Results 131 to 140 of about 31,421 (293)

Prospective Review of Clostridioides difficile Testing Indications to Inform Local Laboratory Stewardship Initiatives

open access: yesInfection Prevention in Practice, 2019
Summary: We conducted a prospective chart review to determine the prevalence of and reasons for inappropriate Clostridioides difficile test-ordering at a tertiary care hospital. Inappropriate orders accounted for 54% of all tests.
Noah Reich   +7 more
doaj  

Antimicrobial resistance and use, and rates of hospitalization associated with bacterial infections, including sepsis [PDF]

open access: yesarXiv, 2018
While the mechanisms and quantitative details are complex, few analysts would doubt that antibiotic use increases the prevalence of drug-resistant bacterial pathogens among all bacteria causing disease in a population. The causal connection between antibiotic use and the total incidence of severe bacterial infections, possibly mediated by antibiotic ...
arxiv  

Use of Human In Vitro Gut Specimens for Translational Neurogastroenterology and Motility in the 21st Century

open access: yesNeurogastroenterology &Motility, EarlyView.
In vitro studies with GI surgical specimens or biopsy are a critical step in translating preclinical studies in animals to humans before testing potential therapeutic interventions in expensive clinical trials. Routine availability of human gut specimens, in combination with technological advances and powerful new in vitro models of the human ENS from ...
Dmitrii Pavlov, Fievos L. Christofi
wiley   +1 more source

Consortium of Probiotics Attenuates Colonization of Clostridioides difficile

open access: yesFrontiers in Microbiology, 2019
Clostridioides difficile infection (CDI) is increasing morbidity and mortality rates globally. Fecal microbiota transplantation (FMT), an effective therapy for eliminating Clostridioides difficile (C.
Xianping Li   +20 more
doaj   +1 more source

The cytotoxic synergy between Clostridioides difficile toxin B and proinflammatory cytokines: an unholy alliance favoring the onset of Clostridioides difficile infection and relapses

open access: yesMicrobiologyOpen, 2020
Clostridioides difficile infection (CDI) represents an important health problem worldwide, with significant morbidity and mortality. This infection has also high recurrence rates, whose pathophysiological grounds are still poorly understood. Based on our
Gabrio Bassotti   +3 more
doaj   +1 more source

Photodynamic therapy of cancer‐associated infections

open access: yesPhotochemistry and Photobiology, EarlyView.
Pathogens can be involved in tumor initiation, promotion and progression through different mechanisms, and their treatment can prevent new cancer cases, improve outcomes, and revert poor‐prognostic phenotypes. Photodynamic therapy (PDT) successfully treats different types of cancers and infections, and, therefore, has a unique potential to address ...
Giulia Kassab, Juan Chen, Gang Zheng
wiley   +1 more source

The Epidemiology of Clostridioides Difficile in Nebraska - A Descriptive Study Between 2018-2020 [PDF]

open access: yes, 2021
Objectives: Clostridioides difficile (C. diff) is a common but challenging infection both financially and medically. Due to these difficulties, Clostridioides difficile infection (CDI) caused by C.
Keffer, Storm
core   +1 more source

Repurposing auranofin as a Clostridioides difficile therapeutic

open access: yesJournal of Antimicrobial Chemotherapy, 2019
Abstract Background Clostridioides difficile (previously Clostridium difficile) is the leading cause of nosocomial, antibiotic-associated diarrhoea worldwide. Currently, the gold standard of treatment for C.
Havva Pehlivanoglu   +5 more
openaire   +3 more sources

Antibiotic Exposure and Risk of Allograft Rejection and Survival After Liver Transplant: An Observational Cohort Study From a Tertiary Referral Centre

open access: yesTransplant Infectious Disease, EarlyView.
Because the relationship between the gut microbiota and liver transplant outcomes is not well described, it is possible that there are, as yet, unrecognized negative impacts of antibiotic exposures on key liver transplant‐related outcomes. We observed a negative association between antibiotic exposures, particularly those with an anaerobic spectrum of ...
Olivia C. Smibert   +11 more
wiley   +1 more source

Theorie De Galois Des Equations Differentielles [PDF]

open access: yesarXiv, 2003
Let k be a differential field and C its subfield of constants. In general a differential extension K of k add some new constants to C, and it is difficult to prove that C stay unchangeable under the extension K; This situation is provided by the Picard-Vessiot extension. Kolchin prove the theorem of existence and unicity for these extensions.
arxiv  

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