Results 11 to 20 of about 168,874 (243)
Extraintestinal Clostridioides difficile infection
Clostridioides (Clostridium) difficile is the major cause of healthcare antibiotic-associated diarrhoea. However, extra-intestinal manifestations of Clostridioides (Clostridium) difficile infection (CDI) (including bacteremia and tissue infection) are ...
Zhao Hai +6 more
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Clostridioides difficile infection is the most common cause of antibiotic-associated diarrhea. IDSA/SHEA, ESCMID and ACG updated the clinical practice guidelines for CDI in 2021. This paper is an attempt to summarize these guidelines.
Mateusz Piotr Baran +4 more
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Clostridioides difficile Biofilm
Clostridioides difficile infection (CDI), previously Clostridium difficile infection, is a symptomatic infection of the large intestine caused by the spore-forming anaerobic, gram-positive bacterium Clostridioides difficile. CDI is an important healthcare-associated disease worldwide, characterized by high levels of recurrence, morbidity, and mortality.
Vuotto, C. +3 more
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Clostridioides difficile Colitis
Clostridioides difficile colitis is an important source of hospital-acquired diarrhea associated with antibiotic use. Symptoms are profuse watery diarrhea, typically following a course of antibiotics; however, some cases of fulminant disease may manifest with shock, ileus, or megacolon. Nonfulminant colitis is treated with oral fidaxomicin. C difficile
Luke, Pumiglia +2 more
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Clostridioides difficile Infection [PDF]
This book collects multidisciplinary research articles focused on Clostridioides difficile infection. The contributions collected here shed some light on grey areas of our knowledge of Clostridioides difficile, including regional Clostridioides difficile
core +1 more source
Clostridioides difficile is a Gram positive spore-forming rod and mainly responsible for nosocomial diarrhea in developed nations. Molecular and antimicrobial surveillance is important for monitoring the strain composition including genotypes of high ...
Ahmed Mohamed Mostafa Abdrabou +9 more
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The immunological response against Clostridioides difficile (C. difficile) is crucial for an improved understanding of disease mechanisms and the development of novel therapeutic strategies.
Sophie Roth +10 more
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Plasmids of Clostridioides difficile
Plasmids are ubiquitous in the bacterial world. In many microorganisms, plasmids have been implicated in important aspects of bacterial physiology and contribute to horizontal gene transfer. In contrast, knowledge on plasmids of the enteropathogen Clostridioides difficile is limited, and there appears to be no phenotypic consequence to carriage of many
Smits, W.K., Roseboom, A.M., Corver, J.
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Recently, the recommendations for the treatment of Clostridioides difficile infection (CDI) have been updated. However, in addition to the clinical efficacy data, the drug of choice should ideally represent optimal antimicrobial stewardship, with an ...
Marcela Krutova, Mark Wilcox, Ed Kuijper
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Clostridioides difficile [PDF]
Clostridioides difficile is a spore-forming, anaerobic, intestinal pathogen that causes severe diarrhea that can lead to death. In 2011, C. difficile infected ∼500000 people in the USA and killed ∼29000 people. C. difficile infection (CDI) is the most common healthcare-related infection in the USA, leading to increased healthcare costs of $4.8 billion.
Brindar K, Sandhu, Shonna M, McBride
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