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Gastroenterology Clinics of North America, 2001 Clostridium difficile is a major cause of antibiotic-associated diarrhea and colitis. The incidence of infection with this organism is increasing in hospitals worldwide, consequent to the widespread use of broad-spectrum antibiotics. Pathogenic strains of C. difficile produce two protein exotoxins, toxin A and toxin B, that cause colonic mucosal injury
L, Kyne, R J, Farrell, C P, Kelly
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Clinics in Laboratory Medicine, 2010 Clostridium difficile infections (CDIs) have emerged as one of the principal threats to the health of hospitalized and immunocompromised patients. The importance of C difficile colonization is increasingly recognized not only as a source for false-positive clinical testing but also as a source of new infections within hospitals and other health care ...
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Susceptibility of hamsters to clostridium difficile isolates of differing toxinotype [PDF]
, 2013 Clostridium difficile is the most commonly associated cause of antibiotic associated disease (AAD), which caused ~21,000 cases of AAD in 2011 in the U.K. alone.
A Buckley +53 more
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Incidence and Outcomes Associated With Clostridium difficile Infections: A Systematic Review and Meta-analysis [PDF]
, 2020 Importance: An understanding of the incidence and outcomes of Clostridium difficile infection (CDI) in the United States can inform investments in prevention and treatment interventions.
Balkenende, Erin +15 more
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Clostridium difficile infection [PDF]
Nature Reviews Disease Primers, 2016 Infection of the colon with the Gram-positive bacterium Clostridium difficile is potentially life threatening, especially in elderly people and in patients who have dysbiosis of the gut microbiota following antimicrobial drug exposure. C. difficile is the leading cause of health-care-associated infective diarrhoea. The life cycle of C.
Smits, W.K. +4 more
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Clostridium difficile infection [PDF]
The Lancet, 2008 Clostridium difficile is a Gram-positive, anaerobic, spore-producing anaerobe [1] responsible for approximately 50–70% of gastrointestinal infections in hospitalized patients [2, 3]. An episode of C. difficile infection (CDI) is defined as a clinical picture compatible with CDI (i.
Christina M. Surawicz, Ernst J. Kuipers
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Clostridium-difficile-Kolitis [PDF]
Der Gastroenterologe, 2014 Die (rezidivierende) Clostridium-difficile-Infektion (CDI) stellt bereits jetzt ein substanzielles Problem dar, sind mit ihr doch nicht nur eine beachtenswerte Morbiditat und Mortalitat assoziiert, sondern auch gesundheitsokonomische und logistische Herausforderungen.
Biedermann, L, Rogler, G
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The burden of clostridium difficile infection in patients with liver cirrhosis [PDF]
, 2019 Clostridium Difficile Infection (CDI) has registered a dramatically increasing incidence in the general population over the past decades. Nowadays, Clostridium Difficile is the leading cause of hospital-acquired diarrhea in Europe and North America ...
Dumitru, Andrada +5 more
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Phage ϕC2 mediates transduction of Tn6215, encoding erythromycin resistance, between Clostridium difficile strains [PDF]
, 2013 UNLABELLED: In this work, we show that Clostridium difficile phage ϕC2 transduces erm(B), which confers erythromycin resistance, from a donor to a recipient strain at a frequency of 10(-6) per PFU.
Chang, Barbara J +5 more
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A Clostridium difficile onkológiai vonatkozásai [PDF]
, 2016 Absztrakt A Clostridium difficile az egyik leggyakoribb fertőzés a daganatos betegek között. Diagnózisát nehezíti, hogy a fertőzés tünetei és az onkológiai kezelések mellékhatásai hasonlóak ...
Telekes, András
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