Extraintestinal Clostridioides difficile infection
IDCases, 2020 Clostridioides (Clostridium) difficile is the major cause of healthcare antibiotic-associated diarrhoea. However, extra-intestinal manifestations of Clostridioides (Clostridium) difficile infection (CDI) (including bacteremia and tissue infection) are ...
Zhao Hai +6 more
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Clostridioides difficile [PDF]
Trends in Microbiology, 2018 Clostridioides difficile is a spore-forming, anaerobic, intestinal pathogen that causes severe diarrhea that can lead to death. In 2011, C. difficile infected ∼500000 people in the USA and killed ∼29000 people. C. difficile infection (CDI) is the most common healthcare-related infection in the USA, leading to increased healthcare costs of $4.8 billion.
Brindar K, Sandhu, Shonna M, McBride
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Evaluating the capacity of human gut microorganisms to colonize the zebrafish larvae (Danio rerio) [PDF]
, 2018 Indexación: Scopus.In this study we evaluated if zebrafish larvae can be colonized by human gut microorganisms. We tested two strategies: (1) through transplantation of a human fecal microbiota and (2) by successively transplanting aerotolerant anaerobic
Angelica Reyes-Jara +14 more
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Persistent systemic microbial translocation, inflammation, and intestinal damage during Clostridioides difficile infection [PDF]
, 2020 Background. Clostridioides difficile infection (CDI) might be complicated by the development of nosocomial bloodstream infection (n-BSI). Based on the hypothesis that alteration of the normal gut integrity is present during CDI, we evaluated markers of ...
Aversano, L. +13 more
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Porcine Colostrum Protects the IPEC-J2 Cells and Piglet Colon Epithelium against Clostridioides (syn. Clostridium) difficile Toxin-Induced Effects [PDF]
, 2020 Clostridioides difficile toxins are one of the main causative agents for the clinical symptoms observed during C. difficile infection in piglets. Porcine milk has been shown to strengthen the epithelial barrier function in the piglet’s intestine and may ...
Grześkowiak, Łukasz +7 more
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Editorial: Clostridioides difficile infection
Frontiers in MedicineGuido Granata +2 more
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Clostridioides difficile peptidoglycan modifications
Current Opinion in Microbiology, 2022 The cortex and peptidoglycan of Clostridioides difficile have been poorly investigated. This last decade, the interest increased because these two structures are highly modified and these modifications may be involved in antimicrobial resistance. For example, C.
Coullon, Héloïse, Candela, Thomas
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Plasmids of Clostridioides difficile
Current Opinion in Microbiology, 2022 Plasmids are ubiquitous in the bacterial world. In many microorganisms, plasmids have been implicated in important aspects of bacterial physiology and contribute to horizontal gene transfer. In contrast, knowledge on plasmids of the enteropathogen Clostridioides difficile is limited, and there appears to be no phenotypic consequence to carriage of many
Smits, W.K., Roseboom, A.M., Corver, J.
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Incidence and Outcomes Associated With Clostridium difficile Infections: A Systematic Review and Meta-analysis [PDF]
, 2020 Importance: An understanding of the incidence and outcomes of Clostridium difficile infection (CDI) in the United States can inform investments in prevention and treatment interventions.
Balkenende, Erin +15 more
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High sporulation and overexpression of virulence factors in biofilms and reduced susceptibility to vancomycin and linezolid in recurrent Clostridium [Clostridioides] difficile infection isolates [PDF]
, 2019 Clostridium [Clostridioides] difficile infection (CDI) is one of the leading causes of diarrhea associated with medical care worldwide, and up to 60% of patients with CDI can develop a recurrent infection (R-CDI). A multi-species microbiota biofilm model
Baines, Simon +9 more
core +2 more sources