Results 21 to 30 of about 168,874 (243)

Variants at the MHC Region Associate With Susceptibility to Clostridioides difficile Infection: A Genome-Wide Association Study Using Comprehensive Electronic Health Records

Frontiers in Immunology, 2021
BackgroundClostridioides difficile is a major cause of healthcare-associated and community-acquired diarrhea. Host genetic susceptibility to Clostridioides difficile infection has not been studied on a large-scale.MethodsA total of 1,160 Clostridioides ...
Jiang Li, Yanfei Zhang, Alexandria L. Jilg, Donna M. Wolk, Harshit S. Khara, Amy Kolinovsky, David D. K. Rolston, Raquel Hontecillas, Josep Bassaganya-Riera, Marc S. Williams, Vida Abedi, Ming Ta Michael Lee   +11 more
doaj   +1 more source

Molecular epidemiology and antimicrobial resistance of Clostridioides difficile detected in chicken, soil and human samples from Zimbabwe

International Journal of Infectious Diseases, 2020
Background: Clostridioides difficile is the major cause of infectious nosocomial diarrhoea in industrialized nations. Data on the occurrence of C. difficile in Africa, ribotype (RT) distribution, antimicrobial susceptibility patterns and potential ...
Fabian K. Berger, Alexander Mellmann, Markus Bischoff, Lutz von Müller, Sören L. Becker, Clifford Simango, Barbara Gärtner   +6 more
doaj   +1 more source

IL-27 induces LL-37/CRAMP expression from intestinal epithelial cells: implications for immunotherapy of Clostridioides difficile infection

Gut Microbes, 2021
Clostridioides difficile infection is currently the leading cause of nosocomial antibiotic-associated diarrhea and pseudomembranous colitis worldwide. Cathelicidins, a major group of natural antimicrobial peptides, have antimicrobial and immunomodulatory
Banglao Xu, Xianan Wu, Yi Gong, Ju Cao
doaj   +1 more source

Epidemiology of Clostridioides difficile Infection in Portugal: A Retrospective, Observational Study of Hospitalized Patients

Acta Médica Portuguesa, 2022
Introduction: Clostridioides difficile is the main cause of healthcare-associated diarrhea in Europe and North America. The aim of this study was to characterize the epidemiology and clinical burden of Clostridioides difficile infection among ...
Cláudia Nazareth, Inês Leitão, Ernestina Reis, Hugo Inácio, Filomena Martins, Elmano Ramalheira, Flávia Cunha, Carla Santos, Sara Lino, Hugo Moreira, Nadiya Kruptsala, Andrea Santos, Laura Paixão, Leonor Pássaro, Mónica Oleastro   +14 more
doaj   +1 more source

Faecal microbiota transplantation for first and second episode of Clostridioides difficile infection

, 2023
Faecal microbiota transplantation is an accepted treatment for multiple recurrent Clostridioides difficile infections. 
Ed J Kuijper (9610556), Joffrey van Prehn (14673381), European Study Group for Clostridioides difficile (14691179), European Study Group for Host and Microbiota Interaction (14691180), Fidelma Fitzpatrick (7895483)   +4 more
core   +3 more sources

Mortality Following Clostridioides difficile Infection in Europe: A Retrospective Multicenter Case-Control Study [PDF]

, 2021
Infecció per Clostridioides difficile; Mortalitat; Factors de riscInfección por Clostridioides difficile; Mortalidad; Factores de riesgoClostridioides difficile infection; Mortality; Risk factorsWe aimed to describe the clinical presentation, treatment ...
Mizrahi, Assaf, Khanafer, Nagham, Krutova, Marcela, Nuvials Casals, Xavier, Patyi, Márta, Czepiel, Jacek, Enoch, David A.   +6 more
core   +1 more source

European Society of Clinical Microbiology and Infectious Diseases:2021 update on the treatment guidance document for Clostridioides difficile infection in adults [PDF]

, 2021
SCOPE: In 2009, the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) published the first treatment guidance document for Clostridioides difficile infection (CDI). This document was updated in 2014.
Guery, B., Wilcox, M.H., Hristea, A, Goorhuis, A, Tschudin-Sutter, S, Kuijper, E J, Coia, J; id_orcid, Bouza, E, van Rossen, T.M., Wilcox, M H, Allerberger, F, Vehreschild, M, Bouza, E., van Rossen, T M, Reigadas, E, van Prehn, J, Scharvik Olesen, B R, Norén, T., Allerberger, F., Ooijevaar, R.E., Scharvik Olesen, B.R., Burns, K, Ooijevaar, R E, van Prehn, J., Burns, K., Tschudin-Sutter, S., Krutova, M, Vogelzang, E.H., Hristea, A., Goorhuis, A., Fitzpatrick, F., Coia, J.E., Guery, B, Vehreschild, MJGT, Norén, T, Fitzpatrick, F, Krutova, M., Vogelzang, E H, Reigadas, E., Kuijper, E.J.   +39 more
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Clostridioides difficile infections: Preventive strategies [PDF]

, 2023
Clostridioides difficile infections primarily affect elderly, hospitalised patients treated with antibiotics and are among the most common healthcare-related infections. This thesis aimed to improve the understanding of the best prevention strategies for
Edman Wallér, Jon
core   +1 more source

Does Fecal Microbiota Transplant Have a Role in Treating Recurrent Clostridioides difficile Infection in Rural Hospitals?

Frontiers in Public Health, 2021
Clostridioides difficile infection possesses a significant economical burden, specifically in the inpatient and rural settings. Fecal Microbiota Transplant has been used for treatment of recurrent Clostridioides difficile but its utility is limited by ...
Krishna Vedala, Philip Sobash, Parth Shah, Gilbert-Roy Kamoga   +3 more
doaj   +1 more source

Beneficial effects of fecal microbiota transplantation in recurrent Clostridioides difficile infection [PDF]

, 2023
Fecal microbiota transplantation (FMT) is highly effective in preventing recurrent Clostridioides difficile infection (rCDI). However, the mechanisms underpinning its clinical efficacy are incompletely understood.
Seekatz, Anna M., Karen Wong, Tanya M. Monaghan, Dina Kao, Abbas Yadegar, Wong, Karen, Laura Cook, Walter, Jens, Ali Nabavi-Rad, Anna M. Seekatz, Kao, Dina, Monaghan, Tanya M., Cook, Laura, Jens Walter, Nabavi-Rad, Ali, Ibrahim, Fathima F., Pakpoor, Sepideh F., Sepideh Pakpoor, Fathima F. Ibrahim, Yadegar, Abbas   +19 more
core   +1 more source