Results 161 to 170 of about 54,164 (265)

SER-109 (VOWST™): A Review in the Prevention of Recurrent Clostridioides difficile Infection

Drugs
SER-109 (VOWST™; fecal microbiota spores, live-brpk) is a live biotherapeutic product indicated to prevent the recurrence of Clostridioides difficile infection (CDI) in patients 18 years of age and older following standard of care (SOC) antibacterial ...
Hannah A. Blair
semanticscholar   +1 more source

Re-establishing bile acid composition after treatment of recurrent Clostridioides difficile infection with fecal microbiota transplantation compared with oral vancomycin or a 12-strain bacterial mixture

Gut Microbes
Patients with Clostridioides difficile infection have high colonic levels of primary bile acids, which are potent germinators of Clostridioides difficile.
Anne Abildtrup Rode, Henri Duboc, Antonin Lamazière, Dominique Rainteau, Lydie Humbert, Emilie Gauliard, Mahtab Chehri, Andreas Munk Petersen, Morten Helms, Kristian Schønning, Henrik Vedel Nielsen, Peter Bytzer, Jørgen Engberg   +12 more
doaj   +1 more source

Laboratory diagnostic methods for clostridioides difficile infection

One Health & Risk Management, 2023
Introduction. Clostridioides difficile is an anaerobic gram-positive, sporeforming, toxin-producing bacillus that is transmitted among humans through the fecal-oral route, as a result of ingestion of spores. Colonization of C.
Anastasia ALEXANDROV
doaj  

Clostridioides difficile infection in hospital and community settings: summary document of a multidisciplinary group [PDF]

Clostridioides difficile infection (CDI) affects the majority of hospital wards. In the context of a Continuing Medical Education Field Training course, a multidisciplinary group of expert healthcare professionals addressed the issue of CDI, producing a ...
Danise A., Furfaro F., Gattuso G., Liberato N. L., Mandelli C., Mazzola G., Osnaghi B.   +6 more
core   +1 more source

Emerging Diagnostics in Clostridioides difficile Infection

International Journal of Molecular Sciences
Clostridioides difficile detection in community settings is time-intensive, resulting in delays in diagnosing and quarantining infected individuals. However, with the advent of semi-automated devices and improved algorithms in recent decades, the ability to discern CDI infection from asymptomatic carriage has significantly improved.
openaire   +2 more sources

\u3ci\u3eClostridioides difficile\u3c/i\u3e Infection Study Models and Prospectives for Probing the Microbe-Host Interface [PDF]

Clostridioides difficile infection (CDI) is an urgent public health threat with a high rate of recurrence and limited treatment options. In vivo models have been indispensable in understanding CDI pathophysiology and establishing treatment protocols and ...
Courson, David S., Purcell, Erin B., Zvonareva, Tatiana   +2 more
core   +1 more source

The Role of Clostridioides difficile Within the One Health Framework: A Review

Microorganisms
Clostridioides difficile is the leading cause of antibiotic-associated diarrhea in hospitalized patients. In recent years, the incidence of C. difficile infection (CDI) has increased globally, with a notable rise in community-associated CDI (CA-CDI). The
Sotiris Alexiou, Anastasia Diakou, Melania Kachrimanidou   +2 more
doaj   +1 more source

A Review of Therapies for Clostridioides difficile Infection

Antibiotics
Clostridioides difficile is an urgent public health threat that affects approximately half a million patients annually in the United States. Despite concerted efforts aimed at the prevention of Clostridioides difficile infection (CDI), it remains a ...
Faiza Morado, Neha Nanda
doaj   +1 more source

Real-world Effectiveness of Fecal Microbiota Transplantation for First or Second Clostridioides difficile Infection [PDF]

Background & Aims: Clostridioides difficile infection (CDI) is associated with high mortality. Fecal microbiota transplantation (FMT) is an established treatment for recurrent CDI, but its use for first or second CDI remains experimental. We aimed to
Baumwall, Simon Mark Dahl, Birn, Frederik Hyllested, Dahlerup, Jens Frederik, Erikstrup, Christian, Erikstrup, Lise Tornvig, Fernis, Christa Marie Culmbach, Glerup, Henning, Grosen, Anne Karmisholt, Hansen, Mette Mejlby, Helms, Morten, Hvas, Christian Lodberg, Kelsen, Jens, Krarup, Anne Lund, Lødrup, Anders Bergh, Mikkelsen, Susan, Neumann, Anders, Paaske, Sara Ellegaard, Rubak, Tone, Rågård, Nina, Svenningsen, Lise, Vinter-Jensen, Lars   +20 more
core   +2 more sources

Microbiota-Based Live Biotherapeutic Products for Clostridioides Difficile Infection- The Devil is in the Details

Infection and Drug Resistance
Clostridioides difficile infection (CDI) remains a significant contributor to healthcare costs and morbidity due to high rates of recurrence. Currently, available antibiotic treatment strategies further disrupt the fecal microbiome and do not address the
Lea M Monday, G. Tillotson, Teena Chopra
semanticscholar   +1 more source