Results 131 to 140 of about 34,117 (261)

Consortium of Probiotics Attenuates Colonization of Clostridioides difficile

Frontiers in Microbiology, 2019
Clostridioides difficile infection (CDI) is increasing morbidity and mortality rates globally. Fecal microbiota transplantation (FMT), an effective therapy for eliminating Clostridioides difficile (C.
Xianping Li, Xianping Li, Qiongfang Chu, Qiongfang Chu, Qiongfang Chu, Yuanming Huang, Yuanming Huang, Yuchun Xiao, Yuchun Xiao, Liqiong Song, Liqiong Song, Siyi Zhu, Siyi Zhu, Ying Kang, Ying Kang, Shan Lu, Shan Lu, Jianguo Xu, Jianguo Xu, Zhihong Ren, Zhihong Ren   +20 more
doaj   +1 more source

Multiple factors contribute to bimodal toxin gene expression in Clostridioides (Clostridium) difficile [PDF]

, 2018
Eric M. Ransom, Gabriela M. Kaus, Phuong M. Tran, Craig D. Ellermeier, David S. Weiss   +4 more
openalex   +1 more source

Structural and functional insight into the interaction of Clostridioides difficile toxin B and FZD7

Cell Reports
Summary: The G protein-coupled receptors of the Frizzled (FZD) family, in particular FZD1,2,7, are receptors that are exploited by Clostridioides difficile toxin B (TcdB), the major virulence factor responsible for pathogenesis associated with ...
Julia Kinsolving, Julien Bous, Pawel Kozielewicz, Sara Košenina, Rawan Shekhani, Lukas Grätz, Geoffrey Masuyer, Yuankai Wang, Pål Stenmark, Min Dong, Gunnar Schulte   +10 more
doaj   +1 more source

Effective fecal microbiota transplantation for recurrent Clostridioides difficile infection in humans is associated with increased signalling in the bile acid-farnesoid X receptor-fibroblast growth factor pathway [PDF]

, 2018
Tanya Monaghan, Benjamin H. Mullish, Jordan Patterson, Gane Ka‐Shu Wong, Julian R. Marchesi, Huiping Xu, Tahseen Jilani, Dina Kao   +7 more
openalex   +1 more source

Deletion of Prophages in Clostridioides difficile

, 2022
Clostridioides difficile (C. difficile) formally known as Clostridium difficile, is a Gram-positive spore forming anaerobe responsible for almost all cases of pseudomembranous colitis and is implicated in 25-33% of antibiotic associated diarrhoea. Many C.
openaire   +2 more sources

Difference in Mono-O-Glucosylation of Ras Subtype GTPases Between Toxin A and Toxin B From Clostridioides difficile Strain 10463 and Lethal Toxin From Clostridium sordellii Strain 6018 [PDF]

, 2018
Harald Genth, Johannes Junemann, Chantal M. Lämmerhirt, Arlen-Celina Lücke, Ilona Schelle, Ingo Just, Ralf Gerhard, Andreas Pich   +7 more
openalex   +1 more source

Clostridioides difficile infection: an update

Infezioni in Medicina
Clostridioides difficile (C. difficile) is a Gram-positive, spore-forming anaerobic bacterium emerged as a leading cause of diarrhea globally. CDI's (Clostridioides difficile infection) impact on healthcare systems is concerning due to high treatment cost and increased hospitalisation time.
Federica, Salvati, Francesca, Catania, Rita, Murri, Massimo, Fantoni, Carlo, Torti   +4 more
openaire   +2 more sources

Curbing inappropriate C. difficile treatment in patients receiving concomitant laxatives

Antimicrobial Stewardship & Healthcare Epidemiology
In the setting of universal Clostridioides difficile screening, we implemented an alert that triggered when C. difficile treatment was ordered in patients who recently received laxatives. This resulted in C.
Paige Fields, Christopher David, Anish Choksi, Natasha N. Pettit, Alison K. Lew, Jennifer Pisano, Cynthia T. Nguyen   +6 more
doaj   +1 more source

Real-world Effectiveness of Fecal Microbiota Transplantation for First or Second Clostridioides difficile Infection [PDF]

Background & Aims: Clostridioides difficile infection (CDI) is associated with high mortality. Fecal microbiota transplantation (FMT) is an established treatment for recurrent CDI, but its use for first or second CDI remains experimental. We aimed to
Baumwall, Simon Mark Dahl, Birn, Frederik Hyllested, Dahlerup, Jens Frederik, Erikstrup, Christian, Erikstrup, Lise Tornvig, Fernis, Christa Marie Culmbach, Glerup, Henning, Grosen, Anne Karmisholt, Hansen, Mette Mejlby, Helms, Morten, Hvas, Christian Lodberg, Kelsen, Jens, Krarup, Anne Lund, Lødrup, Anders Bergh, Mikkelsen, Susan, Neumann, Anders, Paaske, Sara Ellegaard, Rubak, Tone, Rågård, Nina, Svenningsen, Lise, Vinter-Jensen, Lars   +20 more
core   +1 more source

Bacteriophages Contribute to Shaping Clostridioides (Clostridium) difficile Species [PDF]

, 2018
Louis‐Charles Fortier
openalex   +1 more source