Results 1 to 10 of about 2,470 (88)

Molecular epidemiology and antimicrobial resistance of Clostridioides difficile in Germany, 2014–2019

International Journal of Medical Microbiology, 2021
Clostridioides difficile is a Gram positive spore-forming rod and mainly responsible for nosocomial diarrhea in developed nations. Molecular and antimicrobial surveillance is important for monitoring the strain composition including genotypes of high ...
Ahmed Mohamed Mostafa Abdrabou, Zia Ul Habib Bajwa, Alexander Halfmann, Alexander Mellmann, Anna Nimmesgern, Lena Margardt, Markus Bischoff, Lutz von Müller, Barbara Gärtner, Fabian K. Berger   +9 more
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Assessment of the Effect of Multidrug Resistance Clostridium difficile Clinical Strains on the Dynamics of Clostridium difficile Infection Rate at Pediatric Oncological Hospital

Эпидемиология и вакцинопрофилактика, 2021
Relevance. At the children's oncological hospital guidelines to treat patients with several groups of antibiotics at the same time, which ensures the formation of multi-resistant strains of Clostridium difficile, which have a selective advantage for the ...
M. G. Shvydkaya, A. M. Zatevalov, D. T. Dzhandarova, S. D. Mitrokhin, O. E. Orlova   +4 more
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Clostridium difficile Infection [PDF]

Medical Clinics of North America, 2013
Clostridium difficile is emerging as a common cause of infectious diarrhea. Incidence has increased dramatically since 2000, associated with a new strain that features both increased toxin production and increased resistance to antibiotics. For patients with mild to moderate disease, oral metronidazole is usually the first choice of treatment, and ...
Christopher L, Knight, Christina M, Surawicz   +1 more
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Clostridium difficile infection [PDF]

Nature Reviews Disease Primers, 2016
Infection of the colon with the Gram-positive bacterium Clostridium difficile is potentially life threatening, especially in elderly people and in patients who have dysbiosis of the gut microbiota following antimicrobial drug exposure. C. difficile is the leading cause of health-care-associated infective diarrhoea. The life cycle of C.
Smits, W.K., Lyras, D., Lacy, D.B., Wilcox, M.H., Kuijper, E.J.   +4 more
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Molecular epidemiology and antimicrobial resistance of Clostridioides difficile detected in chicken, soil and human samples from Zimbabwe

International Journal of Infectious Diseases, 2020
Background: Clostridioides difficile is the major cause of infectious nosocomial diarrhoea in industrialized nations. Data on the occurrence of C. difficile in Africa, ribotype (RT) distribution, antimicrobial susceptibility patterns and potential ...
Fabian K. Berger, Alexander Mellmann, Markus Bischoff, Lutz von Müller, Sören L. Becker, Clifford Simango, Barbara Gärtner   +6 more
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Риск развития Clostridium difficile инфекции, связанный с применением различных групп антибиотиков и их сочетаний, у детей в онкологическом стационаре

Microbiology Independent Research Journal, 2020
Пациенты детского онкологического стационара находятся в группе риска развития Clostridium difficile инфекции. Цель данного исследования состояла в определении степени риска развития Clostridium difficile инфекции в детском онкологическом стационаре ...
М. Г. Швыдкая, А. М. Затевалов, Д. Т. Джандарова, С. Д. Митрохин   +3 more
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Clostridium difficile инфекции у пациентов детского онкологического стационара: проблемы культивирования анаэробной кишечной флоры и лечения

Microbiology Independent Research Journal, 2021
В последние годы в мире наблюдается рост числа инфекционных заболеваний, вызванных Clostridium difficile со значи-тельным увеличением рецидивов и смертности, в том числе среди онкологических больных – пациентов стационаров.
М. Г. Швыдкая, Д. Т. Джандарова, С. Д. Митрохин   +2 more
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Prevalence and pathogenicity of binary toxin–positive Clostridium difficile strains that do not produce toxins A and B

New Microbes and New Infections, 2015
Clostridium difficile causes antibiotic-associated diarrhoea and pseudomembranous colitis. The main virulence factors of C. difficile are the toxins A (TcdA) and B (TcdB). A third toxin, called binary toxin (CDT), can be detected in 17% to 23% of strains,
C. Eckert, A. Emirian, A. Le Monnier, L. Cathala, H. De Montclos, J. Goret, P. Berger, A. Petit, A. De Chevigny, H. Jean-Pierre, B. Nebbad, S. Camiade, R. Meckenstock, V. Lalande, H. Marchandin, F. Barbut   +15 more
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Epidemiology of Clostridioides difficile Infections in Germany, 2010–2019: A Review from Four Public Databases

Infectious Diseases and Therapy, 2023
Introduction Clostridioides difficile infection (CDI) is a recognized global threat especially for vulnerable populations. It is of particular concern to healthcare providers as it is found in both hospital and community settings, with severe courses ...
Gordon Brestrich, Frederick J. Angulo, Fabian K. Berger, Christian Brösamle, Stefan Hagel, Andreas Leischker, Christoph Lübbert, Friederike Maechler, Sophie-Susann Merbecks, Nadia Minarovic, Jennifer C. Moïsi, Lutz von Müller, Phillip A. Reuken, Thomas Weinke, Holly Yu, Alexander Mellmann   +15 more
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Infections caused by Clostridium difficile in cancer patients

Сибирский онкологический журнал, 2019
The purpose of the study was to determine the role of antibiotics as a risk factor of Clostridium difficile-associated diarrhea in hospitalized cancer patients.Material and Methods. The study included 844 hospitalized cancer patients with diarrhea.
I. A. Klyuchnikova, I. N. Petukhova, Z. V. Grigorievskaya, N. S. Bagirova, I. V. Tereshchenko, N. V. Dmitrieva   +5 more
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