Results 11 to 20 of about 150,054 (232)

Chromosomal integration of the pSOL1 megaplasmid of Clostridium acetobutylicum for continuous and stable advanced biofuels production. [PDF]

Nat Microbiol
Biofuel production by Clostridium acetobutylicum is compromised by strain degeneration due to loss of its pSOL1 megaplasmid. Here we used engineering biology to stably integrate pSOL1 into the chromosome together with a synthetic isopropanol pathway.
Ehsaan M, Yoo M, Kuit W, Foulquier C, Soucaille P, Minton NP.   +5 more
europepmc   +2 more sources

Clostridium acetobutylicum atpG-Knockdown Mutants Increase Extracellular pH in Batch Cultures [PDF]

Frontiers in Bioengineering and Biotechnology, 2021
ATPase, a key enzyme involved in energy metabolism, has not yet been well studied in Clostridium acetobutylicum. Here, we knocked down the atpG gene encoding the ATPase gamma subunit in C. acetobutylicum ATCC 824 using a mobile group II intron system and
Yu-Sin Jang, Hyeon Jeong Seong, Seong Woo Kwon, Yong-Suk Lee, Jung Ae Im, Haeng Lim Lee, Ye Rin Yoon, Sang Yup Lee   +7 more
doaj   +2 more sources

Identification and regulation of an alternative PTS for disaccharide utilization in Clostridium acetobutylicum [PDF]

Applied and Environmental Microbiology
Clostridium acetobutylicum is an important solventogenic bacterium capable of acetone-butanol-ethanol fermentation by utilizing a variety of carbon sources.
Zhenxing Ren, Zili Qiu, Yali Tian, Mengcheng You, Chenggang Xu   +4 more
doaj   +2 more sources

Effects of Carbon Ion Beam Irradiation on Butanol Tolerance and Production of Clostridium acetobutylicum. [PDF]

Front Microbiol, 2020
Clostridium acetobutylicum (C. acetobutylicum) has considerable potential for use in bioenergy development. Owing to the repeated use of traditional mutagenesis methods, the strains have developed a certain tolerance.
Gao Y, Zhang M, Zhou X, Guo X, Lei C, Li W, Lu D.   +6 more
europepmc   +2 more sources

Trends in Systems Biology for the Analysis and Engineering of Clostridium acetobutylicum Metabolism

Trends in Microbiology, 2020
Clostridium acetobutylicum has received renewed interest worldwide as a promising producer of biofuels and bulk chemicals such as n-butanol, 1,3-propanediol, 1,3-butanediol, isopropanol, and butyrate. To develop commercial processes for the production of
Philippe Soucaille, Minyeong Yoo
exaly   +2 more sources

Cross-talk between engineered Clostridium acetobutylicum and Clostridium ljungdahlii in syntrophic cocultures enhances isopropanol and butanol production [PDF]

Frontiers in Microbiology
There is a need for efficient and sustainable production of essential chemicals such as isopropanol and butanol from renewable sugar feedstocks. Microbial fermentations use glycolysis, and as result, a third of the sugar carbon is lost to CO2 through ...
Jonathan K. Otten, Jonathan K. Otten, John D. Hill, John D. Hill, Noah B. Willis, Noah B. Willis, Joseph Dougherty, Andrew Dalton, Eleftherios T. Papoutsakis, Eleftherios T. Papoutsakis, Eleftherios T. Papoutsakis   +10 more
doaj   +2 more sources

A CRISPR/Anti-CRISPR Genome Editing Approach Underlines the Synergy of Butanol Dehydrogenases in Clostridium acetobutylicum DSM 792. [PDF]

Appl Environ Microbiol, 2020
An efficient CRISPR-Cas9 editing tool based on a previous two-plasmid system was developed for Clostridium acetobutylicum and used to investigate the contribution of chromosomal butanol dehydrogenase genes during solventogenesis. Thanks to the control of
Wasels F, Chartier G, Hocq R, Lopes Ferreira N.   +3 more
europepmc   +2 more sources

RRNPP-type quorum sensing affects solvent formation and sporulation in <i>Clostridium acetobutylicum</i>. [PDF]

Microbiology (Reading), 2020
The strictly anaerobic bacterium Clostridium acetobutylicum is well known for its ability to convert sugars into organic acids and solvents, most notably the potential biofuel butanol. However, the regulation of its fermentation metabolism, in particular
Kotte AK, Severn O, Bean Z, Schwarz K, Minton NP, Winzer K.   +5 more
europepmc   +2 more sources

Impact of iron reduction on the metabolism of Clostridium acetobutylicum. [PDF]

Environ Microbiol, 2019
Summary Iron is essential for most living organisms. In addition, its biogeochemical cycling influences important processes in the geosphere (e.g., the mobilization or immobilization of trace elements and contaminants). The reduction of Fe(III) to Fe(II)
List C, Hosseini Z, Lederballe Meibom K, Hatzimanikatis V, Bernier-Latmani R.   +4 more
europepmc   +2 more sources

Gene coexpression network analysis reveals a novel metabolic mechanism of Clostridium acetobutylicum responding to phenolic inhibitors from lignocellulosic hydrolysates. [PDF]

Biotechnol Biofuels, 2020
Background Lignocellulosic biomass is a promising resource of renewable biochemicals and biofuels. However, the presence of inhibitors existing in lignocellulosic hydrolysates (LCH) is a great challenge to acetone-butanol-ethanol (ABE) fermentation by ...
Liu H, Zhang J, Yuan J, Jiang X, Jiang L, Li Z, Yin Z, Du Y, Zhao G, Liu B, Huang D.   +10 more
europepmc   +2 more sources