Results 41 to 50 of about 142,227 (207)

How Can We Personalize the Delivery of Onabotulinumtoxin‐A for Patients With Neurogenic Lower Urinary Tract Dysfunction?

open access: yesNeurourology and Urodynamics, EarlyView.
ABSTRACT Background & Aims Neurogenic lower urinary tract dysfunction (NLUTD) can produce bothersome urinary symptoms, impact quality of life, and in some cases, lead to deterioration of upper urinary tract function. Intradetrusor injection of onabotulinumtoxin‐A (BoNT‐A) is approved for NLUTD in patients who have an inadequate response to or ...
Shirley L. Wang   +2 more
wiley   +1 more source

Therapeutic Uses and Efficacy of Botulinum Toxin in Orofacial Medicine: A Dental Perspective

open access: yesToxins
Botulinum neurotoxin (BoNT) is the exotoxin of Clostridium botulinum, a Gram-positive, spore-forming bacterium [...]
Kazuya Yoshida, Merete Bakke
doaj   +1 more source

Conjugative botulinum neurotoxin-encoding plasmids in Clostridium botulinum. [PDF]

open access: yesPLoS ONE, 2010
Clostridium botulinum produces seven distinct serotypes of botulinum neurotoxins (BoNTs). The genes encoding different subtype neurotoxins of serotypes A, B, F and several dual neurotoxin-producing strains have been shown to reside on plasmids ...
Kristin M Marshall   +2 more
doaj   +1 more source

Characterization of the spore surface and exosporium proteins of Clostridium sporogenes; implications for Clostridium botulinum group I strains

open access: yesFood microbiology, 2016
Clostridium sporogenes is a non-pathogenic close relative and surrogate for Group I (proteolytic) neurotoxin-producing Clostridium botulinum strains.
T. K. Janganan   +7 more
semanticscholar   +1 more source

Construction of an O2‐responsive engineering bioreactor for enhanced indole‐3‐propionic acid production and deoxynivalenol detoxification

open access: yesResponsive Materials, EarlyView.
An oxygen‐responsive living bioreactor was engineered via interspecies protoplast fusion, converting oxygen from an inhibitory stress into a programmable signal for sustained indole‐3‐propionic acid (IPA) production. This genetically encoded bioreactor enables robust aerobic operation and therapeutic efficacy of deoxynivalenol detoxification in vivo ...
Ning Ma   +8 more
wiley   +1 more source

PHÂN LẬP VÀ XÁC ĐỊNH TÍNH NHẠY CẢM KHÁNG SINH CỦA VI KHUẨN (CLOSTRIDIUM BOTULINUM) TỪ VỊT VÀ MÔI TRƯỜNG CHĂN THẢ TẠI THÀNH PHỐ CẦN THƠ

open access: yesTạp chí Khoa học Đại học Cần Thơ, 2012
Nghiên cứu phân lập và xác định tính nhạy cảm đối với kháng sinh của vi khuẩn Clostridium botulinum trên vịt và môi trường chăn thả ở huyện Vĩnh Thạnh, Thới Lai và Cờ Đỏ được thực hiện tư? tha?ng 01/2009 đê?n tha?ng 12/2011.
Nguyễn Đức Hiền
doaj  

Polyesterase activity and thermostability of carboxylesterases from Thermoleophilum album YS‐3

open access: yesThe FEBS Journal, EarlyView.
Three novel α/β‐hydrolases from thermophilic bacterium Thermoleophilum album display carboxylesterase and polyesterase activity. These enzymes hydrolyse PET, PLA and PCL both at high and moderate temperatures. TA21 shows superior activity, efficiently converting MHET to terephthalic acid. Structural features underlying substrate binding highlight their
Tatyana N. Chernikova   +6 more
wiley   +1 more source

Impact of Clostridium botulinum genomic diversity on food safety

open access: yesCurrent Opinion in Food Science, 2016
Highlights • C. botulinum Groups I and II form botulinum neurotoxin and cause foodborne botulism.• Increased knowledge of C. botulinum Group I and II genomes and neurotoxin diversity.• Impact on food safety via improved surveillance and tracing/tracking ...
M. Peck, A. H. V. van Vliet
semanticscholar   +1 more source

Repurpose an FDA‐Approved Antibody Using DARPin‐Scaffolded Bridge Protein

open access: yesChemistry–Methods, Volume 6, Issue 5, May 2026.
The cell line and scalable upstream/downstream process development needed for every new monoclonal antibody are both highly expensive and time‐consuming, significantly increasing the cost of new antibody therapeutics. By contrast, the production of many synthetic binders can be accomplished rapidly and with lower production costs.
Michael Woolley   +4 more
wiley   +1 more source

Introduction to Toxins Special Issue on Botulinum Toxins: New Uses in the Treatment of Diseases (2nd Edition)

open access: yesToxins
Clostridium botulinum strains produce seven antigenically distinct botulinum neurotoxins (BoNTs), referred to as serotypes A–G, and a hybrid toxin called F/A [...]
Siro Luvisetto
doaj   +1 more source

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