Results 51 to 60 of about 362,624 (297)

Parameter estimation of Stochastic Logistic Model : Levenberg-Marquardt Method [PDF]

open access: yes, 2009
In this paper, we estimate the drift and diffusion parameters of the stochas- tic logisticmodels for the growth of Clostridium Acetobutylicum P262 using Levenberg- Marquardt optimization method of non linear least squares.
Abd. Rahman, Haliza   +5 more
core  

Taxonogenomic description of four new Clostridium species isolated from human gut: ‘Clostridium amazonitimonense’ , ‘Clostridium merdae’ , ‘Clostridium massilidielmoense’ and ‘Clostridium nigeriense’

open access: yesNew Microbes and New Infections, 2018
Culturomics investigates microbial diversity of the human microbiome by combining diversified culture conditions, matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and 16S rRNA gene identification. The present study allowed identification of four putative new Clostridium sensu stricto species: 'Clostridium amazonitimonense ...
Alou, M. T.   +15 more
openaire   +5 more sources

Time‐Controlled Refrigerated Stem Cell Therapy Mitigates Scleroderma Fibrosis via Modulation of Mitochondrial Autophagy and Gut Metabolism

open access: yesAdvanced Science, EarlyView.
This study established an RT‐MSCs‐based therapeutic approach for scleroderma in mice. RT‐MSCs attenuated fibrosis by regulating mitochondrial autophagy and restored gut microbiota homeostasis. Metabolomic analyses confirmed recovery of key metabolites, and RT‐MSCs demonstrated favorable lesion targeting and safety profiles.
Xue Xia   +5 more
wiley   +1 more source

A Novel Surface Plasmon Resonance Biosensor for the Rapid Detection of Botulinum Neurotoxins

open access: yesBiosensors, 2017
Botulinum neurotoxins (BoNTs) are Category A agents on the NIAID (National Institute of Allergy and Infectious Diseases) priority pathogen list owing to their extreme toxicity and the relative ease of production. These deadly toxins, in minute quantities
Kruti Patel   +5 more
doaj   +1 more source

Comparison of the Etest and Sensititre methods for anaerobe susceptibility testing

open access: yesMicrobiologia Medica, 2023
Background and Aims: Antimicrobial susceptibility testing of anaerobic clinical isolates is of paramount importance for patient therapy and resistance monitoring.
Karin Puechler   +5 more
doaj   +1 more source

Dietary-based gut flora modulation against Clostridium difficile onset [PDF]

open access: yes, 2007
Clostridium difficile infection is a frequent complication of antibiotic therapy in hospitalised patients, which today is attracting more attention than ever and has led to its classification as a 'superbug'.
Gibson, G.R.   +2 more
core   +1 more source

Cryo‐EM Structure Guided Engineering of Botulinum Neurotoxin A With Advanced Receptor Binding Affinity and Therapeutical Benefits

open access: yesAdvanced Science, EarlyView.
The butterfly unfolded wing in an open form structure of botulinum neurotoxin type A (BoNT/A) at physiological‐state was confirmed at 2.85 Å resolution by cryo‐electron microscopy (cryo‐EM). Structure‐guided protein engineering significantly enhanced the receptor‐binding affinity, therapeutic efficacy, and safety of the engineered toxin variants ...
Wenrui Wang   +16 more
wiley   +1 more source

Maternal Preconception Antibiotic Exposure Disrupts Microbial Succession: A Transgenerational Risk for Offspring Gut Mucosal Immaturity and Colitis Susceptibility

open access: yesAdvanced Science, EarlyView.
This study reveals that maternal antibiotic exposure prior to conception disrupts intergenerational gut microbial succession. By enhancing maternal‐offspring microbial transmission, altering microbial developmental trajectories and increasing selective pressures during community assembly, these disturbances lead to persistent gut mucosal immaturity and
Yuzhu Chen   +8 more
wiley   +1 more source

Exploitation of food feedstock and waste for production of biobutanol

open access: yesCzech Journal of Food Sciences, 2009
Nine strains of solventogenic clostridia including the species C. acetobutylicum, C. beijerinckii, C. pasteurianum, and C. saccharoperbutylacetonicum were tested for the solvents production using potato, maize, and sugar beet molasses as substrates.
Petra Patáková   +5 more
doaj   +1 more source

CLOSTRIDIUM BOTULINUM [PDF]

open access: yes, 2022
Rod Clostridium čine sporogene, gram-pozitivne, anaerobne štapićaste bakterije. Pripadnici ovog roda imaju industrijski i medicinski značaj, obzirom da proizvode opasne toksine. Vrsta Clostridium botulinum široko je rasprostranjena, a proizvodi najotrovniji poznati toksin, botulinski neurotoksin, koji zbog jedinstvenih farmakoloških obilježja ima ...
openaire   +2 more sources

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