Results 51 to 60 of about 171,697 (237)
Clostridioides difficile Flagella
International Journal of Molecular SciencesClostridioides difficile is an important pathogen for humans with a lead in nosocomial infection, but it is also more and more common in communities. Our knowledge of the pathology has historically been focused on the toxins produced by the bacteria that remain its major virulence factors.
Jean-Christophe Marvaud +3 more
openaire +2 more sources
Iron Regulation in Clostridioides difficile [PDF]
Frontiers in Microbiology, 2018 The response to iron limitation of several bacteria is regulated by the ferric uptake regulator (Fur). The Fur-regulated transcriptional, translational and metabolic networks of the Gram-positive, pathogen Clostridioides difficile were investigated by a combined RNA sequencing, proteomic, metabolomic and electron microscopy approach.
Mareike Berges +17 more
openaire +5 more sources
Antibiotics, 2019 Background: Oral vancomycin is a first line treatment for an initial episode of Clostridioides difficile infection. However, the comparative efficacy of different dosing regimens is lacking evidence in the current literature. Methods: We searched PubMed,
Chia-Yu Chiu +3 more
doaj +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Clostridioides difficile Infection [PDF]
Annals of Internal Medicine, 2018 Clostridioides difficile (formerly Clostridium difficile) infection is the most frequently identified health care-associated infection in the United States. C difficile has also emerged as a cause of community-associated diarrhea, resulting in increased incidence of community-associated infection.
Alice Y, Guh, Preeta K, Kutty
openaire +2 more sources
, 2023 Sandhya Nagarakanti, Robert Orenstein Division of Infectious Diseases, Mayo Clinic Arizona, Phoenix, AZ, USACorrespondence: Sandhya Nagarakanti, Mayo Clinic Arizona, Division of Infectious Diseases, 577 East Mayo Boulevard, Phoenix, AZ, 85054, USA, Tel ...
Nagarakanti S, Orenstein R
core
Artificial Intelligence‐Guided Phenotypic Drug Repurposing Against Streptococcus pneumoniae
Advanced Science, EarlyView.Integrated artificial intelligence (AI) ensembles identify highly potent repurposed drugs against Streptococcus pneumoniae. Prospective virtual screening of 6747 drugs uncovers nine active candidates, including thiostrepton. This drug exhibits low picomolar potency and bypasses established resistance in multidrug‐resistant strains, demonstrating an ...
Joshua S. Fitch +6 more
wiley +1 more source
, 2023 This thesis examines the effect of Clostridioides difficile (Clostridioides difficile should be italicized), an important bacterium that causes gastrointestinal disease, on the gastrointestinal tract.
CHRISTINE SZE LING ONG (16459776)
core +1 more source
Advanced Science, EarlyView.In collegiate endurance athletes, a 6‐week randomized CPYE intervention yielded time‐ and sex‐dependent shifts in field‐based cardiorespiratory, metabolic, and redox indices, accompanied by changes in gut multi‐omics profiles. An exploratory extension during intensified training generates hypotheses warranting future validation.
Meng Zhang +8 more
wiley +1 more source
Clostridioides difficile Infection: A Room for Multifaceted Interventions
, 2020 Clostridioides difficile (CD) continues to be the number one health care-associated infectious pathogen in the United States [...
Nicola Petrosillo, Maria Adriana Cataldo
core +1 more source