Results 31 to 40 of about 171,697 (237)

Faecal microbiota transplantation for first and second episode of Clostridioides difficile infection

open access: yes, 2023
Faecal microbiota transplantation is an accepted treatment for multiple recurrent Clostridioides difficile infections. 
Ed J Kuijper (9610556)   +4 more
core   +1 more source

Clostridioides difficile Infection: A Never-Ending Challenge

open access: yes, 2022
The most common worldwide cause of antibiotic-associated diarrhea/colitis is the toxin-producing bacterium Clostridioides difficile [...
Petrosillo, Nicola, Nicola Petrosillo
core   +1 more source

Engineering probiotics to inhibit Clostridioides difficile infection by dynamic regulation of intestinal metabolism

open access: yesNature Communications, 2022
Clostridioides difficile infection (CDI) results in significant morbidity and mortality in hospitalised patients. Here the authors engineer probiotics to restore intestinal bile salt metabolism in response to antibiotic-induced microbiome dysbiosis ...
Elvin Koh   +7 more
doaj   +1 more source

In Vitro Activity of Omadacycline and Five Comparators against Contemporary Ribotypes of Clostridioides difficile in Stockholm, Sweden

open access: yesMicrobiology Spectrum, 2021
Clostridioides difficile infection represents a growing clinical challenge. The new compound omadacycline is a potential treatment alternative, as many antibiotics have limited activity or are rarely used due to costs and side effects.
Angela Camporeale   +4 more
doaj   +1 more source

Clostridioides difficile epidemiology in India

open access: yesAnaerobe, 2022
Clostridioides difficile infection (CDI) continues to affect hospitalized patients and community populations worldwide. In contrast to the substantial resources invested in the diagnosis and prevention of CDI in high-income countries, this anaerobic toxigenic bacterium has been largely overlooked in low-and-middle-income countries (LMICs) such as India,
Tanya M. Monaghan   +4 more
openaire   +2 more sources

Clostridioides (Clostridium) difficile infection: Review of literature

open access: yes, 2022
Clostridioides (Clostridium) difficile (C. difficile) is a gram-positive bacterium that infects the large intestine. The number of clostridium difficile infections has increased in the recent years due to multiple risk factors including frequent use of ...
Varun Sodhi   +6 more
core   +1 more source

Rare Clinical Association between Clostridioides difficile Infection and Ischemic Colitis: Case Report and Literature Review

open access: yesMedicina, 2021
Background and Objectives: Gut microbiota plays an important role in the wellbeing of the host through different interactions between microflora constituents. In certain instances, Clostridioides difficile may pullulate, causing infection with associated
Elena Mirela Ionescu   +6 more
doaj   +1 more source

Chemical Inhibition of Pyocyanin Biosynthesis Attenuates Virulence of Pseudomonas aeruginosa

open access: yesAngewandte Chemie, EarlyView.
Anti‐virulence strategies disarm pathogens rather than killing them directly. A β‐lactone reduces pyocyanin production without affecting growth. Chemical proteomics identified PqsC as the primary target via binding to Cys129. Crystallography revealed the binding mode, and SAR yielded a chloroacetamide inhibitor with improved enzymatic potency and anti ...
Wei Ding   +3 more
wiley   +2 more sources

Genomic characterization of nine Clostridioides difficile strains isolated from Korean patients with Clostridioides difficile infection

open access: yesGut Pathogens, 2021
Background Clostridioides difficile infection (CDI) is an infectious nosocomial disease caused by Clostridioides difficile, an opportunistic pathogen that occurs in the intestine after extensive antibiotic regimens. Results Nine C.
Seung Woo Ahn   +7 more
doaj   +1 more source

Clostridioides Difficile Enteritis: Case Report and Literature Review

open access: yesAntibiotics, 2022
Background: Clostridioides Difficile is a well-known pathogen causing diarrhea of various degrees of severity through associated infectious colitis.
Artsiom Klimko   +6 more
doaj   +1 more source

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