Results 81 to 90 of about 44,840 (262)

A Systematic Literature Review on Risk Factors for and Timing of Clostridioides difficile Infection in the United States

Infectious Disease and Therapy
Clostridioides difficile infection (CDI) is a major public health threat. Up to 40% of patients with CDI experience recurrent CDI (rCDI), which is associated with increased morbidity.
Jennifer Eeuwijk, Gui Ferreira, J. Yarzábal, Mirna Robert-Du Ry van Beest Holle   +3 more
semanticscholar   +1 more source

A novel kirkovirus may be associated with equine gastrointestinal disease

Equine Veterinary Journal, EarlyView.
Abstract Background Many cases of equine enterocolitis are suspected to be infectious in nature, but no pathogen is identified in many cases. Objectives Perform next‐generation sequencing on faeces collected from cases of equine enterocolitis for the presence of novel viruses and determine if an identified novel virus is associated with cases of equine
Lillian M. B. Haywood, Ava Clark, Ben Hause, Breanna Sheahan   +3 more
wiley   +1 more source

Microbial bile salt hydrolases mediate the efficacy of faecal microbiota transplant in the treatment of recurrent Clostridioides difficile infection

Gut, 2019
Objective Faecal microbiota transplant (FMT) effectively treats recurrent Clostridioides difficile infection (rCDI), but its mechanisms of action remain poorly defined. Certain bile acids affect C. difficile germination or vegetative growth.
B. Mullish, J. McDonald, A. Pechlivanis, J. Allegretti, D. Kao, Grace F. Barker, D. Kapila, E. Petrof, S. Joyce, C. Gahan, Izabela Glegola-Madejska, H. Williams, E. Holmes, Thomas B. Clarke, M. Thursz, J. Marchesi   +15 more
semanticscholar   +1 more source

Bacterial Extracellular Vesicles in the Pathogenesis and Treatment of Liver Diseases

Journal of Gastroenterology and Hepatology, EarlyView.
Liver diseases are a major global health challenge, with current treatments inadequate. This review highlights the role of bacterial extracellular vesicles in liver inflammation, fibrosis, and metabolism. We also explore these from commensals and probiotics, their protective effects, and discuss research challenges and future therapeutic potential ...
Yakun Li, Jia Li, Robin P. F. Dullaart, Han Moshage   +3 more
wiley   +1 more source

Risks and Preventive Strategies for Clostridioides difficile Transmission to Household or Community Contacts during Transition in Healthcare Settings

Emerging Infectious Diseases, 2021
The burden of Clostridioides difficile infection (CDI) has greatly increased. We evaluated the risks for CDI transmission to community members after hospitalized patients are discharged.
Ramin Asgary, Jessica A. Snead, Nabeel A. Wahid, Vicky Ro, Marina Halim, Judy C. Stribling   +5 more
doaj   +1 more source

Bile acid-independent protection against Clostridioides difficile infection

PLoS Pathogens, 2021
Clostridioides difficile infections occur upon ecological / metabolic disruptions to the normal colonic microbiota, commonly due to broad-spectrum antibiotic use.
A. M. Aguirre, Nazlı Yalçınkaya, Qinglong Wu, A. Swennes, M. Tessier, P. Roberts, F. Miyajima, T. Savidge, Joseph A. Sorg   +8 more
semanticscholar   +1 more source

Treatment ofClostridioides (Clostridium) difficileinfection

Annals of Medicine, 2019
Clostridioides (formerly: Clostridium) difficile infection (CDI) is a major cause of diarrhoea for inpatients as well as outpatients. Usually, CDI is healthcare-associated but the number of community-acquired infections is increasing. CDI is generally associated with changes in the normal intestinal microbiota caused by administration of antibiotics ...
Oksi Jarmo, Anttila Veli-Jukka, Mattila Eero   +2 more
openaire   +4 more sources

Microbe–microbe interactions during Clostridioides difficile infection

Current Opinion in Microbiology, 2020
Clostridioides difficile is the leading cause of hospital-acquired gastrointestinal infections and a major public health burden in the United States. C. difficile infection causes a spectrum of disease from mild diarrhea to severe complications such as pseudomembranous colitis, toxic megacolon and death.
Arwa Abbas, Joseph P Zackular
openaire   +3 more sources

Stewardship of Molecular Diagnostics in Transplant Viral Infections

Transplant Infectious Disease, EarlyView.
ABSTRACT The transplant environment requires special considerations when testing for viral infections as immunosuppression results in atypical infection profiles. Microbes otherwise considered commensals or causing mild disease can lead to severe infections in transplant environments. Therefore, guidelines tend to recommend broader microbial testing in
Scott Sugden, David Reynoso, Reema Mathew, Michael Loeffelholz   +3 more
wiley   +1 more source

Edoxaban‐induced enterocolitis: The first case report demonstrating distinct endoscopic and histological features

DEN Open, Volume 6, Issue 1, April 2026.
Abstract Direct oral anticoagulants (DOACs), including edoxaban, are widely used for stroke prevention in atrial fibrillation and venous thromboembolism. While gastrointestinal bleeding and diarrhea are recognized adverse effects, DOAC‐induced enterocolitis has not been established as a distinct clinical entity.
Katsuya Endo, Jun Yamada, Tomofumi Katayama, Yuki Yoshino, Daisuke Fukushi, Akinobu Koiwai, Takayuki Kogure, Morihisa Hirota, Kennichi Satoh   +8 more
wiley   +1 more source