Results 61 to 70 of about 31,798 (219)

Update on commonly used molecular typing methods for Clostridioides Difficile [PDF]

, 2023
This review aims to provide a comprehensive overview of the significant Clostridioides difficile molecular typing techniques currently employed in research and medical communities.
Abad-Fau, Ana, Bolea, Rosa, Martín-Burriel, Inmaculada, Moreno, Bernardino, Sevilla, Eloísa   +4 more
core   +1 more source

The Role of Microbiota Metabolites Propionic Acid, p‐Cresol, and 4‐Ethylphenyl Sulfate in Autism Susceptibility: A Systematic Review

Autism Research, EarlyView.
ABSTRACT The etiopathogenesis of Autism Spectrum Disorder (ASD) encompasses complex interactions between genetic and environmental risk factors. The high prevalence of gastrointestinal disorders in autistic individuals has propelled a growing interest in the possible involvement of gut dysbiosis in ASD pathogenesis.
Laura Sandoni, Lisa Asta, Nicole Giompaolo, Rinvil Renaldi, Alberto Amaretti, Maddalena Rossi, Antonio M. Persico   +6 more
wiley   +1 more source

Newer Therapeutics to Selectively Kill Clostridioides difficile and Restore the Microbiome

Infectious Disease Reports
Background: The antibiotic ibezapolstat and the live biotherapeutic product live-JSLM are promising future approaches for treating Clostridioides difficile infection.
Guido Granata, Nicola Petrosillo
doaj   +1 more source

The Bacterial Gut Microbiota of Adult Patients Infected, Colonized or Noncolonized by Clostridioides difficile

Microorganisms, 2020
Gut microbiota composition in patients with Clostridioides difficile colonization is not well investigated. We aimed to identify bacterial signatures associated with resistance and susceptibility to C.
Monique J. T. Crobach, Quinten R. Ducarmon, Elisabeth M. Terveer, Celine Harmanus, Ingrid M. J. G. Sanders, Kees M. Verduin, Ed J. Kuijper, Romy D. Zwittink   +7 more
doaj   +1 more source

Deliverable D-JRP15–FED-AMR-WP3.2: Overview of genetic overlap between human and non-human Clostridiodes difficile isolates [PDF]

, 2022
This deliverable and the associated task aims to contribute to increase knowledge regarding the true impact of C. difficile as a zoonotic agent and its transmission networks, by evaluating the extent of genetic overlap and potential transmission between ...
Abdel-Glil, Mostafa Youssef, Alves, Frederico, Cabal Rosel, Adriana, Castro, Rita, Dost, Ines, Maurischat, Sven, Mazuet, Christelle, Oleastro, Monica, Persson, Soren, Schlotzek, Anissa, Seyboldt, Christian, Tenson, Tanel   +11 more
core   +2 more sources

Serious Infection in Crohn's Disease Patients Treated With Ustekinumab: US Food and Drug Administration Active Postmarket Risk Identification and Analysis in the Sentinel Initiative

Clinical Pharmacology &Therapeutics, EarlyView.
The U.S. Food and Drug Administration (FDA) used an Active Postmarket Risk Identification and Analysis (ARIA) system to address a safety issue (serious infection) identified during clinical review of an application to market ustekinumab as a treatment for Crohn's disease (CD). FDA used an active‐comparator new‐user cohort design, data from six Sentinel
Joel L. Weissfeld, Geetha S. Iyer, Suna C. Seo, Andrew Giffin, Andrew L. Simon, Sheryl A. Kluberg, Emma R. Hoffman, Jamal T. Jones, Sarah K. Dutcher, Joyce A. Korvick   +9 more
wiley   +1 more source

Recommendations for the management of Clostridioides difficile infection in adults and comparison with updated ACG, ESCMID and IDSA/SHEA guidelines

Family Medicine & Primary Care Review
Clostridioides difficile infection is the most common cause of antibiotic-associated diarrhea. IDSA/SHEA, ESCMID and ACG updated the clinical practice guidelines for CDI in 2021. This paper is an attempt to summarize these guidelines.
Mateusz Piotr Baran, Jarosław Drobnik, Mária Belovičová, Štefánia Moricová, Piotr Pobrotyn   +4 more
doaj   +1 more source

Satellites in the prokaryote world [PDF]

, 2019
Background Satellites or tandem repeats are very abundant in many eukaryotic genomes. Occasionally they have been reported to be present in some prokaryotes, but to our knowledge there is no general comparative study on their occurrence.
Messeguer Peypoch, Xavier, Subirana Torrent, Juan A.   +1 more
core   +2 more sources

Underutilization of syndrome‐specific ICD‐10 codes for genetic epilepsies: Implications for precision medicine

Epilepsia, EarlyView.
Abstract Syndrome‐specific International Classification of Diseases, 10th Revision (ICD‐10) codes have the potential to improve identification of patients for precision therapies, clinical trials, and research, yet their real‐world uptake is not well characterized.
Émile Moura Coelho da Silva, Tobias Brünger, Gary Taylor, Mousumi Sinha, Alison Merket, Anu Cherukara, Sunanjay Bajaj, Jessica Clark, Ludovica Montanucci, Emily A. Huth, Mariana Fauteux, Samden D. Lhatoo, Christian M. Boßelmann, Costin Leu, Rahil A. Tai, Dennis Lal   +15 more
wiley   +1 more source

Mortality Attributable to Clostridioides difficile Infection: The Rising Burden of Disease in European Countries

Medicina
Background and Objectives: Clostridioides difficile infection is a major public health issue, being among the main causes of mortality due to healthcare-associated diarrhea.
Irena Ilic, Ivana Zivanovic Macuzic, Milena Ilic   +2 more
doaj   +1 more source