Results 51 to 60 of about 18,494 (211)

Infant Acid‐Suppressant Medication, C. difficile Colonisation, and Childhood Body Mass Index in a Canadian Cohort

Acta Paediatrica, EarlyView.
ABSTRACT Aim To determine relationships between paediatric use of acid‐suppressive medications (ASMs) (proton pump inhibitors (PPI) and histamine‐2 receptor antagonists (H2RA)) and preschool body mass index (BMI) and mediation by C. difficile colonisation. Methods ASMs were parent‐reported at age 3, 6 and 12 months in 1025 infants from the CHILD Cohort
Sarah L. Bridgman, Kelsea M. Drall, Amanda A. Lau, Hein M. Tun, Nadia P. Morales‐Lizcano, Hien Q. Huynh, Piushkumar J. Mandhane, Theo J. Moraes, Elinor Simons, Stuart E. Turvey, Padmaja Subbarao, James A. Scott, Anita L. Kozyrskyj   +12 more
wiley   +1 more source

The analysis of the epidemic status and risk factors associated with different genotypes Clostridioides difficile mixed infection

BMC Microbiology
Background Clostridioides difficile is the main pathogen of antibiotic-associated diarrhea and pseudomembranous enteritis. Mixed Clostridioides difficile infection are simultaneous infection of the same host with strains of different genotypes. In recent
Yulian Zhang, Jing Yang, Honglian Wei, Jie Wang, Pu Qin, Qianqing Li, Cuixin Qiang, Jianhong Zhao   +7 more
doaj   +1 more source

The cytotoxic synergy between Clostridioides difficile toxin B and proinflammatory cytokines: an unholy alliance favoring the onset of Clostridioides difficile infection and relapses

MicrobiologyOpen, 2020
Clostridioides difficile infection (CDI) represents an important health problem worldwide, with significant morbidity and mortality. This infection has also high recurrence rates, whose pathophysiological grounds are still poorly understood. Based on our
Gabrio Bassotti, Andrea Marchegiani, Pierfrancesco Marconi, Katia Fettucciari   +3 more
doaj   +1 more source

Improving Clinical Outcomes of Encapsulated Faecal Microbiota Transplantation for Clostridioides difficile Infection Through Empirical Donor Selection and Optimised Dosing: A Quality Improvement Study

Alimentary Pharmacology &Therapeutics, EarlyView.
In a large‐scale, multiple‐site Danish faecal microbiota transplantation (FMT) system, the cure rates in patients with Clostridioides difficile infection treated with encapsulated FMT were improved following exclusion of three low‐performing donors and implementation of a two‐dose FMT regimen.
Sara Ellegaard Paaske, Simon Mark Dahl Baunwall, Tone Rubak, Nina Rågård, Jens Kelsen, Mette Mejlby Hansen, Anders Bergh Lødrup, Søren Lyhne, Emilie Glavind, Christa Marie Culmback Fernis, Stine Hald, Lise Tornvig Erikstrup, Lars Vinter‐Jensen, Simon Lal, Susan Mikkelsen, Christian Erikstrup, Jens Frederik Dahlerup, Christian Lodberg Hvas   +17 more
wiley   +1 more source

Genomic characterization of nine Clostridioides difficile strains isolated from Korean patients with Clostridioides difficile infection

Gut Pathogens, 2021
Background Clostridioides difficile infection (CDI) is an infectious nosocomial disease caused by Clostridioides difficile, an opportunistic pathogen that occurs in the intestine after extensive antibiotic regimens. Results Nine C.
Seung Woo Ahn, Se Hee Lee, Uh Jin Kim, Hee-Chang Jang, Hak-Jong Choi, Hyon E. Choy, Seung Ji Kang, Seong Woon Roh   +7 more
doaj   +1 more source

Antimicrobial prescribing guidelines for horses in Australia

Australian Veterinary Journal, EarlyView.
The growing problem of antimicrobial resistance also affects equine veterinarians with increasing frequency. Antimicrobial stewardship and responsible prescribing are essential for a future in which effective antimicrobials are available, as it is unlikely that new antimicrobials will become available for use in horses.
L Hardefeldt, K Thomas, S Page, J Norris, G Browning, C El Hage, A Stewart, J Gilkerson, G Muscatello, D Verwilghen, G van Galen, J Bauquier, R Cuming, B Reynolds, C Whittaker, E Wilkes, J Clulow, C Burden, L Begg   +18 more
wiley   +1 more source

Fecal microbiota transplantation in a patient hospitalized in the intensive care unit – Case report

Heliyon
Clostridioides difficile infections are difficult and serious problem occurring in patients staying in intensive care units. In recent years, the number and severity of these infections, as well as the mortality rate, have been increasing, posing a ...
Katarzyna Oliwa-Libumska, Aleksandra Jaworska-Czerwinska, Malgorzata Mallek-Grabowska, Robert Wlodarski, Przemyslaw Zuratynski, Bartosz Kozlowski   +5 more
doaj   +1 more source

Clostridioides difficile infection in the Asia-Pacific region [PDF]

Emerging Microbes & Infections, 2019
Clostridioides difficile causes healthcare-related diarrhoea in high-income countries. Highly resistant spores persist in healthcare facilities, primarily infecting patients who have recently received antimicrobials. C. difficile infection (CDI) has been studied in detail in North America and Europe; however, the epidemiology of CDI elsewhere ...
Deirdre A. Collins, Kyung Mok Sohn, Yuan Wu, Kentaro Ouchi, Yoshikazu Ishii, Briony Elliott, Thomas V. Riley, Kazuhiro Tateda   +7 more
openaire   +4 more sources

Microbial and Metabolic Disorders in Cervical Cancer: Structural Insights, Biomarkers, Mechanisms, and Therapeutic Strategies

Cancer Science, EarlyView.
We unravel synergistic mechanisms by which microbial‐host metabolic networks regulate the tumor immune microenvironment and therapy resistance, bridging gaps between microbiota research and cancer metabolism. Identified biomarkers (e.g., Lactobacillus, C8‐ceramide‐1‐phosphate) and therapeutic approaches (e.g., FMT combined with immune checkpoint ...
Hong Tao, Luyu Wang, Yi Ding, Lixian Yi, Mutian Han, Mengmeng Gu, Jian Wu   +6 more
wiley   +1 more source

Risks and Preventive Strategies for Clostridioides difficile Transmission to Household or Community Contacts during Transition in Healthcare Settings

Emerging Infectious Diseases, 2021
The burden of Clostridioides difficile infection (CDI) has greatly increased. We evaluated the risks for CDI transmission to community members after hospitalized patients are discharged.
Ramin Asgary, Jessica A. Snead, Nabeel A. Wahid, Vicky Ro, Marina Halim, Judy C. Stribling   +5 more
doaj   +1 more source