Results 61 to 70 of about 253,202 (292)

Disrupting Helicobacter pylori Iron Homeostasis With Bismuth Nanodrug‐Mediated Nutritional Trap for Targeted Gastric Infection Therapy

Advanced Science, EarlyView.
A “nutritional trap” strategy centered on disrupting bacterial iron homeostasis is proposed. The synthesized Bi‐TP@FU (TBF) can target Helicobacter pylori, interfere with the bacterial iron uptake and utilization processes to disrupt its iron homeostasis, induce bacterial death, and meanwhile preserve the balance of the intestinal flora.
Tianye Fang, Jinzhe Tong, Feng Feng, Cong Liu, Chang Shu, Jiaying Zhu, Shibo Zhang, Shuyue Deng, Wanchao Zuo, Yuhan Song, Jun Yang, Yanmin Ju, Yingying Xing, Jianjun Dai   +13 more
wiley   +1 more source

Taxonogenomic description of four new Clostridium species isolated from human gut: ‘Clostridium amazonitimonense’ , ‘Clostridium merdae’ , ‘Clostridium massilidielmoense’ and ‘Clostridium nigeriense’

New Microbes and New Infections, 2018
Culturomics investigates microbial diversity of the human microbiome by combining diversified culture conditions, matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and 16S rRNA gene identification. The present study allowed identification of four putative new Clostridium sensu stricto species: 'Clostridium amazonitimonense ...
Alou, M. T., Ndongo, S., Fregere, L., Labas, N., Andrieu, C., Richez, M., Couderc, C., Baudoin, J.-P., Abrahao, J., Brah, S., Diallo, A., Sokhna, C., Cassir, N., La Scola, B., Cadoret, F., Raoult, Didier   +15 more
openaire   +5 more sources

Gut Microbial Release of Ferulic Acid From Germinated Quinoa Alleviates Obesity‐Associated Cognitive Impairment by Activating Hippocampal Mitophagy Associated with PINK1/Parkin Pathway

Advanced Science, EarlyView.
Liberation of ferulic acid by gut microbial feruloyl esterase mediates cognitive enhancement of germinated quinoa (GQF) on obese mice. Ferulic acid enriched in GQF is released by gut microbes Roseburia hominis and R. intestinalis and subsequently mediates the neuroprotective effects of GQF on obesity‐induced cognitive decline by activating hippocampal ...
Yongli Lan, Wengang Zhang, Lei Wang, Shiyang Zhao, Yujie Song, Xinze Wang, Yutang Wang, Xijuan Yang, Shaobo Ma, Junlin Ge, Rui Guo, Xuebo Liu   +11 more
wiley   +1 more source

Clostridium beijerinckii cells expressing Neocallimastix patriciarum glycoside hydrolases show enhanced Lichenan utilization and solvent production [PDF]

, 2001
Growth and the production of acetone, butanol, and ethanol by Clostridium beijerinckii NCIMB 8052 on several polysaccharides and sugars were analyzed.
Vos, W.M., de, Mooibroek, H., Lopez-Contreras, A., van der Oost, J., Oost, J., van der, de Vos, W.M., Claassen, P.   +6 more
core  

Programmable Encapsulation Enables On‐Demand Proliferation of Therapeutic Bacteria for Potent Cancer Immunotherapy

Advanced Science, EarlyView.
A programmable encapsulation technology is developed to reduce bacterial immunogenicity and proliferation after systemic administration. The cross‐linked polymer networks around individual bacteria enable immunogenic shielding and permit selective proliferation in tumors, allowing the bacteria to convert tumor‐accumulated ammonia into L‐arginine and ...
Jianhui Yang, Ao Peng, Shuaiqiang Li, Yaning Huang, Jian Yan, Leyuan Wang, Zhihui Zhu, Fei‐Long Liu, Erbao Bian, Yang Liu, Dasheng Tian, Fenghe Li, Qi Liu   +12 more
wiley   +1 more source

Aerial dissemination of Clostridium difficile spores [PDF]

, 2008
YesClostridium difficile-associated diarrhoea (CDAD) is a frequently occurring healthcare-associated infection, which is responsible for significant morbidity and mortality amongst elderly patients in healthcare facilities. Environmental contamination is
Sleigh, P.A., Snelling, Anna M., Beggs, Clive B., Smith, Caroline F., Kerr, Kevin G., Banfield, Kathleen R., Roberts, K.   +6 more
core   +5 more sources

Investigation into the mobile genetic elements of Clostridium difficile [PDF]

, 2013
Clostridium difficile is a pathogenic bacterium that can colonise both humans and various animals. Toxin production leads to clinical symptoms ranging from mild to severe diarrhoea and can result in potentially fatal pseudomembranous colitis.
Brouwer, MSM
core  

Chimeric IL‐6/4R‐LL37 Engineered Macrophages Achieve Synchronized Inflammation Control and Antimicrobial Defence in Sepsis

Advanced Science, EarlyView.
Engineered macrophages programmed in situ by LNP‐delivered IL‐6/4 fusion and LL37 mRNAs simultaneously dampen cytokine storm, promote M2‐like repair, and enhance direct bacterial killing in sepsis. This combinatorial strategy restores T cell and macrophage function, lowers organ bacterial burden, and improves survival, highlighting a precision, host ...
Tianyang Jie, Zheyu Zhang, Hao Zhang, Linke Bian, Penglong Zheng, Sijia Zhou, Minqi Wang, Mingyu Qu, Yufei Wang, Xinhua Qu, Bing Yue   +10 more
wiley   +1 more source

A Review of Biobutanol: Eco-Friendly Fuel of the Future—History, Current Advances, and Trends

Fuels
Biobutanol is becoming more relevant as a promising alternative biofuel, primarily due to its advantageous characteristics. These include a higher energy content and density compared to traditional biofuels, as well as its ability to mix effectively with
Victor Alejandro Serrano-Echeverry, Carlos Alberto Guerrero-Fajardo, Karol Tatiana Castro-Tibabisco   +2 more
doaj   +1 more source

In vitro and in vivo characterization of Clostridium scindens bile acid transformations

Gut Microbes, 2019
The human gut hosts trillions of microorganisms that exert a profound influence on human biology. Gut bacteria communicate with their host by secreting small molecules that can signal to distant organs in the body.
Solenne Marion, Nicolas Studer, Lyne Desharnais, Laure Menin, Stéphane Escrig, Anders Meibom, Siegfried Hapfelmeier, Rizlan Bernier-Latmani   +7 more
doaj   +1 more source