Results 31 to 40 of about 44,840 (262)

Hospital Infection Control: Clostridioides difficile

Clinics in Colon and Rectal Surgery, 2020
Abstract Clostridioides difficile remains a leading cause of healthcare-associated infection. Efforts at C. difficile prevention have been hampered by an increasingly complex understanding of transmission patterns and a high degree of heterogeneity among existing studies. Effective prevention of C.
Turner, Nicholas A, Anderson, Deverick J
openaire   +3 more sources

Comparison of Different Antibiotics and the Risk for Community-Associated Clostridioides difficile Infection: A Case–Control Study

Open Forum Infectious Diseases, 2023
Background Antibiotics are the greatest risk factor for Clostridioides difficile infection (CDI). Risk for CDI varies across antibiotic types and classes. Optimal prescribing and stewardship recommendations require comparisons of risk across antibiotics.
A. Miller, A. Arakkal, Daniel K. Sewell, Alberto Maria Segre, Joseph Tholany, P. Polgreen   +5 more
semanticscholar   +1 more source

In Vitro Activity of Omadacycline and Five Comparators against Contemporary Ribotypes of Clostridioides difficile in Stockholm, Sweden

Microbiology Spectrum, 2021
Clostridioides difficile infection represents a growing clinical challenge. The new compound omadacycline is a potential treatment alternative, as many antibiotics have limited activity or are rarely used due to costs and side effects.
Angela Camporeale, Chaitanya Tellapragada, Jelena Kornijenko, Carl Erik Nord, Christian G. Giske   +4 more
doaj   +1 more source

Gut microbiota changes associated with Clostridioides difficile infection and its various treatment strategies

Gut microbes, 2023
Human gut microbiota are critical to both the development of and recovery from Clostridioides difficile infection (CDI). Antibiotics are the mainstay of CDI treatment, yet inherently cause further imbalances in the gut microbiota, termed dysbiosis ...
A. Gonzales-Luna, T. Carlson, K. Garey
semanticscholar   +1 more source

Clostridioides (Clostridium) difficile Pacemaker Infection [PDF]

Open Forum Infectious Diseases, 2020
Abstract Clostridioides difficile is the leading cause of antibiotic-associated nosocomial diarrhea, but extra-intestinal manifestations are rare. We describe the first documented case of bacteraemia with pacemaker pocket and lead infection with the toxigenic C. difficile ribotype 014 with a lack of abdominal symptoms.
Anna Berkefeld, Fabian K Berger, Barbara C Gärtner, Nina Wantia, Anatol Prinzing, Karl-Ludwig Laugwitz, Dirk H Busch, Kathrin Rothe   +7 more
openaire   +3 more sources

Enterotoxic Clostridia:Clostridioides difficileInfections [PDF]

Microbiology Spectrum, 2019
ABSTRACTClostridioides difficileis a Gram-positive, anaerobic, spore forming pathogen of both humans and animals and is the most common identifiable infectious agent of nosocomial antibiotic-associated diarrhea. Infection can occur following the ingestion and germination of spores, often concurrently with a disruption to the gastrointestinal microbiota,
S, Mileto, A, Das, D, Lyras
openaire   +2 more sources

Phage therapy for Clostridioides difficile infection

Frontiers in Immunology, 2022
Clostridioides difficile is endemic in the intestinal tract of healthy people. However, it is responsible for many healthcare-associated infections, such as nosocomial diarrhea following antibiotic treatment. Importantly, there have been cases of unsuccessful treatment and relapse related to the emergence of highly virulent strains of C.
Kosuke Fujimoto, Kosuke Fujimoto, Satoshi Uematsu, Satoshi Uematsu   +3 more
openaire   +3 more sources

Safety of fecal microbiota, live-jslm (REBYOTA™) in individuals with recurrent Clostridioides difficile infection: data from five prospective clinical trials

Therapeutic Advances in Gastroenterology, 2023
Background: Microbiota-based treatments reduce the incidence of recurrent Clostridioides difficile infections (rCDIs), but prospectively collected safety data needed to broaden patient access and protect public health have been limited.
Christine Lee, T. Louie, Lindy L. Bancke, B. Guthmueller, Adam J Harvey, P. Feuerstadt, S. Khanna, R. Orenstein, E. Dubberke   +8 more
semanticscholar   +1 more source

Fecal Microbiota Transplantation beyond Clostridioides Difficile Infection [PDF]

Clinical Endoscopy, 2021
With advancing analytical methods for gut microbes, many studies have been conducted, revealing that gut microbes cause various diseases, including gastrointestinal and non-gastrointestinal diseases. Accordingly, studies have been actively conducted to analyze the effects on the prevention and treatment of these diseases through changes in intestinal ...
Chang Mo Moon, Sung Noh Hong
openaire   +3 more sources

Emerging applications of phage therapy and fecal virome transplantation for treatment of Clostridioides difficile infection: challenges and perspectives

Gut Pathogens, 2023
Clostridioides difficile , which causes life-threatening diarrheal disease, is considered an urgent threat to healthcare setting worldwide. The current standards of care solely rely on conventional antibiotic treatment, however, there is a risk of ...
H. Raeisi, M. Noori, M. Azimirad, S. Mohebbi, H. Asadzadeh Aghdaei, Abbas Yadegar, M. Zali   +6 more
semanticscholar   +1 more source