Results 81 to 90 of about 34,117 (261)

Impact of ribotype on Clostridioides difficile diagnostics [PDF]

European Journal of Clinical Microbiology & Infectious Diseases, 2019
AbstractThis study investigates the performance of diagnostic methods for detection of Clostridioides difficile infection in Sweden, including impact of PCR ribotype on diagnostic performance. Between 2011 and 2016, a total of 17,878 stool samples from 26 laboratories were tested by either well-type enzyme immunoassays (EIAs), membrane bound EIAs, cell
Kristina Rizzardi, Andreas Matussek, Thomas Åkerlund, Torbjörn Norén   +3 more
openaire   +3 more sources

Sentinel surveillance and epidemiology of Clostridioides difficile in Denmark, 2016 to 2019 [PDF]

, 2022
BACKGROUND: Since 2008, Danish national surveillance of Clostridioides difficile has focused on binary toxin-positive strains in order to monitor epidemic types such as PCR ribotype (RT) 027 and 078.
Andersen, Leif Percival, Coia, John Eugenio, Engberg, Jørgen, Engsbro, Anne Line, Holt, Hanne Marie, Jensen, Mie Birgitte Frid, Lemming, Lars, Marmolin, Ea Sofie, Nielsen, Eva Møller, Nielsen, Hans Linde, Nielsen, Sofie Holtsmark, Olesen, Bente Scharvik, Persson, Søren, Petersen, Andreas Munk, Søndergaard, Turid Snekloth, Sørensen, Gitte, Wiuf, Camilla   +16 more
core   +1 more source

Advances in Small Molecule Inhibitors Targeting the Bacterial Lipoprotein Transport System (Lol) in Gram‐Negative Bacteria

Chemistry – An Asian Journal, EarlyView.
The lipoprotein transport system (Lol) is a crucial target for combating multidrug‐resistant gram‐negative bacteria. This review discusses the structural and functional aspects of the LolABCDE complex, recent advances in small‐molecule inhibitors, and challenges, such as permeability and resistance.
Saemee Song, Su Yong Shim
wiley   +1 more source

Recommendations for the management of Clostridioides difficile infection in adults and comparison with updated ACG, ESCMID and IDSA/SHEA guidelines

Family Medicine & Primary Care Review
Clostridioides difficile infection is the most common cause of antibiotic-associated diarrhea. IDSA/SHEA, ESCMID and ACG updated the clinical practice guidelines for CDI in 2021. This paper is an attempt to summarize these guidelines.
Mateusz Piotr Baran, Jarosław Drobnik, Mária Belovičová, Štefánia Moricová, Piotr Pobrotyn   +4 more
doaj   +1 more source

An incidental finding of mesenteric hematoma in a patient with a new diagnosis of inflammatory bowel disease

JPGN Reports, EarlyView.
Abstract Mesenteric hematomas (MHs) are relatively rare and are characterized by localized bleeding in the mesenteric vascular tree presenting with abdominal pain, vomiting, abdominal distension, masses, and hypotension. We report a case of a MH which was incidentally found in a 10‐year‐old patient with a new diagnosis of ulcerative colitis (UC).
Breanna Brown, Anna Hunter, Kimberly Trieschmann   +2 more
wiley   +1 more source

Update on Treatment of Clostridioides difficile Infection [PDF]

Mayo Clinic Proceedings, 2020
Clostridioides difficile infection (CDI) is the leading cause of health care-associated infections in the United States. The increasing incidence and recurrence rates of CDI together with its associated morbidity and mortality are great concerns.
Janice M. Cho, Darrell S. Pardi, Sahil Khanna   +2 more
openaire   +2 more sources

Mortality Attributable to Clostridioides difficile Infection: The Rising Burden of Disease in European Countries

Medicina
Background and Objectives: Clostridioides difficile infection is a major public health issue, being among the main causes of mortality due to healthcare-associated diarrhea.
Irena Ilic, Ivana Zivanovic Macuzic, Milena Ilic   +2 more
doaj   +1 more source

Clostridioides difficile infection in a long-term convalescence hospital: A real tale of pitfalls and outdated therapy [PDF]

, 2021
Objective. The aim of the study was to know the char-acteristics and risk factors of Clostridioides difficile infection (CDI) in a long-term hospital is key to improve its manage-ment. Material and methods.
Esteban-Rihuete, M., García-Forcada, Á., García-Herrero, J.C., García-Lechuz, J.M., Moreno-Borraz, L., Rodríguez-Gascón, D.   +5 more
core   +1 more source

Case Studies of Orphan Domain Reclassification in ECOD by Expert Curation

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Homology‐based protein domain classification is a powerful tool for gaining biological insights into protein function. This classification process has been significantly enhanced by the availability of experimental structures and high‐accuracy structural models generated by advanced tools such as AlphaFold.
Jimin Pei, R. Dustin Schaeffer, Qian Cong, Nick V. Grishin   +3 more
wiley   +1 more source

Overview of current detection methods and microRNA potential in Clostridioides difficile infection screening [PDF]

, 2023
Clostridioides difficile (formerly called Clostridium difficile, C. difficile) infection (CDI) is listed as an urgent threat on the 2019 antibiotic resistance threats report in the United States by the Centers for Disease Control and Prevention.
Bocchetti, Marco, Cossu, Alessia Maria, Ferraro, Maria Grazia, Grisolia, Piera, Melisi, Federica, Scrima, Marianna, Yau, Tung On   +6 more
core   +1 more source