Persistent systemic microbial translocation, inflammation, and intestinal damage during Clostridioides difficile infection [PDF]
, 2020 Background. Clostridioides difficile infection (CDI) might be complicated by the development of nosocomial bloodstream infection (n-BSI). Based on the hypothesis that alteration of the normal gut integrity is present during CDI, we evaluated markers of ...
Aversano, L. +13 more
core +1 more source
Applications of Fecal Microbiota Transplantation: Emphasis on Clostridioides difficile Infections [PDF]
, 2022 Objective: This study aimed to perform a comprehensive review of clinical trials using fecal microbiota transplantation in cases of Clostridioides difficile infection.
Longo, Priscila Larcher +3 more
core +2 more sources
Editorial for the Special Issue: Clostridium difficile
Microorganisms, 2021 Clostridium difficile (reclassified as Clostridioides difficile [...]
Łukasz M. Grześkowiak
doaj +1 more source
Porcine Colostrum Protects the IPEC-J2 Cells and Piglet Colon Epithelium against Clostridioides (syn. Clostridium) difficile Toxin-Induced Effects [PDF]
, 2020 Clostridioides difficile toxins are one of the main causative agents for the clinical symptoms observed during C. difficile infection in piglets. Porcine milk has been shown to strengthen the epithelial barrier function in the piglet’s intestine and may ...
Grześkowiak, Łukasz +7 more
core +1 more source
Clostridioides difficile, a New “Superbug”
Microorganisms, 2023 Clostridioides difficile is a Gram-positive, spore-forming, anaerobic bacterium. The clinical features of C. difficile infections (CDIs) can vary, ranging from the asymptomatic carriage and mild self-limiting diarrhoea to severe and sometimes fatal pseudomembranous colitis. C.
Rumyana Markovska +3 more
openaire +3 more sources
Detection of potential enteric pathogens in children with severe acute gastroenteritis using the filmarray: Results from a three - years hospital-based survey in Northern Italy [PDF]
, 2022 Acute gastroenteritis (AGE) are leading causes of morbidity and mortality in children. Therefore, rapid pathogens identification is needed. The AGE aetiology was investigated from 2018 to 2020 in 2,066 children in Parma (Italy) by FilmArray ...
Arcangeletti M. C. +6 more
core +1 more source
SplitStrains, a tool to identify and separate mixed Mycobacterium tuberculosis infections from WGS data [PDF]
Microbial Genomics, 7, 2021, 6, 2022 The occurrence of multiple strains of a bacterial pathogen such as M. tuberculosis or C. difficile within a single human host, referred to as a mixed infection, has important implications for both healthcare and public health. However, methods for detecting it, and especially determining the proportion and identities of the underlying strains, from WGS
arxiv +1 more source
Swiss expert opinion: current approaches in faecal microbiota transplantation in daily practice [PDF]
, 2023 INTRODUCTION Faecal microbiota transplantation (FMT) is an established therapy for recurrent C. difficile infection, and recent studies have reported encouraging results of FMT in patients with ulcerative colitis.
Burri, Emanuel +10 more
core +1 more source
Nature Communications, 2022 Clostridioides difficile infection (CDI) results in significant morbidity and mortality in hospitalised patients. Here the authors engineer probiotics to restore intestinal bile salt metabolism in response to antibiotic-induced microbiome dysbiosis ...
Elvin Koh +7 more
doaj +1 more source
Microbiology Spectrum, 2021 Clostridioides difficile infection represents a growing clinical challenge. The new compound omadacycline is a potential treatment alternative, as many antibiotics have limited activity or are rarely used due to costs and side effects.
Angela Camporeale +4 more
doaj +1 more source