Results 31 to 40 of about 168,874 (243)

Editorial for the Special Issue: Clostridium difficile

open access: yesMicroorganisms, 2021
Clostridium difficile (reclassified as Clostridioides difficile [...]
Łukasz M. Grześkowiak
doaj   +1 more source

Biochemical characterization of sporulation-related histidine kinases in Clostridioides difficile [PDF]

open access: yes, 2022
Histidine kinases are one of the two proteins that constitute a two-component signal transduction system. These systems are used by bacteria, fungi, and several plants to sense the conditions of their environment and alter their behavior to ensure ...
Shukla, Kriti
core  

Laboratory diagnostic methods for Clostridioides difficile infection [PDF]

open access: yes, 2023
Introduction. Clostridioides difficile is an anaerobic gram-positive, sporeforming, toxin-producing bacillus that is transmitted among humans through the fecal-oral route, as a result of ingestion of spores. Colonization of C. difficile is prevented by
Alexandrov, Anastasia
core  

Analysis of the impact of secondary prophylaxis on recurrence in critically ill adults

open access: yesSAGE Open Medicine, 2020
Introduction: Clostridioides (formerly Clostridium ) difficile infection recurrence in patients re-exposed to antibiotics for treatment of a non- Clostridioides difficile infection is high at approximately 33%. Low-dose per os vancomycin (e.g. 125 mg q12 
Kathryn A Connor, Kelly M Conn
doaj   +1 more source

Engineering probiotics to inhibit Clostridioides difficile infection by dynamic regulation of intestinal metabolism

open access: yesNature Communications, 2022
Clostridioides difficile infection (CDI) results in significant morbidity and mortality in hospitalised patients. Here the authors engineer probiotics to restore intestinal bile salt metabolism in response to antibiotic-induced microbiome dysbiosis ...
Elvin Koh   +7 more
doaj   +1 more source

Clostridioides difficile peptidoglycan modifications

open access: yesCurrent Opinion in Microbiology, 2022
The cortex and peptidoglycan of Clostridioides difficile have been poorly investigated. This last decade, the interest increased because these two structures are highly modified and these modifications may be involved in antimicrobial resistance. For example, C.
Coullon, Héloïse, Candela, Thomas
openaire   +4 more sources

In Vitro Activity of Omadacycline and Five Comparators against Contemporary Ribotypes of Clostridioides difficile in Stockholm, Sweden

open access: yesMicrobiology Spectrum, 2021
Clostridioides difficile infection represents a growing clinical challenge. The new compound omadacycline is a potential treatment alternative, as many antibiotics have limited activity or are rarely used due to costs and side effects.
Angela Camporeale   +4 more
doaj   +1 more source

Clostridioides difficile epidemiology in India

open access: yesAnaerobe, 2022
Clostridioides difficile infection (CDI) continues to affect hospitalized patients and community populations worldwide. In contrast to the substantial resources invested in the diagnosis and prevention of CDI in high-income countries, this anaerobic toxigenic bacterium has been largely overlooked in low-and-middle-income countries (LMICs) such as India,
Tanya M. Monaghan   +4 more
openaire   +2 more sources

Rare Clinical Association between Clostridioides difficile Infection and Ischemic Colitis: Case Report and Literature Review

open access: yesMedicina, 2021
Background and Objectives: Gut microbiota plays an important role in the wellbeing of the host through different interactions between microflora constituents. In certain instances, Clostridioides difficile may pullulate, causing infection with associated
Elena Mirela Ionescu   +6 more
doaj   +1 more source

Genomic characterization of nine Clostridioides difficile strains isolated from Korean patients with Clostridioides difficile infection

open access: yesGut Pathogens, 2021
Background Clostridioides difficile infection (CDI) is an infectious nosocomial disease caused by Clostridioides difficile, an opportunistic pathogen that occurs in the intestine after extensive antibiotic regimens. Results Nine C.
Seung Woo Ahn   +7 more
doaj   +1 more source

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