Results 51 to 60 of about 31,246 (217)

Epidemiology of Clostridioides difficile Infections in Germany, 2010–2019: A Review from Four Public Databases

open access: yesInfectious Diseases and Therapy, 2023
Introduction Clostridioides difficile infection (CDI) is a recognized global threat especially for vulnerable populations. It is of particular concern to healthcare providers as it is found in both hospital and community settings, with severe courses ...
Gordon Brestrich   +15 more
doaj   +1 more source

Clostridioides difficile Flagella

open access: yesInternational Journal of Molecular Sciences
Clostridioides difficile is an important pathogen for humans with a lead in nosocomial infection, but it is also more and more common in communities. Our knowledge of the pathology has historically been focused on the toxins produced by the bacteria that remain its major virulence factors.
Jean-Christophe Marvaud   +3 more
openaire   +2 more sources

Phages and human health: More than idle hitchhikers [PDF]

open access: yes, 2019
Bacteriophages, or phages, are viruses that infect bacteria and archaea. Phages have diverse morphologies and can be coded in DNA or RNA and as single or double strands with a large range of genome sizes. With the increasing use of metagenomic sequencing
Baldridge, Megan T   +2 more
core   +2 more sources

Uncovering the Harms of Treating Clostridioides difficile Colonization

open access: yesmSphere, 2021
Patients with toxin-negative Clostridioides ...
Christopher R. Polage   +1 more
doaj   +1 more source

Deliverable D-JRP15–FED-AMR-WP3.2: Overview of genetic overlap between human and non-human Clostridiodes difficile isolates [PDF]

open access: yes, 2022
This deliverable and the associated task aims to contribute to increase knowledge regarding the true impact of C. difficile as a zoonotic agent and its transmission networks, by evaluating the extent of genetic overlap and potential transmission between ...
Abdel-Glil, Mostafa Youssef   +11 more
core   +2 more sources

Prospective Review of Clostridioides difficile Testing Indications to Inform Local Laboratory Stewardship Initiatives

open access: yesInfection Prevention in Practice, 2019
Summary: We conducted a prospective chart review to determine the prevalence of and reasons for inappropriate Clostridioides difficile test-ordering at a tertiary care hospital. Inappropriate orders accounted for 54% of all tests.
Noah Reich   +7 more
doaj   +1 more source

Clostridioides difficile Enteritis Induced Anastomotic Rupture: A Case Report and Literature Review

open access: yesCase Reports in Surgery, 2020
Background. A 76-year-old male patient who suffered small bowel anastomotic dehiscence believed to be a complication provoked by Clostridioides difficile enteritis. Case Presentation. The patient was a 76-year-old male who underwent small bowel resection
David R. Velez, Mentor Ahmeti
doaj   +1 more source

Gut Microbiota‐Non‐Coding RNA Axis in Immune Modulation and Disease: From Mechanisms to Clinical Translation

open access: yesAdvanced Science, EarlyView.
ABSTRACT Immune homeostasis is indispensable for preserving organismal integrity, orchestrated through complex molecular networks encompassing immune cell dynamics, microbial cues, and epigenetic regulation. Among these, the gut microbiota‐non‐coding RNA (ncRNA) axis has recently garnered substantial attention as a multifaceted modulator of host ...
Bonan Chen   +12 more
wiley   +1 more source

Freeze-dried fecal samples are biologically active after long-lasting storage and suited to fecal microbiota transplantation in a preclinical murine model of Clostridioides difficile infection

open access: yesGut Microbes, 2020
Fecal microbiota transplantation is now recommended for treating recurrent forms of Clostridioides difficile infection. Recent studies have reported protocols using capsules of either frozen or freeze-dried stool allowing oral administration in in- and ...
Julie Reygner   +14 more
doaj   +1 more source

Impact of Prophylactic Cefepime on Surgical Site Infection and Severe Morbidity in Patients Who Underwent Pancreaticoduodenectomy With Preoperative Biliary Drainage

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Although prophylactic broad‐spectrum antibiotics can reduce postoperative complications after pancreaticoduodenectomy (PD), the optimal regimen remains uncertain. This study evaluated the impact of prophylactic cefepime (CFPM) on surgical site infection (SSI) and severe morbidity after PD with preoperative biliary drainage.
Genki Watanabe   +8 more
wiley   +1 more source

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