Faecal microbiota transplantation for first and second episode of Clostridioides difficile infection [PDF]
, 2023 Faecal microbiota transplantation is an accepted treatment for multiple recurrent Clostridioides difficile infections.
Ed J Kuijper (9610556) +4 more
core +2 more sources
Beneficial effects of fecal microbiota transplantation in recurrent Clostridioides difficile infection [PDF]
, 2023 Fecal microbiota transplantation (FMT) is highly effective in preventing recurrent Clostridioides difficile infection (rCDI). However, the mechanisms underpinning its clinical efficacy are incompletely understood.
Seekatz, Anna M. +19 more
core +2 more sources
Biochemical characterization of sporulation-related histidine kinases in Clostridioides difficile [PDF]
, 2022 Histidine kinases are one of the two proteins that constitute a two-component signal transduction system. These systems are used by bacteria, fungi, and several plants to sense the conditions of their environment and alter their behavior to ensure ...
Shukla, Kriti
core
Laboratory diagnostic methods for Clostridioides difficile infection [PDF]
, 2023 Introduction. Clostridioides difficile is an anaerobic gram-positive, sporeforming, toxin-producing bacillus that is transmitted among humans through the fecal-oral route, as a result of ingestion of spores. Colonization of C. difficile is prevented by
Alexandrov, Anastasia
core
Analysis of the impact of secondary prophylaxis on recurrence in critically ill adults
SAGE Open Medicine, 2020 Introduction: Clostridioides (formerly Clostridium ) difficile infection recurrence in patients re-exposed to antibiotics for treatment of a non- Clostridioides difficile infection is high at approximately 33%. Low-dose per os vancomycin (e.g. 125 mg q12
Kathryn A Connor, Kelly M Conn
doaj +1 more source
Characterization of the gut microbiome of patients with Clostridioides difficile infection, patients with non–C. difficile diarrhea, and C. difficile–colonized patients [PDF]
, 2023 Funding: This study was funded by Fondo de Investigaciones Sanitarias (FIS), Research Project number PI16/00490 and PI20/01381, PFIS grant number FI21/00310, and by the European Regional Development Fund (FEDER) “A way of making Europe”.Introduction ...
Vázquez Cuesta, Silvia +9 more
core +1 more source
Nature Communications, 2022 Clostridioides difficile infection (CDI) results in significant morbidity and mortality in hospitalised patients. Here the authors engineer probiotics to restore intestinal bile salt metabolism in response to antibiotic-induced microbiome dysbiosis ...
Elvin Koh +7 more
doaj +1 more source
Microbiology Spectrum, 2021 Clostridioides difficile infection represents a growing clinical challenge. The new compound omadacycline is a potential treatment alternative, as many antibiotics have limited activity or are rarely used due to costs and side effects.
Angela Camporeale +4 more
doaj +1 more source
Treating Clostridioides difficile: Could Microbiota-based Live Biotherapeutic Products Provide the Answer? [PDF]
, 2023 Sandhya Nagarakanti, Robert Orenstein Division of Infectious Diseases, Mayo Clinic Arizona, Phoenix, AZ, USACorrespondence: Sandhya Nagarakanti, Mayo Clinic Arizona, Division of Infectious Diseases, 577 East Mayo Boulevard, Phoenix, AZ, 85054, USA, Tel ...
Nagarakanti S, Orenstein R
core
Clostridioides difficile peptidoglycan modifications
Current Opinion in Microbiology, 2022 The cortex and peptidoglycan of Clostridioides difficile have been poorly investigated. This last decade, the interest increased because these two structures are highly modified and these modifications may be involved in antimicrobial resistance. For example, C.
Coullon, Héloïse, Candela, Thomas
openaire +4 more sources