Results 41 to 50 of about 362,624 (297)

Farm level survey of spore‐forming bacteria on four dairy farms in the Waikato region of New Zealand

MicrobiologyOpen, 2017
The aim of our study was to determine the occurrence and diversity of economically important spore‐forming bacteria in New Zealand dairy farm systems.
Tanushree B. Gupta, Gale Brightwell
doaj   +1 more source

High sporulation and overexpression of virulence factors in biofilms and reduced susceptibility to vancomycin and linezolid in recurrent Clostridium [Clostridioides] difficile infection isolates [PDF]

, 2019
Clostridium [Clostridioides] difficile infection (CDI) is one of the leading causes of diarrhea associated with medical care worldwide, and up to 60% of patients with CDI can develop a recurrent infection (R-CDI). A multi-species microbiota biofilm model
Baines, Simon, Camacho-Ortiz, Adrian, Flores-Trevino, Samantha, Garza-Gonzalez, Elvira, Maldonado-Garza, Hector Jesus, Morfin-Otero, Rayo, Rodriguez-Noriega, Eduardo, Rodrıguez-Noriega, Eduardo, Tijerina-Rodrıguez, Laura, Villarreal-Trevino, Licet   +9 more
core   +2 more sources

Impact of a Diagnosis-Centered Antibiotic Stewardship on Incident Clostridioides difficile Infections in Older Inpatients: An Observational Study

Antibiotics, 2020
In 2015, a major increase in incident hospital-onset Clostridioides difficile infections (HO-CDI) in a geriatric university hospital led to the implementation of a diagnosis-centered antibiotic stewardship program (ASP).
Alain Putot, Karine Astruc, Jeremy Barben, Anca Maria Mihai, Valentine Nuss, Julien Bador, Sophie Putot, Mélanie Dipanda, Caroline Laborde, Jeremie Vovelle, Sofia Da Silva, Emmanuel Mazen, Ludwig Serge Aho Glélé, Patrick Manckoundia   +13 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Emerging trends in 'smart probiotics' : functional consideration for the development of novel health and industrial applications [PDF]

, 2017
The link between gut microbiota and human health is well-recognized and described. This ultimate impact on the host has contributed to explain the mutual dependence between humans and their gut bacteria.
El Hage, Racha, Hernandez Sanabria, Emma, Van de Wiele, Tom   +2 more
core   +3 more sources

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Clostridium sordelli causing malignant edema in a trauma patient: a case report and review of literature

The Pan African Medical Journal, 2018
Clostridium sordelli infection is a rare but potentially lethal infection associated with abortions, injury, contaminated wounds, and illicit drug use. It causes a recognizable syndrome with marked leukocytosis.
Sanjiv Fitz-Morris Gray, Beatrice Esther Dieudonne   +1 more
doaj   +1 more source

Lauric acid is an inhibitor of Clostridium difficile growth in vitro and reduces inflammation in a mouse infection model [PDF]

, 2018
Indexación: Scopus.Clostridium difficile is a Gram-positive, spore-forming anaerobic human gastrointestinal pathogen. C. difficile infection (CDI) is a major health concern worldwide, with symptoms ranging from diarrhea to pseudomembranous colitis, toxic
Ababouch, Abt, Ananthakrishnan, Barbour, Bartolotta, Bergsson, Bhattacharjee, Buckley, Burke, Carpo, Chen, Clark, Croasdell, Crowther, Dapa, Dapa, Dayrit, de Roos, Deakin, Deng, Desai, Edwards, Ekanayaka, Eyres, Ferreyra, Fischer, Francis, Galbraith, German, Harnvoravongchai, Hinton, Huang, Hung, Hung, Immanuel, Johnson, Kabara, Katan, Kim, Kint, Kitahara, Kliewer, Liu, Louie, Lynch, Martin, Martin, May, McDonald, McEllistrem, Miller, Nakatsuji, Namkung, Nobmann, Pettit, Pizarro-Guajardo, Pruitt, Rodriguez-Palacios, Rouse, Ruhr, Ruzin, Shearer, Shilling, Smits, Sorg, Surawicz, Theinsathid, Thompson, Vardakas, Villafuerte Galvez, Wilcox, Yonezawa   +71 more
core   +1 more source

Design and Synthesis of Peptide‐Polyester Conjugates for Cell‐Mediated Scaffold Degradation

Advanced Healthcare Materials, EarlyView.
This work describes polycaprolactone (PCL)‐based biomaterials engineered to degrade in response to cell‐secreted proteases. A fast‐degrading peptide (Fast) sequence is integrated into a PCL conjugate backbone to produce a biomaterial that is selectively degraded by multiple cell types compared to its scrambled control (ScrFast).
Korina Vida G. Sinad, Natasha K. Hunt, Srujan Singh, Kelly B. Seims, Yingjie Wu, E. Thomas Pashuck, Warren L. Grayson, Lesley W. Chow   +7 more
wiley   +1 more source

Prevalence and pathogenicity of binary toxin–positive Clostridium difficile strains that do not produce toxins A and B

New Microbes and New Infections, 2015
Clostridium difficile causes antibiotic-associated diarrhoea and pseudomembranous colitis. The main virulence factors of C. difficile are the toxins A (TcdA) and B (TcdB). A third toxin, called binary toxin (CDT), can be detected in 17% to 23% of strains,
C. Eckert, A. Emirian, A. Le Monnier, L. Cathala, H. De Montclos, J. Goret, P. Berger, A. Petit, A. De Chevigny, H. Jean-Pierre, B. Nebbad, S. Camiade, R. Meckenstock, V. Lalande, H. Marchandin, F. Barbut   +15 more
doaj   +1 more source