The role of ethanol oxidation during carboxydotrophic growth of Clostridium autoethanogenum [PDF]
Microbial Biotechnology, 2023 The Wood–Ljungdahl pathway is an ancient metabolic route used by acetogenic carboxydotrophs to convert CO into acetate, and some cases ethanol. When produced, ethanol is generally seen as an end product of acetogenic metabolism, but here we show that it ...
Martijn Diender +5 more
doaj +4 more sources
Metabolic Engineering Interventions for Sustainable 2,3-Butanediol Production in Gas-Fermenting Clostridium autoethanogenum [PDF]
mSystems, 2022 Gas fermentation provides a promising platform to turn low-cost and readily available single-carbon waste gases into commodity chemicals, such as 2,3-butanediol.
Parsa Ghadermazi +3 more
doaj +5 more sources
Metabolic engineering of Clostridium autoethanogenum for selective alcohol production [PDF]
Metabolic Engineering, 2017 Gas fermentation using acetogenic bacteria such as Clostridium autoethanogenum offers an attractive route for production of fuel ethanol from industrial waste gases.
Fungmin Liew +2 more
exaly +4 more sources
Clostridium autoethanogenum isopropanol production via native plasmid pCA replicon [PDF]
Frontiers in Bioengineering and Biotechnology, 2022 Clostridium autoethanogenum is a model gas-fermenting acetogen for commercial ethanol production. It is also a platform organism being developed for the carbon-negative production of acetone and isopropanol by gas fermentation. We have assembled a 5.5 kb
Robert Nogle +15 more
doaj +2 more sources
Absolute Proteome Quantification in the Gas-Fermenting Acetogen Clostridium autoethanogenum [PDF]
mSystems, 2022 Microbes that can recycle one-carbon (C1) greenhouse gases into fuels and chemicals are vital for the biosustainability of future industries. Acetogens are the most efficient known microbes for fixing carbon oxides CO2 and CO.
Kaspar Valgepea +11 more
doaj +2 more sources
Autotrophic and Mixotrophic Batch Processes with Clostridium autoethanogenum LAbrini in Stirred Tank Bioreactors with Continuous Gassing [PDF]
MicroorganismsSimultaneous conversion of syngas and sugars is a promising approach to overcome limitations of syngas fermentation. Clostridium autoethanogenum LAbrini, obtained by adaptive laboratory evolution, is known to show improved autotrophic process performance.
Anne Oppelt +3 more
doaj +2 more sources
Metabolic engineering of Clostridium autoethanogenum for ethyl acetate production from CO [PDF]
Microbial Cell Factories, 2022 Background Ethyl acetate is a bulk chemical traditionally produced via energy intensive chemical esterification. Microbial production of this compound offers promise as a more sustainable alternative process.
James C. Dykstra +7 more
doaj +2 more sources
Endogenous CRISPR/Cas systems for genome engineering in the acetogens Acetobacterium woodii and Clostridium autoethanogenum [PDF]
Frontiers in Bioengineering and Biotechnology, 2023 Acetogenic bacteria can play a major role in achieving Net Zero through their ability to convert CO2 into industrially relevant chemicals and fuels. Full exploitation of this potential will be reliant on effective metabolic engineering tools, such as ...
Margaux Poulalier-Delavelle +4 more
doaj +2 more sources
Agr Quorum Sensing influences the Wood-Ljungdahl pathway in Clostridium autoethanogenum [PDF]
Scientific Reports, 2022 Acetogenic bacteria are capable of fermenting CO2 and carbon monoxide containing waste-gases into a range of platform chemicals and fuels. Despite major advances in genetic engineering and improving these biocatalysts, several important physiological ...
Pawel Piatek +7 more
doaj +2 more sources
Modeling a co-culture of Clostridium autoethanogenum and Clostridium kluyveri to increase syngas conversion to medium-chain fatty-acids [PDF]
Computational and Structural Biotechnology Journal, 2020 Microbial fermentation of synthesis gas (syngas) is becoming more attractive for sustainable production of commodity chemicals. To date, syngas fermentation focuses mainly on the use of Clostridium species for the production of small organic molecules ...
Sara Benito-Vaquerizo +6 more
doaj +2 more sources