Results 81 to 90 of about 31,421 (293)
Family Medicine & Primary Care ReviewClostridioides difficile infection is the most common cause of antibiotic-associated diarrhea. IDSA/SHEA, ESCMID and ACG updated the clinical practice guidelines for CDI in 2021. This paper is an attempt to summarize these guidelines.
Mateusz Piotr Baran +4 more
doaj +1 more source
DETCID: Detection of Elongated Touching Cells with Inhomogeneous Illumination using a Deep Adversarial Network [PDF]
arXiv, 2020 Clostridioides difficile infection (C. diff) is the most common cause of death due to secondary infection in hospital patients in the United States. Detection of C. diff cells in scanning electron microscopy (SEM) images is an important task to quantify the efficacy of the under-development treatments. However, detecting C.
arxiv
Microbial Biosensor for Sensing and Treatment of Intestinal Inflammation
Advanced Science, EarlyView.The engineered calprotectin biosensor detects gut inflammation, processes the signal through genetic regulation, and responds by expressing the reporter sfGFP and the therapeutic protein secIL10. This dual functionality enables the engineered biosensor not only to sense but also to mitigate gut inflammation, highlighting its potential for disease ...
Duolong Zhu +8 more
wiley +1 more source
MedicinaBackground and Objectives: Clostridioides difficile infection is a major public health issue, being among the main causes of mortality due to healthcare-associated diarrhea.
Irena Ilic +2 more
doaj +1 more source
Clostridioides difficile Flagella
International Journal of Molecular SciencesClostridioides difficile is an important pathogen for humans with a lead in nosocomial infection, but it is also more and more common in communities. Our knowledge of the pathology has historically been focused on the toxins produced by the bacteria that remain its major virulence factors.
Jean-Christophe Marvaud +3 more
openaire +2 more sources
Synthetic Biology‐Based Engineering Living Therapeutics for Antimicrobial Application
Exploration, EarlyView.This perspective highlights synthetic biology‐driven antibacterial strategies, focusing on three innovative approaches: engineered bacteriophages for precision bacterial targeting, reprogrammed microbes that detect quorum‐sensing signals or metabolites to release antimicrobials, and engineering mammalian cells that recognize pathogen‐associated ...
Shun Huang +4 more
wiley +1 more source
Concurrent and Subsequent Co-Infections of Clostridioides difficile Colitis in the Era of Gut Microbiota and Expanding Treatment Options [PDF]
, 2022 We narratively reviewed the physiopathology, epidemiology, and management of co-infections in Clostridioides difficile colitis (CDI) by searching the following keywords in Embase, MedLine, and PubMed: “Clostridium/Clostridioides difficile”, “co-infection”
Bonora, Stefano +5 more
core +1 more source
mSphere, 2021 Diarrheal samples from patients taking laxatives are typically rejected for Clostridioides difficileC ...
Sarah Tomkovich +9 more
doaj +1 more source
Impact of ribotype on Clostridioides difficile diagnostics [PDF]
European Journal of Clinical Microbiology & Infectious Diseases, 2019 AbstractThis study investigates the performance of diagnostic methods for detection of Clostridioides difficile infection in Sweden, including impact of PCR ribotype on diagnostic performance. Between 2011 and 2016, a total of 17,878 stool samples from 26 laboratories were tested by either well-type enzyme immunoassays (EIAs), membrane bound EIAs, cell
Kristina Rizzardi +3 more
openaire +3 more sources
Enhancing human gut health: Global innovations in dysbiosis management
iMeta, EarlyView.The microbiota, comprising all the microorganisms within the body, plays a critical role in maintaining good health. Dysbiosis represents a condition resulting from an imbalance or alteration of the microbiota. This study comprehensively investigates the patent literature on dysbiosis over the past 20 years.
Reda El Boukhari +66 more
wiley +1 more source