Results 141 to 150 of about 44,840 (262)

Toxigenic profiles of clinical Clostridioides difficile in public and private healthcare settings in Gauteng, South Africa

International Journal of Infectious Diseases
Introduction: Clostridioides difficile infection (CDI) is a serious healthcare-associated infection causing life-threatening infectious diarrhea in hospitalized patients accounting for 20% to 30% of all diarrhoea cases in humans. Clostridioides difficile'
Dr Ben Prinsloo, Miss Hlambani Shirinda, Prof Anthony Smith, Prof Marthie Ehlers   +3 more
doaj   +1 more source

709. Post-Clostridioides difficile Infection Neuroinflammatory Response in an Animal Model [PDF]

, 2023
Suemin E Yang, Deiziane Viana da Silva Costa, Sophia M. Goldbeck, Jae Hyun Shin, Cirle A. Warren   +4 more
openalex   +1 more source

Evaluation of three commercial rapid immunoassays for the diagnosis of Clostridioides difficile infection

Microbiology Spectrum
Current guidelines recommend the use of a two-step algorithm for the laboratory diagnosis of Clostridioides difficile infection (CDI). Several commercial rapid immunoassays that detect both GDH and toxin A/B in stool samples are available and could be ...
Hannes Bjarki Vigfússon, Theresa Ennefors, Torbjörn Norén, Martin Sundqvist   +3 more
doaj   +1 more source

Exploring the Toxin-Mediated Mechanisms in Clostridioides difficile Infection

Microorganisms
Clostridioides difficile infection (CDI) is the leading cause of nosocomial antibiotic-associated diarrhea, and colitis, with increasing incidence and healthcare costs. Its pathogenesis is primarily driven by toxins produced by the bacterium C. difficile,
Evdokia Pourliotopoulou, T. Karampatakis, Melania Kachrimanidou   +2 more
semanticscholar   +1 more source

Comparison of fidaxomicin, metronidazole and vancomycin for initial episode and recurrence of Clostridioides difficile infection - An observational cohort study

Heliyon
Objectives: The main aim of this study was to compare the clinical outcomes of patients attended in our area with Clostridioides difficile infection (CDI) (sustained cure, recurrence or death) in relation to treatment to normal or hypervirulent C ...
Marcos Hernando-Gozalo, Carlos Rescalvo-Casas, Laura Seijas-Pereda, Juan Cuadros-González, Ramón Pérez-Tanoira   +4 more
doaj   +1 more source

Understanding host immune responses in Clostridioides difficile infection: Implications for pathogenesis and immunotherapy

iMeta
Clostridioides difficile (C. difficile) is the predominant causative agent of nosocomial diarrhea worldwide. Infection with C. difficile occurs due to the secretion of large glycosylating toxin proteins, which can lead to toxic megacolon or mortality in ...
Lamei Wang, Javier A Villafuerte Gálvez, Christina Lee, Shengru Wu, Ciar n P. Kelly, Xinhua Chen, Yangchun Cao   +6 more
semanticscholar   +1 more source

2351. Rate and Consequences of Missed Clostridioides (Clostridium) difficile Infection Diagnosis from Non-disclosure of Clostridioides difficile Multiplex PCR Results. Two-Hospital Experience [PDF]

, 2019
Ioannis M. Zacharioudakis, Fainareti N. Zervou, Michael Phillips, Maria E. Aguero‐Rosenfeld   +3 more
openalex   +1 more source

Australasian Society of Infectious Diseases updated guidelines for the management of Clostridioides difficile infection in adults and children in Australia and New Zealand [PDF]

Anthony Longhitano, Christine Röder, Tim Blackmore, Anita J Campbell, Meryta May, Eugene Athan   +5 more
openalex   +1 more source

Healthcare-Associated Clostridioides difficile Infection: A Hospital-Based Retrospective Study in North Eastern Romania [PDF]

Lidia Oana Stămăteanu, Ionela-Larisa Miftode, Claudia Plesca, Mihnea Eudoxiu Hurmuzache, Doina Carmen Manciuc, Daniela Leca, Egidia Miftode   +6 more
openalex   +1 more source

Prevalence of Comorbid Factors in Patients With Recurrent Clostridioides difficile Infection in ECOSPOR III, a Randomized Trial of an Oral Microbiota–Based Therapeutic [PDF]

, 2023
Charles S. Berenson, Bret A. Lashner, Louis Y. Korman, Elizabeth Hohmann, Abhishek Deshpande, Thomas Louie, Matthew Sims, Darrell S. Pardi, Colleen S. Kraft, Elaine E. L. Wang, Stuart H. Cohen, Paul Feuerstadt, Caterina Oneto, Bharat Misra, John Pullman, Ananya De, Aslı Memişoğlu, David A. Lombardi, Brooke Hasson, Barbara McGovern, Lisa Von Moltke, Christine H. Lee   +21 more
openalex   +1 more source