despite concerted efforts aimed at the prevention of Clostridioides difficile infection (CDI), it remains a ...
Faiza Morado, Neha Nanda
doaj +1 more source
Real-world Effectiveness of Fecal Microbiota Transplantation for First or Second Clostridioides difficile Infection [PDF]
Background & Aims: Clostridioides difficile infection (CDI) is associated with high mortality. Fecal microbiota transplantation (FMT) is an established treatment for recurrent CDI, but its use for first or second CDI remains experimental. We aimed to
Baumwall, Simon Mark Dahl +20 more
core +2 more sources
Evaluation of cases of Clostridioides difficile detected in a tertiary hospital in western Paraná state, Brazil. [PDF]
Background: Clostridioides difficile is an obligate anaerobic, gram-positive bacillus, with subterminal spores. It is also a producer of enterotoxins. Prolonged use of broad-spectrum antimicrobials in immunocompromised patients is often related to the ...
Ayres Torres Takaes, Rodrigo +4 more
core +1 more source
Clostridioides difficile infection: an update
Infezioni in MedicinaClostridioides difficile (C. difficile) is a Gram-positive, spore-forming anaerobic bacterium emerged as a leading cause of diarrhea globally. CDI's (Clostridioides difficile infection) impact on healthcare systems is concerning due to high treatment cost and increased hospitalisation time.
Federica, Salvati +4 more
openaire +2 more sources
Clostridioides difficile (C. difficile) [PDF]
Type: BacteriaAlso known as: C. difficile or C. diff, previously Clostridium difficileAbout: C. difficile causes life-threatening diarrhea and colitis (an inflammation of the colon), mostly in people who have had both recent medical care and antibiotics ...
core
Microbiota Restoration Therapies for Recurrent Clostridioides difficile Infection Reach an Important New Milestone [PDF]
Microbiota restoration therapy has become a standard treatment for recurrent Clostridioides difficile infection (rCDI). In this article, we review the studies supporting the licensure of two live biotherapeutic products (LBPs) designed to prevent rCDI ...
DuPont, Andrew W +2 more
core +1 more source
Comparison of Patient Outcomes in a Pharmacist-Led Parenteral Antimicrobial Therapy Program [PDF]
, 2020 Howe, Zachary W. +2 more
core +1 more source
SHEA neonatal intensive care unit (NICU) white paper series: Practical approaches to Clostridioides difficile prevention [PDF]
, 2018 Bartlett, Allison H +5 more
core +1 more source