Results 41 to 50 of about 44,840 (262)

Protection from Lethal Clostridioides difficile Infection via Intraspecies Competition for Cogerminant

mBio, 2021
Antibiotic-associated colitis is often caused by infection with the bacterium Clostridioides difficileC ...
Jhansi L. Leslie, Matthew L. Jenior, Kimberly C. Vendrov, Alexandra K. Standke, Madeline R. Barron, Tricia J. O’Brien, Lavinia Unverdorben, Pariyamon Thaprawat, Ingrid L. Bergin, Patrick D. Schloss, Vincent B. Young   +10 more
doaj   +1 more source

Interleukin-22-mediated host glycosylation prevents Clostridioides difficile infection by modulating the metabolic activity of the gut microbiota

Nature Medicine, 2020
The involvement of host immunity in the gut microbiota-mediated colonization resistance to Clostridioides difficile infection (CDI) is incompletely understood.
Hiroko Nagao-Kitamoto, Jhansi L. Leslie, Sho Kitamoto, C. Jin, K. Thomsson, Merritt G. Gillilland, Peter Kuffa, Y. Goto, R. Jenq, Chiharu Ishii, A. Hirayama, Anna M. Seekatz, E. Martens, K. Eaton, J. Kao, S. Fukuda, P. Higgins, N. Karlsson, V. Young, N. Kamada   +19 more
semanticscholar   +1 more source

Clostridioides difficile Infection

RGUHS Journal of Medical Sciences, 2022
In the past decade Clostrdioides difficile has become a leading enteric pathogen causing antibiotic-associated diarrohoea and colitis. The manifestations range from diarrhoea to life-threatening damage to the large intestine. It is noted as a nosocomial and community acquired infection in most of the countries including India.
openaire   +1 more source

Outbreak of Clostridioides difficile infection in Silesian district hospital

Annales Academiae Medicae Silesiensis, 2023
INTRODUCTION: In order to evaluate a Clostridioides difficile infection (CDI) outbreak between December 2018 and February 2019 in the internal medicine ward of a district hospital in Silesia, 6 stools from 5 patients were examined.
Klaudia T. Szarek, Monika A. Kabała, Krzysztof Sacha, Franciszek Drzymała, Adam Borek, Monika Pomorska-Wesołowska, Małgorzata Aptekorz, Gayane Martirosian   +7 more
doaj   +1 more source

Effective Dosage of Oral Vancomycin in Treatment for Initial Episode of Clostridioides difficile Infection: A Systematic Review and Meta-Analysis

Antibiotics, 2019
Background: Oral vancomycin is a first line treatment for an initial episode of Clostridioides difficile infection. However, the comparative efficacy of different dosing regimens is lacking evidence in the current literature. Methods: We searched PubMed,
Chia-Yu Chiu, Amara Sarwal, Addi Feinstein, Karen Hennessey   +3 more
doaj   +1 more source

Freeze-dried fecal samples are biologically active after long-lasting storage and suited to fecal microbiota transplantation in a preclinical murine model of Clostridioides difficile infection

Gut Microbes, 2020
Fecal microbiota transplantation is now recommended for treating recurrent forms of Clostridioides difficile infection. Recent studies have reported protocols using capsules of either frozen or freeze-dried stool allowing oral administration in in- and ...
Julie Reygner, Christine Charrueau, Johanne Delannoy, Camille Mayeur, Véronique Robert, Céline Cuinat, Thierry Meylheuc, Aurélie Mauras, Jérémy Augustin, Ioannis Nicolis, Morgane Modoux, Francisca Joly, Anne-Judith Waligora-Dupriet, Muriel Thomas, Nathalie Kapel   +14 more
doaj   +1 more source

Prevention of Clostridioides difficile in hospitals: A position paper of the International Society for Infectious Diseases

International Journal of Infectious Diseases, 2021
Clostridioides difficile infection is an increasing presence worldwide. Prevention is multipronged, reflecting a complex and evolving epidemiology. Multiple guidelines exist regarding the prevention of C.
Michelle Doll, Alexandre R. Marra, Anucha Apisarnthanarak, Amal Saif Al-Maani, Salma Abbas, Victor D. Rosenthal   +5 more
doaj   +1 more source

Emerging Options for the Prevention and Management of Clostridioides difficile Infection

Drugs, 2023
Agents in development for the prevention or treatment of Clostridioides difficile infection can be split into three broad categories: antibiotics, microbiome restoration, and vaccines.
A. Gonzales-Luna, T. Carlson, K. Garey
semanticscholar   +1 more source

Role of diagnostic stewardship in reducing healthcare-facility–onset Clostridioides difficile infections

Antimicrobial Stewardship & Healthcare Epidemiology, 2023
We describe the implementation of an electronic medical record “hard stop” to decrease inappropriate Clostridioides difficile testing across a 5-hospital health system, effectively reducing the rates of healthcare-facility–onset C.
Anita B. Shallal, Medha Cherabuddi, Lance Podsiad, Christopher Gortat, Clare Shanahan, Tarlisha Holsey, Linoj Samuel, George Alangaden, Geehan Suleyman   +8 more
doaj   +1 more source

The Environment, Farm Animals and Foods as Sources of Clostridioides difficile Infection in Humans

Foods, 2023
The recent discovery of the same Clostridioides difficile ribotypes associated with human infection in a broad range of environments, animals and foods, coupled with an ever-increasing rate of community-acquired infections, suggests this pathogen may be ...
D. Bolton, P. Marcos
semanticscholar   +1 more source