Results 71 to 80 of about 253,202 (292)

A case of gas gangrene with fatal outcome (gas gangrene: A case report) [PDF]

open access: yesSerbian Journal of Anesthesia and Intensive Therapy
Introduction: The clinical course of gas gangrene is often rapidly progressive, with a fatal outcome in up to 80% of treated cases. The disease is most commonly a consequence of trauma or surgical interventions.
Pavić Slađana   +3 more
doaj   +1 more source

Clostridium perenne and Clostridium paraperfringens: Later Subjective Synonyms of Clostridium barati [PDF]

open access: yesInternational Journal of Systematic Bacteriology, 1982
Identical electrophoretic patterns of cellular proteins were detected with ATCC 27638, ATCC 25782, and ATCC 27639, the type strains of Clostridium barati (Prevot 1938) Holdeman and Moore 1970, C. perenne (Prevot 1940) McClung and McCoy 1957, and C. paraperfringens Nakamura et al.
E. P. CATO   +2 more
openaire   +1 more source

F‐Type Pyocin Versus Phage λ Tail: Conserved Hub, Divergent Fibers

open access: yesAdvanced Science, EarlyView.
Near‐atomic cryo‐EM structures of a Gram‐negative F‐type pyocin reveal a conserved tail tip architecture shared with bacteriophage λ together with a previously unrecognized side‐fiber attachment mode. These findings provide new insight into tailocin assembly and host recognition and establish a structural framework for engineering precision ...
Zhiwei Gu   +5 more
wiley   +1 more source

Programming Gut Microbiome Function Through Cross‐Feeding: From Ecological Mechanisms to Live Biotherapeutics

open access: yesAdvanced Science, EarlyView.
This graphical abstract presents gut microbial cross‐feeding through a Mechanism–Technology–Application framework. It summarizes major resource‐transfer modes, the experimental and computational tools used to establish causality, and potential interventions involving dietary substrates, live biotherapeutic products, and engineered microbes.
Chuankai Sun   +7 more
wiley   +1 more source

Cysteine Thioaldehydes: Photolytic Generation, Reactivity, and Biological Implications

open access: yesAngewandte Chemie, EarlyView.
Photolysis of cysteine phenacylsulfides bearing non‐conjugating electron‐withdrawing substituents leads to high conversions into cysteine thioaldehydes through a Norrish type‐II pathway. This methodology enabled the study of the aqueous reactivity of these important biosynthetic intermediates, which, depending on peptide sequence, pH and buffer ...
Ardra Karthika   +9 more
wiley   +2 more sources

Recent advances in the positive role of Clostridium in autoimmune diseases: as a crucial regulator of restoring immune-metabolic equilibrium

open access: yesFrontiers in Immunology
Autoimmune diseases (ADs) are a group of conditions characterized by an overactive immune response that damages one or more organs or tissues of the body.
Jing-Yi Zhan   +10 more
doaj   +1 more source

Nanonbiosensors; Rapid detection of Salmonella, Clostridium, Escherichia, and Brucella spp. infections [PDF]

open access: yesArchives of Razi Institute
Zoonotic diseases, which are infectious diseases transmitted from animals to humans, represent a significant global health concern. Despite efforts to eradicate or control these diseases, healthcare systems continue to face a substantial burden due to ...
Soheila Chaleshgari   +3 more
doaj   +1 more source

The ‘in vivo lifestyle’ of bile acid 7α-dehydroxylating bacteria: comparative genomics, metatranscriptomic, and bile acid metabolomics analysis of a defined microbial community in gnotobiotic mice

open access: yesGut Microbes, 2020
The formation of secondary bile acids by gut microbes is a current topic of considerable biomedical interest. However, a detailed understanding of the biology of anaerobic bacteria in the genus Clostridium that are capable of generating secondary bile ...
Jason M. Ridlon   +21 more
doaj   +1 more source

Oral Nanomicelle‐Mediated Sequential Butyrate Production in the Intestine for Ulcerative Colitis and Immunosuppression Treatment

open access: yesAdvanced Science, EarlyView.
After oral administration, inodorous GLU‐BA self‐assembles into nanomicelles in aqueous environments to resist premature gastric adsorption. Upon reaching the intestine, endogenous esterases rapidly cleave the built‐in ester bonds in these nanomicelles to release BA and GLU, with GLU further metabolized by gut microbiota to gradually generate BA ...
Feifei Xin   +9 more
wiley   +1 more source

Prevalence and pathogenicity of binary toxin–positive Clostridium difficile strains that do not produce toxins A and B

open access: yesNew Microbes and New Infections, 2015
Clostridium difficile causes antibiotic-associated diarrhoea and pseudomembranous colitis. The main virulence factors of C. difficile are the toxins A (TcdA) and B (TcdB). A third toxin, called binary toxin (CDT), can be detected in 17% to 23% of strains,
C. Eckert   +15 more
doaj   +1 more source

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