Results 11 to 20 of about 18,494 (211)

Epidemiology of Clostridioides difficile Infection in Portugal: A Retrospective, Observational Study of Hospitalized Patients

open access: yesActa Médica Portuguesa, 2022
Introduction: Clostridioides difficile is the main cause of healthcare-associated diarrhea in Europe and North America. The aim of this study was to characterize the epidemiology and clinical burden of Clostridioides difficile infection among ...
Cláudia Nazareth   +14 more
doaj   +1 more source

Phage therapy for Clostridioides difficile infection

open access: yesFrontiers in Immunology, 2022
Clostridioides difficile is endemic in the intestinal tract of healthy people. However, it is responsible for many healthcare-associated infections, such as nosocomial diarrhea following antibiotic treatment. Importantly, there have been cases of unsuccessful treatment and relapse related to the emergence of highly virulent strains of C.
Kosuke Fujimoto   +3 more
openaire   +3 more sources

Diagnostic Methods of Clostridioides difficile Infection and Clostridioides difficile Ribotypes in Studied Sample [PDF]

open access: yesAntibiotics, 2021
Background: Clostridioides (Clostridium) difficile is the most common nosocomial pathogen and antibiotic-related diarrhea in health-care facilities. Over the last few years, there was an increase in the incidence rate of C. difficile infection cases in Slovakia.
Elena Novakova   +3 more
openaire   +3 more sources

IL-27 induces LL-37/CRAMP expression from intestinal epithelial cells: implications for immunotherapy of Clostridioides difficile infection

open access: yesGut Microbes, 2021
Clostridioides difficile infection is currently the leading cause of nosocomial antibiotic-associated diarrhea and pseudomembranous colitis worldwide. Cathelicidins, a major group of natural antimicrobial peptides, have antimicrobial and immunomodulatory
Banglao Xu, Xianan Wu, Yi Gong, Ju Cao
doaj   +1 more source

Clostridioides difficile Infection [PDF]

open access: yesAnnals of Internal Medicine, 2018
Clostridioides difficile (formerly Clostridium difficile) infection is the most frequently identified health care-associated infection in the United States. C difficile has also emerged as a cause of community-associated diarrhea, resulting in increased incidence of community-associated infection.
Alice Guh, Preeta K. Kutty
openaire   +2 more sources

An Integrated Pipeline For Prediction of Clostridioides Difficile Infection [PDF]

open access: yesScientific Reports, 2022
Abstract With the expansion of electronic health records(EHR)-linked genomic data comes the development of machine learning-enable models. There is a pressing need to develop robust pipelines to evaluate performance of integrated models and minimize systemic bias. We developed a prediction model of symptomatic Clostridioides difficile infection(
Jiang Li   +8 more
openaire   +3 more sources

Faecal transplantation and Clostridioides difficile infection [PDF]

open access: yesScripta Medica, 2021
Faecal microbiota transplantation (FMT), known equally well as faecal transplantation or faecal bacteriotherapy, is the process of implanting the faecal suspension containing balanced microbiota from a healthy donor to the colon of a recipient patient.
A Darija Knežević, Miroslav Petković
openaire   +2 more sources

Does Fecal Microbiota Transplant Have a Role in Treating Recurrent Clostridioides difficile Infection in Rural Hospitals?

open access: yesFrontiers in Public Health, 2021
Clostridioides difficile infection possesses a significant economical burden, specifically in the inpatient and rural settings. Fecal Microbiota Transplant has been used for treatment of recurrent Clostridioides difficile but its utility is limited by ...
Krishna Vedala   +3 more
doaj   +1 more source

Costs Associated with the Treatment of Clostridioides Difficile Infections [PDF]

open access: yesInternational Journal of Environmental Research and Public Health, 2021
Background: Clostridioides difficile, as the main cause of infectious diarrhoea in hospitalised patients, is a considerable challenge for medical personnel (hospital environment) who have direct contact with the patient, as well as being of interest to public health specialists.
Aleksandra Sierocka   +3 more
openaire   +3 more sources

Management of Clostridioides difficile Infection [PDF]

open access: yesCritical Care Nurse, 2019
Clostridioides (formerly Clostridium) difficile infection is among the most identified causes of health care-associated infections in US hospitals and remains a major public health problem. The incidence and severity of C difficile infection are high among critically ill patients.
Stephanie Quist   +4 more
openaire   +3 more sources

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