Results 31 to 40 of about 19,142 (210)

Prevention of Clostridioides difficile in hospitals: A position paper of the International Society for Infectious Diseases

International Journal of Infectious Diseases, 2021
Clostridioides difficile infection is an increasing presence worldwide. Prevention is multipronged, reflecting a complex and evolving epidemiology. Multiple guidelines exist regarding the prevention of C.
Michelle Doll, Alexandre R. Marra, Anucha Apisarnthanarak, Amal Saif Al-Maani, Salma Abbas, Victor D. Rosenthal   +5 more
doaj   +1 more source

Role of diagnostic stewardship in reducing healthcare-facility–onset Clostridioides difficile infections

Antimicrobial Stewardship & Healthcare Epidemiology, 2023
We describe the implementation of an electronic medical record “hard stop” to decrease inappropriate Clostridioides difficile testing across a 5-hospital health system, effectively reducing the rates of healthcare-facility–onset C.
Anita B. Shallal, Medha Cherabuddi, Lance Podsiad, Christopher Gortat, Clare Shanahan, Tarlisha Holsey, Linoj Samuel, George Alangaden, Geehan Suleyman   +8 more
doaj   +1 more source

Clostridioides difficile infection

Infectious Disease Clinics of North America
Mada PK, Alam MU.
europepmc   +4 more sources

The Bacterial Gut Microbiota of Adult Patients Infected, Colonized or Noncolonized by Clostridioides difficile

Microorganisms, 2020
Gut microbiota composition in patients with Clostridioides difficile colonization is not well investigated. We aimed to identify bacterial signatures associated with resistance and susceptibility to C.
Monique J. T. Crobach, Quinten R. Ducarmon, Elisabeth M. Terveer, Celine Harmanus, Ingrid M. J. G. Sanders, Kees M. Verduin, Ed J. Kuijper, Romy D. Zwittink   +7 more
doaj   +1 more source

Reduction in Health Care Facility–Onset Clostridioides difficile Infection: A Quality Improvement Initiative

Mayo Clinic Proceedings: Innovations, Quality & Outcomes, 2021
Objective: To reduce health care facility–onset (HCFO) Clostridioides difficile infection (CDI) incidence by improving diagnostic stewardship and reducing the inappropriate testing of C difficile assays.
Himesh B. Zaver, MD, Varun P. Moktan, MD, Eugene P. Harper, MD, Aman Bali, MD, Ayan Nasir, MD, Carla Foulks, MD, Justin Kuhlman, MD, Max Green, MD, Gillian A. Algan, BS, Heather C. Parth, MPH, Melody Wu-Ballis, BS, Sandra DiCicco, BS, Brenda T. Smith, BS, Ronald N. Owen, BS, Lorraine S. Mai, BS, Sarah L. Spiros, BS, John Griffis, BS, Daphne T. Ramsey Walker, BS, D. Jane Hata, PhD, Justin M. Oring, DO, Harry R. Powers, MD, Wendelyn Bosch, MD   +21 more
doaj   +1 more source

Costs Associated with the Treatment of Clostridioides Difficile Infections [PDF]

International Journal of Environmental Research and Public Health, 2021
Background: Clostridioides difficile, as the main cause of infectious diarrhoea in hospitalised patients, is a considerable challenge for medical personnel (hospital environment) who have direct contact with the patient, as well as being of interest to public health specialists.
Aleksandra Sierocka, Zofia Kiersnowska, Ewelina Lemiech-Mirowska, Michał Marczak   +3 more
openaire   +2 more sources

Clostridioides difficile co-infection with Enterohemorrhagic Escherichia coli (EHEC)—a potentially fatal combination

IDCases, 2020
There has been a significant increase in hospital and community acquired Clostridioides difficile infection in the past decade. In addition to CDI, the rate of infection with enterohemorrhagic Escherichia coli (EHEC) has also increased by 28% in United ...
Farah Deshmukh, Upasana Agrawal, Nancy Merrell   +2 more
doaj   +1 more source

My Treatment Approach to Clostridioides difficile Infection [PDF]

Mayo Clinic Proceedings, 2021
Clostridioides difficile infection is the most common cause of infectious diarrhea in hospitals with an increasing incidence in the community. Clinical presentation of C difficile infection ranges from diarrhea manageable in the outpatient setting to fulminant infection requiring intensive care admission.
openaire   +2 more sources

Clostridioides difficile Infection: A Room for Multifaceted Interventions [PDF]

Journal of Clinical Medicine, 2020
Clostridioides difficile (CD) continues to be the number one health care-associated infectious pathogen in the United States [...]
Nicola Petrosillo, Maria Adriana Cataldo
openaire   +2 more sources

Development of Peptide Glucosyltransferase Inhibitors With Comprehensive Coverage Across Clostridioides difficile Toxin B Sub‐Types

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Clostridioides difficile infection presents an escalating clinical challenge due to the proliferation of hypervirulent and antibiotic‐resistant strains. The primary symptoms of disease, namely colitis and diarrhea, are induced by the release of two toxins: TcdA and TcdB.
Carly M. Catella, Sudeep Sarma, Caroline M. Hinesley, Corey E. Febo, Keith A. Breau, Deniz Durmusoglu, Ethan Purnell, Scott T. Magness, Carol K. Hall, Stefano Menegatti, Nathan Crook   +10 more
wiley   +1 more source