Results 1 to 10 of about 55,612 (128)

Asymptomatic and yet C. difficile-toxin positive? Prevalence and risk factors of carriers of toxigenic Clostridium difficile among geriatric in-patients [PDF]

BMC Geriatrics, 2016
Background Clostridium difficile infections (CDI) are the most frequent cause of diarrhoea in hospitals. Geriatric patients are more often affected by the condition, by a relapse and complications.
Klaus Nissle, Daniel Kopf, Alexander Rösler   +2 more
doaj   +4 more sources

Molecular epidemiology and antimicrobial resistance of Clostridioides difficile in Germany, 2014–2019

International Journal of Medical Microbiology, 2021
Clostridioides difficile is a Gram positive spore-forming rod and mainly responsible for nosocomial diarrhea in developed nations. Molecular and antimicrobial surveillance is important for monitoring the strain composition including genotypes of high ...
Ahmed Mohamed Mostafa Abdrabou, Zia Ul Habib Bajwa, Alexander Halfmann, Alexander Mellmann, Anna Nimmesgern, Lena Margardt, Markus Bischoff, Lutz von Müller, Barbara Gärtner, Fabian K. Berger   +9 more
doaj   +1 more source

Assessment of the Effect of Multidrug Resistance Clostridium difficile Clinical Strains on the Dynamics of Clostridium difficile Infection Rate at Pediatric Oncological Hospital

Эпидемиология и вакцинопрофилактика, 2021
Relevance. At the children's oncological hospital guidelines to treat patients with several groups of antibiotics at the same time, which ensures the formation of multi-resistant strains of Clostridium difficile, which have a selective advantage for the ...
M. G. Shvydkaya, A. M. Zatevalov, D. T. Dzhandarova, S. D. Mitrokhin, O. E. Orlova   +4 more
doaj   +1 more source

Clostridium difficile Infection [PDF]

Medical Clinics of North America, 2013
Clostridium difficile is emerging as a common cause of infectious diarrhea. Incidence has increased dramatically since 2000, associated with a new strain that features both increased toxin production and increased resistance to antibiotics. For patients with mild to moderate disease, oral metronidazole is usually the first choice of treatment, and ...
Christopher L, Knight, Christina M, Surawicz   +1 more
  +7 more sources

Clostridium difficile infection [PDF]

Nature Reviews Disease Primers, 2016
Infection of the colon with the Gram-positive bacterium Clostridium difficile is potentially life threatening, especially in elderly people and in patients who have dysbiosis of the gut microbiota following antimicrobial drug exposure. C. difficile is the leading cause of health-care-associated infective diarrhoea. The life cycle of C.
Smits, W.K., Lyras, D., Lacy, D.B., Wilcox, M.H., Kuijper, E.J.   +4 more
openaire   +8 more sources

Molecular epidemiology and antimicrobial resistance of Clostridioides difficile detected in chicken, soil and human samples from Zimbabwe

International Journal of Infectious Diseases, 2020
Background: Clostridioides difficile is the major cause of infectious nosocomial diarrhoea in industrialized nations. Data on the occurrence of C. difficile in Africa, ribotype (RT) distribution, antimicrobial susceptibility patterns and potential ...
Fabian K. Berger, Alexander Mellmann, Markus Bischoff, Lutz von Müller, Sören L. Becker, Clifford Simango, Barbara Gärtner   +6 more
doaj   +1 more source

Susceptibility of hamsters to clostridium difficile isolates of differing toxinotype [PDF]

, 2013
Clostridium difficile is the most commonly associated cause of antibiotic associated disease (AAD), which caused ~21,000 cases of AAD in 2011 in the U.K. alone.
A Buckley, Anthony M. Buckley, B Elliott, C Rousseau, C Schwan, D Drudy, D Goulding, D Lyras, Denise Candlish, DM Guerrero, F Miyajima, Gillian R. Douce, H Huang, H Kim, H Kim, I Duerden, I Vesteinsdottir, J Andrews, J Kim, J Ng, J Pépin, J Wang, Janice Spencer, JG Bartlett, JM Lanis, June J. Irvine, JW Marsh, LA Petrella, Lindsay M. Maclellan, LJ Deakin, M Arvand, M He, M Merrigan, M Rupnik, MH Wilcox, MH Wilcox, Michel R. Popoff, MM Nerandzic, MSM Brouwer, N Razaq, N Stoesser, P Vohra, R Stabler, R Stabler, S Kamiya, S Kuehne, SA Villano, SP Sambol, SP Sambol, ST Cartman, TS Steiner, V Braun, V Casas, Y Ogura   +53 more
core   +14 more sources

Риск развития Clostridium difficile инфекции, связанный с применением различных групп антибиотиков и их сочетаний, у детей в онкологическом стационаре

Microbiology Independent Research Journal, 2020
Пациенты детского онкологического стационара находятся в группе риска развития Clostridium difficile инфекции. Цель данного исследования состояла в определении степени риска развития Clostridium difficile инфекции в детском онкологическом стационаре ...
М. Г. Швыдкая, А. М. Затевалов, Д. Т. Джандарова, С. Д. Митрохин   +3 more
doaj   +1 more source

Clostridium difficile инфекции у пациентов детского онкологического стационара: проблемы культивирования анаэробной кишечной флоры и лечения

Microbiology Independent Research Journal, 2021
В последние годы в мире наблюдается рост числа инфекционных заболеваний, вызванных Clostridium difficile со значи-тельным увеличением рецидивов и смертности, в том числе среди онкологических больных – пациентов стационаров.
М. Г. Швыдкая, Д. Т. Джандарова, С. Д. Митрохин   +2 more
doaj   +1 more source

Incidence and Outcomes Associated With Clostridium difficile Infections: A Systematic Review and Meta-analysis [PDF]

, 2020
Importance: An understanding of the incidence and outcomes of Clostridium difficile infection (CDI) in the United States can inform investments in prevention and treatment interventions.
Balkenende, Erin, Blevins, Amy E., Chiang, Hsiu-Yin, Chorazy, Margaret L., Diekema, Daniel J., Herwaldt, Loreen A., Khader, Karim, Kuxhausen, Michelle F., Marra, Alexandre R., McDanel, Jennifer S., Nair, Rajeshwari, Nelson, Richard E., Perencevich, Eli N., Samore, Matthew, Schweizer, Marin L., Ward, Melissa A.   +15 more
core   +1 more source