Results 21 to 30 of about 171,697 (237)

Variants at the MHC Region Associate With Susceptibility to Clostridioides difficile Infection: A Genome-Wide Association Study Using Comprehensive Electronic Health Records

Frontiers in Immunology, 2021
BackgroundClostridioides difficile is a major cause of healthcare-associated and community-acquired diarrhea. Host genetic susceptibility to Clostridioides difficile infection has not been studied on a large-scale.MethodsA total of 1,160 Clostridioides ...
Jiang Li, Yanfei Zhang, Alexandria L. Jilg, Donna M. Wolk, Harshit S. Khara, Amy Kolinovsky, David D. K. Rolston, Raquel Hontecillas, Josep Bassaganya-Riera, Marc S. Williams, Vida Abedi, Ming Ta Michael Lee   +11 more
doaj   +1 more source

Molecular epidemiology and antimicrobial resistance of Clostridioides difficile detected in chicken, soil and human samples from Zimbabwe

International Journal of Infectious Diseases, 2020
Background: Clostridioides difficile is the major cause of infectious nosocomial diarrhoea in industrialized nations. Data on the occurrence of C. difficile in Africa, ribotype (RT) distribution, antimicrobial susceptibility patterns and potential ...
Fabian K. Berger, Alexander Mellmann, Markus Bischoff, Lutz von Müller, Sören L. Becker, Clifford Simango, Barbara Gärtner   +6 more
doaj   +1 more source

IL-27 induces LL-37/CRAMP expression from intestinal epithelial cells: implications for immunotherapy of Clostridioides difficile infection

Gut Microbes, 2021
Clostridioides difficile infection is currently the leading cause of nosocomial antibiotic-associated diarrhea and pseudomembranous colitis worldwide. Cathelicidins, a major group of natural antimicrobial peptides, have antimicrobial and immunomodulatory
Banglao Xu, Xianan Wu, Yi Gong, Ju Cao
doaj   +1 more source

Epidemiology of Clostridioides difficile Infection in Portugal: A Retrospective, Observational Study of Hospitalized Patients

Acta Médica Portuguesa, 2022
Introduction: Clostridioides difficile is the main cause of healthcare-associated diarrhea in Europe and North America. The aim of this study was to characterize the epidemiology and clinical burden of Clostridioides difficile infection among ...
Cláudia Nazareth, Inês Leitão, Ernestina Reis, Hugo Inácio, Filomena Martins, Elmano Ramalheira, Flávia Cunha, Carla Santos, Sara Lino, Hugo Moreira, Nadiya Kruptsala, Andrea Santos, Laura Paixão, Leonor Pássaro, Mónica Oleastro   +14 more
doaj   +1 more source

Does Fecal Microbiota Transplant Have a Role in Treating Recurrent Clostridioides difficile Infection in Rural Hospitals?

Frontiers in Public Health, 2021
Clostridioides difficile infection possesses a significant economical burden, specifically in the inpatient and rural settings. Fecal Microbiota Transplant has been used for treatment of recurrent Clostridioides difficile but its utility is limited by ...
Krishna Vedala, Philip Sobash, Parth Shah, Gilbert-Roy Kamoga   +3 more
doaj   +1 more source

Mortality Following Clostridioides difficile Infection in Europe: A Retrospective Multicenter Case-Control Study [PDF]

, 2021
Infecció per Clostridioides difficile; Mortalitat; Factors de riscInfección por Clostridioides difficile; Mortalidad; Factores de riesgoClostridioides difficile infection; Mortality; Risk factorsWe aimed to describe the clinical presentation, treatment ...
Mizrahi, Assaf, Khanafer, Nagham, Krutova, Marcela, Nuvials Casals, Xavier, Patyi, Márta, Czepiel, Jacek, Enoch, David A.   +6 more
core   +1 more source

Applications of Fecal Microbiota Transplantation: Emphasis on Clostridioides difficile Infections [PDF]

, 2021
Objective: This study aimed to perform a comprehensive review of clinical trials using fecal microbiota transplantation in cases of Clostridioides difficile infection.
Longo, Priscila Larcher, Montiel, José Maria, Oliveira, Rômulo Tadeu Dias de, Signorette, Juliana Peloso, Priscila Larcher Longo, Juliana Peloso Signorette, Rômulo Tadeu Dias de Oliveira, José Maria Montiel   +7 more
core   +1 more source

Analysis of the impact of secondary prophylaxis on recurrence in critically ill adults

SAGE Open Medicine, 2020
Introduction: Clostridioides (formerly Clostridium ) difficile infection recurrence in patients re-exposed to antibiotics for treatment of a non- Clostridioides difficile infection is high at approximately 33%. Low-dose per os vancomycin (e.g. 125 mg q12 
Kathryn A Connor, Kelly M Conn
doaj   +1 more source

Editorial for the Special Issue: Clostridium difficile

Microorganisms, 2021
Clostridium difficile (reclassified as Clostridioides difficile [...]
Łukasz M. Grześkowiak
doaj   +1 more source

Clostridioides difficile peptidoglycan modifications

Current Opinion in Microbiology, 2022
The cortex and peptidoglycan of Clostridioides difficile have been poorly investigated. This last decade, the interest increased because these two structures are highly modified and these modifications may be involved in antimicrobial resistance. For example, C.
Coullon, Héloïse, Candela, Thomas
openaire   +4 more sources